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Journal of Cardiovascular Magnetic Resonance
Published in: Journal of Cardiovascular Magnetic Resonance 1/2012

Open Access 01-12-2012 | Research

Volumetric motion quantification by 3D tissue phase mapped CMR

Authors: Anja Lutz, Jan Paul, Axel Bornstedt, G Ulrich Nienhaus, Patrick Etyngier, Peter Bernhardt, Wolfgang Rottbauer, Volker Rasche

Published in: Journal of Cardiovascular Magnetic Resonance | Issue 1/2012

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Abstract

Background

The objective of this study was the quantification of myocardial motion from 3D tissue phase mapped (TPM) CMR. Recent work on myocardial motion quantification by TPM has been focussed on multi-slice 2D acquisitions thus excluding motion information from large regions of the left ventricle. Volumetric motion assessment appears an important next step towards the understanding of the volumetric myocardial motion and hence may further improve diagnosis and treatments in patients with myocardial motion abnormalities.

Methods

Volumetric motion quantification of the complete left ventricle was performed in 12 healthy volunteers and two patients applying a black-blood 3D TPM sequence. The resulting motion field was analysed regarding motion pattern differences between apical and basal locations as well as for asynchronous motion pattern between different myocardial segments in one or more slices. Motion quantification included velocity, torsion, rotation angle and strain derived parameters.

Results

All investigated motion quantification parameters could be calculated from the 3D-TPM data. Parameters quantifying hypokinetic or asynchronous motion demonstrated differences between motion impaired and healthy myocardium.

Conclusions

3D-TPM enables the gapless volumetric quantification of motion abnormalities of the left ventricle, which can be applied in future application as additional information to provide a more detailed analysis of the left ventricular function.
Appendix
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Metadata
Title
Volumetric motion quantification by 3D tissue phase mapped CMR
Authors
Anja Lutz
Jan Paul
Axel Bornstedt
G Ulrich Nienhaus
Patrick Etyngier
Peter Bernhardt
Wolfgang Rottbauer
Volker Rasche
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Journal of Cardiovascular Magnetic Resonance / Issue 1/2012
Electronic ISSN: 1532-429X
DOI
https://doi.org/10.1186/1532-429X-14-74

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