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BMC Medicine
Published in: BMC Medicine 1/2013

Open Access 01-12-2013 | Question and Answer

Video Q&A: Rapid urine LAM test for HIV-associated TB - potential to reduce deaths? An interview with Stephen Lawn

Author: Stephen D Lawn

Published in: BMC Medicine | Issue 1/2013

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Abstract

In this video Q&A, we talk to Dr Stephen Lawn about the point-of-care LAM test for HIV-associated TB, which has the potential to save lives by improving rapid diagnosis and treatment.
Appendix
Available only for authorised users
Literature
1.
Lawn SD: Point-of-care detection of lipoarabinomannan (LAM) in urine for diagnosis of HIV-associated tuberculosis: a state of the art review. BMC Infect Dis. 2012, 12: 103.CrossRefPubMedPubMedCentral
2.
Lawn SD, Kerkhoff AD, Vogt M, Wood R: Diagnostic accuracy of a low-cost, urine antigen, point-of-care screening assay for HIV-associated pulmonary tuberculosis before antiretroviral therapy: a descriptive study. Lancet Infect Dis. 2012, 12: 201-209.CrossRefPubMedPubMedCentral
3.
Peter JG, Theron G, Zyl-Smit R, Haripersad A, Mottay L, Kraus S, Binder A, Meldau R, Hardy A, Dheda K: Diagnostic accuracy of a urine lipoarabinomannan strip-test for TB detection in HIV-infected hospitalised patients. Eur Respir J. 2012, 40: 1211-1220.CrossRefPubMed
4.
Lawn SD, Kerkhoff AD, Vogt M, Wood R: Clinical significance of lipoarabinomannan detection in urine using a low-cost point-of-care diagnostic assay for HIV-associated tuberculosis. AIDS. 2012, 26: 1635-1643.CrossRefPubMed
5.
Shah M, Variava E, Holmes CB, Coppin A, Golub JE, McCallum J, Wong M, Luke B, Martin DJ, Chaisson RE, Dorman SE, Martinson NA: Diagnostic accuracy of a urine lipoarabinomannan test for tuberculosis in hospitalized patients in a High HIV prevalence setting. J Acquir Immune Defic Syndr. 2009, 52: 145-151.CrossRefPubMedPubMedCentral
6.
Lawn SD, Edwards DJ, Kranzer K, Vogt M, Bekker LG, Wood R: Urine lipoarabinomannan assay for tuberculosis screening before antiretroviral therapy diagnostic yield and association with immune reconstitution disease. AIDS. 2009, 23: 1875-1880.CrossRefPubMed
7.
Minion J, Leung E, Talbot E, Dheda K, Pai M, Menzies D: Diagnosing tuberculosis with urine lipoarabinomannan: systematic review and meta-analysis. Eur Respir J. 2011, 38: 1398-1405.CrossRefPubMed
8.
Wood R, Racow K, Bekker LG, Middelkoop K, Vogt M, Kreiswirth BN, Lawn SD: Lipoarabinomannan in urine during tuberculosis treatment: association with host and pathogen factors and mycobacteriuria. BMC Infect Dis. 2012, 12: 47.CrossRefPubMedPubMedCentral
9.
Lawn SD, Mwaba P, Bates M, Piatek A, Alexander H, Marais BJ, Cuevas LE, McHugh TD, Zijenah L, Kapata N, Abubakar I, McNerney R, Hoelscher M, Memish ZA, Migliori GB, Kim P, Maeurer M, Schito M, Zumla A: Advances in tuberculosis diagnostics: the Xpert MTB/RIF assay and future prospects for a point-of-care test. Lancet Infect Dis. 2013, 13: 349-361.CrossRefPubMedPubMedCentral
10.
Metadata
Title
Video Q&A: Rapid urine LAM test for HIV-associated TB - potential to reduce deaths? An interview with Stephen Lawn
Author
Stephen D Lawn
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Medicine / Issue 1/2013
Electronic ISSN: 1741-7015
DOI
https://doi.org/10.1186/1741-7015-11-158

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