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Open Access 01-12-2013 | Minireview

Genetic heterogeneity in breast cancer: the road to personalized medicine?

Authors: Richard D Baird, Carlos Caldas

Published in: BMC Medicine | Issue 1/2013

Abstract

More women die from breast cancer across the world today than from any other type of malignancy. The clinical course of breast cancer varies tremendously between patients. While some of this variability is explained by traditional clinico-pathological factors (including patient age, tumor stage, histological grade and estrogen receptor status), molecular profiling studies have defined breast cancer subtypes with distinct clinical outcomes. This mini-review considers recent studies which have used genomics technologies in an attempt to identify new biomarkers of prognosis and treatment response. These studies highlight the genetic heterogeneity that exists within breast cancers in space and time.

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The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1741-7015/11/151/prepub

Title: Genetic heterogeneity in breast cancer: the road to personalized medicine?
Authors: Richard D Baird
Carlos Caldas
Publication date: 01-12-2013
Publisher: BioMed Central
Published in: BMC Medicine / Issue 1/2013
Electronic ISSN: 1741-7015
DOI: https://doi.org/10.1186/1741-7015-11-151

ACC 2024 Congress

Springer Medicine

Genetic heterogeneity in breast cancer: the road to personalized medicine?

Abstract

ACC 2024 Congress

Springer Medicine

Abstract

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