Top

Journal of Cardiovascular Magnetic Resonance

Published in:

Open Access 01-01-2014 | Moderated poster presentation

Extracellular volume assessed by CMR T1-mapping correlates with histologically determined amount of diffuse fibrosis in DCM

Authors: Fabian aus dem Siepen, Sebastian Buss, Florian Andre, Marius Keller, Sebastian A Seitz, Grigorios Korosoglou, Evangelos Giannitsis, Hugo A Katus, Henning Steen

Published in: Journal of Cardiovascular Magnetic Resonance | Special Issue 1/2014

Excerpt

Diffuse myocardial fibrosis (MF) in dilated cardiomyopathy (DCM) is closely related to systolic and diastolic cardiac failure and could be identified as a major independent value prediciting clinical outcome. It results from elevated levels of collagen and is therefore associated with an expansion of the extracellular volume (ECV). Up to now, the detection of MF requires myocardial biopsy. Recent reports indicate that CMR T1-Mapping has the potential to detect MF non-invasively. We compared the ECV values derived from T1-mapping with the collagen volume fraction (CVF) as meausured in histological samples. …

Title: Extracellular volume assessed by CMR T1-mapping correlates with histologically determined amount of diffuse fibrosis in DCM
Authors: Fabian aus dem Siepen
Sebastian Buss
Florian Andre
Marius Keller
Sebastian A Seitz
Grigorios Korosoglou
Evangelos Giannitsis
Hugo A Katus
Henning Steen
Publication date: 01-01-2014
Publisher: BioMed Central
Published in: Journal of Cardiovascular Magnetic Resonance / Issue Special Issue 1/2014
Electronic ISSN: 1532-429X
DOI: https://doi.org/10.1186/1532-429X-16-S1-M8

At a glance: The STEP trials

Springer Medicine

Extracellular volume assessed by CMR T1-mapping correlates with histologically determined amount of diffuse fibrosis in DCM

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Special Issue 1/2014

Sub-30 ms real-time, free-breathing cardiac imaging with SPIRiT

Moderate intensity supine exercise causes decreased cardiac volumes and increased outer volume variations - a cardiac magnetic resonance imaging study

Scanner-efficient diffusion tensor imaging of human cardiac microstructure using the fast composite splitting reconstruction algorithm

Dependence of image quality of late gadolinium enhancement MRI of left atrium on number of patients imaged: results of multi-center trial DECAAF

Regions of latest mechanical contraction correspond to regions of latest electrical activation: an electro-mechanical coupling study in patients undergoing cardiac resynchronization therapy

Comparison of different T2* sequences with and without parallel imaging for the assessment of iron overload