Published in:
Open Access
01-12-2015 | Poster presentation
Myocardial extracellular volume fraction and myocardial fibrosis by cmr in patients with severe aortic stenosis
Authors:
Gabriela Liberato, Juliana Bello, Rodrigo D Melo, Antonildes N Assunção Jr, Ariane B Pacheco, Breno A Soares, Debora Y Nakamura, Lea Demarchi, Victor E Costa, Roney O Sampaio, Roberto Kalil, Carlos E Rochitte
Published in:
Journal of Cardiovascular Magnetic Resonance
|
Special Issue 1/2015
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Excerpt
Severe aortic stenosis (AS) induces diffuse interstitial myocardial fibrosis (MF). CMR late gadolinium enhancement (LGE) technique is useful to detect focal MF. The amount of MF is associated with worse long-term prognosis after aortic valve replacement surgery (AVR). Measurements of T1 relaxation times before and after gadolinium administration allow determination of myocardial extracellular volume fraction (ECV) in order to assess diffuse MF. In this study we investigated ECV and LGE prevalence and extent in severe AS, and compare them to left ventricular (LV), aortic valve (AV) function and MF by biopsy. …
