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Published in: Allergy, Asthma & Clinical Immunology 2/2014

Open Access 01-12-2014 | Meeting abstract

B cell Semaphorin 4c expression mitigates the airway hyperresponsiveness and acute inflammation which characterize allergic airway disease

Authors: Alex Lei, Di Xue, Marylin Desjardins, Marianne Beland, Bruce Mazer

Published in: Allergy, Asthma & Clinical Immunology | Special Issue 2/2014

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Excerpt

Semaphorin signaling proteins, initially examined in the context of neuronal axon development, have recently been implicated as regulators of immune cell migration. Our laboratory has determined that expression of Semaphorin 4C (Sema4C) is strongly induced on B cells exposed to Th2 stimulation, and we seek to elucidate its mechanism of controlling allergic airway disease. …
Metadata
Title
B cell Semaphorin 4c expression mitigates the airway hyperresponsiveness and acute inflammation which characterize allergic airway disease
Authors
Alex Lei
Di Xue
Marylin Desjardins
Marianne Beland
Bruce Mazer
Publication date
01-12-2014
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1710-1492-10-S2-A26

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