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Open Access 01-11-2013 | Meeting abstract

PW01-014 – MEFV methylation analysis in FMF and JRA diseases

Authors: E Tahir Turanli, AK Kirectepe, Ö Kasapçopur

Published in: Pediatric Rheumatology | Special Issue 1/2013

Excerpt

MEFV is the first identified autoinflammatory gene related to Familial Mediterranean Fever (FMF) disease. We previously the tested the hypothesize of epigenetic involvement in FMF, mainly based on the occurrence of FMF in patients without mutations and decreased MEFV transcripts in leukocyte samples independent from mutations. Our study showed that higher methylation level of MEFV second exon CpG island in FMF patients compared to healthy controls (p=0.049) and negative correlation between methylation and expression levels in leucocytes (cor=-0.29, p=0.041 in both groups, cor=-0.36, p=0.035 in FMF samples). …

Title: PW01-014 – MEFV methylation analysis in FMF and JRA diseases
Authors: E Tahir Turanli
AK Kirectepe
Ö Kasapçopur
Publication date: 01-11-2013
Publisher: BioMed Central
Published in: Pediatric Rheumatology / Issue Special Issue 1/2013
Electronic ISSN: 1546-0096
DOI: https://doi.org/10.1186/1546-0096-11-S1-A67

At a glance: The STEP trials

Springer Medicine

PW01-014 – MEFV methylation analysis in FMF and JRA diseases

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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PW01-012 – Canakinumab in patients with FMF

P01-039 – Autonomic functions in children with FMF

PW01-037 – Amyloidosis probability depending on MEFV type

PW01-017 – Urine MMP-3 level as a biomarker for in FMF attack

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