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Pediatric Rheumatology
Published in: Pediatric Rheumatology 1/2013

Open Access 01-11-2013 | Meeting abstract

PW03-014B - Gene-expression profiling study in FMF families

Authors: B Aygun, M Carrabba, M Fabbri, L Gribaldo, M Zarantonello, G Fabio

Published in: Pediatric Rheumatology | Special Issue 1/2013

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Excerpt

The inflammasome complex and the inflammatory pathway have been implicated in the pathogenesis of familial Mediterranean fever (FMF), and recently ASC (apoptosis-associated speck-like protein containing a CARD) mRNA expression was found to be up-regulated in patients carrying MEFV mutations independent of the mutation type. Gene-expression profiling has the capacity to reveal transcriptome profiles to discriminate disease "phenotypes" to understand a given disease and bring to light new diagnostic and predictive biomarkers. …
Metadata
Title
PW03-014B - Gene-expression profiling study in FMF families
Authors
B Aygun
M Carrabba
M Fabbri
L Gribaldo
M Zarantonello
G Fabio
Publication date
01-11-2013
Publisher
BioMed Central
Published in
Pediatric Rheumatology / Issue Special Issue 1/2013
Electronic ISSN: 1546-0096
DOI
https://doi.org/10.1186/1546-0096-11-S1-A241

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PW01-028 – Developing a new severity score for FMF

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PW01-020 – MEFV mutations carrier rate in Central Europe

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