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Open Access 01-11-2013 | Meeting abstract

OR11-005 - Mast cells respond to pathogen signals with IL-1ß

Authors: L Kraas, O Schmetzer, K Krause, E Latz, M Maurer

Published in: Pediatric Rheumatology | Special Issue 1/2013

Excerpt

Mast cells, key effector cells of allergic and innate immune responses, have recently been reported to be an important source of IL-1ß in patients with autoinflammatory conditions such as cryopyrin-associated-periodic-fever syndromes (CAPS). CAPS patients show IL-1beta-driven systemic inflammation together with non-histamine dependent urticarial rash, which are caused by activating mutations of the inflammasome, a multiprotein oligomer responsible for the initiation of inflammatory responses to pathogens. …

Title: OR11-005 - Mast cells respond to pathogen signals with IL-1ß
Authors: L Kraas
O Schmetzer
K Krause
E Latz
M Maurer
Publication date: 01-11-2013
Publisher: BioMed Central
Published in: Pediatric Rheumatology / Issue Special Issue 1/2013
Electronic ISSN: 1546-0096
DOI: https://doi.org/10.1186/1546-0096-11-S1-A194

At a glance: The STEP trials

Springer Medicine

OR11-005 - Mast cells respond to pathogen signals with IL-1ß

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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