Published in:
Open Access
01-11-2013 | Meeting abstract
P03-013 - Symptomatic neuromuscular sarcoidosis
Authors:
M Mulazzani, C Haberler, F Zimprich, EV Hartl, H Cetin
Published in:
Pediatric Rheumatology
|
Special Issue 1/2013
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Excerpt
Sarcoidosis is a granulomatous disease possibly affecting all organ systems. Less than 10% of sarcoidosis patients develop symptomatic neurological involvement. Although muscular non-caseating granulomas (NCGs) can be found in up to 75% of sarcoidosis patients, muscular symptoms develop only in less than 0.5% of sarcoidosis patients. Corticosteroids (CS) are the mainstay of medical therapy, but their effect on chronic myopathy is not consistent. Additive immunosuppressive therapy with azathioprine, cyclophosphamide, methotrexate, or chloroquine may be necessary in patients inadequately responding to CSs. …