Published in:
Open Access
01-11-2010 | Poster presentation
Cord blood hemopoietic progenitor cell toll like receptor expression and function: a mechanism underlying allergic inflammation in early life?
Authors:
Pia Reece, Lynn Crawford, Adrian J Baajtes, Michael M Cyr, Roma Sehmi, Judah A Denburg
Published in:
Allergy, Asthma & Clinical Immunology
|
Special Issue 3/2010
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Excerpt
Neonatal immune responses to environmental stimuli, mediated via TLR, may determine the development of atopy in childhood. Since hemopoietic mechanisms are involved in development and maintenance of allergic inflammation, we investigated alterations in progenitor expression and differentiation profiles after stimulation with TLR agonists. …