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International Journal of Pediatric Endocrinology
Published in: International Journal of Pediatric Endocrinology 1/2015

Open Access 01-12-2015 | Poster presentation

Sirolimus treatment of severe congenital hyperinsulinism

Authors: Lisa A Amato, Charmian A Quigley, Kris A Neville, Shihab Hameed, Charles F Verge, Helen J Woodhead, Jan L Walker

Published in: International Journal of Pediatric Endocrinology | Special Issue 1/2015

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Excerpt

Sirolimus treatment reduced dependence on octreotide and frequent feeding in 4 infants with CHI in a recent study [1]. We report our experience in a 1 year-old boy with presumed diffuse disease due to a de novo heterozygous ABCC8 missense mutation (p.D1506E). …
Literature
1.
Senniappan S, et al: Sirolimus therapy in infants with severe hyperinsulinemic hypoglycaemia. NEJM. 2014, 370: 1131-7. 10.1056/NEJMoa1310967.CrossRefPubMed
Metadata
Title
Sirolimus treatment of severe congenital hyperinsulinism
Authors
Lisa A Amato
Charmian A Quigley
Kris A Neville
Shihab Hameed
Charles F Verge
Helen J Woodhead
Jan L Walker
Publication date
01-12-2015
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1687-9856-2015-S1-P123

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