Published in:
Open Access 01-01-2014 | Poster presentation
Differentiation of physiologic versus pathologic basal septal fibrosis: Proposed diagnostic criteria and associations with clinical and CMR-based markers of cardiovascular disease
Published in: Journal of Cardiovascular Magnetic Resonance | Special Issue 1/2014
Login to get accessExcerpt
Abnormal late gadolinium enhancement (LGE) is commonly identified in the basal septum of patients with dilated cardiomyopathy, hypertrophic cardiomyopathy and sarcoidosis, and has been associated with major adverse events. However, basal septal LGE may also be seen in otherwise normal individuals (Figure 1) and may be "physiologic". No diagnostic criteria to differentiate the latter have been established, and both its prevalence and clinical significance remain uncertain. In this study we propose such criteria and examine its prevalence and association with markers of cardiovascular disease.
Figure 1
(A) Apical long axis 3-chamber late gadolinium enhancement (LGE) image in a patient with "physiologic basal septal LGE" according to the criteria of; (1) direct contact with the aortic root, and (2) decreasing signal intensity apically. (B) Basal short axis view with mid myocardial late gadolinium enhancement.
× ![]()
…