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Journal of Cardiovascular Magnetic Resonance
Published in: Journal of Cardiovascular Magnetic Resonance 1/2016

Open Access 01-12-2016 | Walking poster presentation

Native T1 mapping versus CMR Feature Tracking (FT) derived strain analysis for the assessment of cardiac disease manifestation in Anderson Fabry

Authors: Anna B Reid, Christopher A Miller, Ana Jovanovic, Peter Woolfson, Nik Abidin, Richard P Steeds, James Moon, Matthias Schmitt

Published in: Journal of Cardiovascular Magnetic Resonance | Special Issue 1/2016

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Excerpt

Cardiovascular sequelae represent a leading cause of mortality in Fabry disease. Early detection of cardiac involvement is therefore a subject of considerable interest. Low native T1 values have been shown to be associated with echocardiographic markers of early systolic and diastolic dysfunction, even in those without left ventricular hypertrophy (LVH), and conceptually could be used to optimise the efficacy of Enzyme replacement therapy (ERT). The purpose of this study was to determine the relationship of both, native T1 and feature tracking CMR (FT-CMR) derived strain parameters, with maximal LV wall thickness and LVmass in Fabry's as a clinical marker of cardiac disease manifestation. …
Metadata
Title
Native T1 mapping versus CMR Feature Tracking (FT) derived strain analysis for the assessment of cardiac disease manifestation in Anderson Fabry
Authors
Anna B Reid
Christopher A Miller
Ana Jovanovic
Peter Woolfson
Nik Abidin
Richard P Steeds
James Moon
Matthias Schmitt
Publication date
01-12-2016
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1532-429X-18-S1-Q43

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