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Published in: Cost Effectiveness and Resource Allocation 1/2013

Open Access 01-12-2013 | Research

WTP for a QALY and health states: More money for severer health states?

Authors: Takeru Shiroiwa, Ataru Igarashi, Takashi Fukuda, Shunya Ikeda

Published in: Cost Effectiveness and Resource Allocation | Issue 1/2013

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Abstract

Background

In economic evaluation, cost per quality-adjusted life year (QALY) is generally used as an indicator for cost-effectiveness. Although JPY 5 million to 6 million (USD 60, 000 to 75,000) per QALY is frequently referred to as a threshold in Japan, do all QALYs have the same monetary value?

Methods

To examine the relationship between severity of health status and monetary value of a QALY, we obtained willingness to pay (WTP) values for one additional QALY in eight patterns of health states. We randomly sampled approximately 2,400 respondents from an online panel. To avoid misunderstanding, we randomly allocated respondents to one of 16 questionnaires, with 250 responses expected for each pattern. After respondents were asked whether they wanted to purchase the treatment, double-bounded dichotomous choice method was used to obtain WTP values.

Results

The results clearly show that the WTP per QALY is higher for worse health states than for better health states. The slope was about JPY −1 million per 0.1 utility score increase. The mean and median WTP values per QALY for 16 health states were JPY 5 million, consistent with our previous survey. For respondents who wanted to purchase the treatment, WTP values were significantly correlated with household income.

Conclusion

This survey shows that QALY based on the EQ-5D does not necessarily have the same monetary value. The WTP per QALY should range from JPY 2 million (USD 20,000) to JPY 8 million (USD 80,000), corresponding to the severity of health states.
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Literature
1.
go back to reference Drummond MF, Sculpher MJ, Torrance GW, O'Brien B, Stoddart GL: Methods for the economic evaluation of health care progrmmes 3rd edition. Oxford: Oxford university press; 2005. Drummond MF, Sculpher MJ, Torrance GW, O'Brien B, Stoddart GL: Methods for the economic evaluation of health care progrmmes 3rd edition. Oxford: Oxford university press; 2005.
2.
go back to reference Gold MR, Siegel JE, Russell LB, Weinstein MC: Cost-effectiveness in health and medicine. New York: Oxford University Press; 1996. Gold MR, Siegel JE, Russell LB, Weinstein MC: Cost-effectiveness in health and medicine. New York: Oxford University Press; 1996.
3.
go back to reference Weinstein MC: A QALY is a QALY is a QALY - or Is It? J Health Econ 1988, 7(3):289–290. 10.1016/0167-6296(88)90030-6CrossRefPubMed Weinstein MC: A QALY is a QALY is a QALY - or Is It? J Health Econ 1988, 7(3):289–290. 10.1016/0167-6296(88)90030-6CrossRefPubMed
4.
go back to reference Dolan P, Shaw R, Tsuchiya A, et al.: QALY maximisation and people's preferences: a methodological review of the literature. Health Econ 2005, 14(2):197–208. 10.1002/hec.924CrossRefPubMed Dolan P, Shaw R, Tsuchiya A, et al.: QALY maximisation and people's preferences: a methodological review of the literature. Health Econ 2005, 14(2):197–208. 10.1002/hec.924CrossRefPubMed
5.
go back to reference Institute for Health and Clinical Excellence: Guide to the methods of technology appraisal. 2008. Institute for Health and Clinical Excellence: Guide to the methods of technology appraisal. 2008.
6.
go back to reference Department of health: A new value-based approach to the pricing of branded medicines. 2010. Department of health: A new value-based approach to the pricing of branded medicines. 2010.
7.
go back to reference Shah KK: Severity of illness and priority setting in healthcare: a review of the literature. Health Policy 2009, 93(2–3):77–84.CrossRefPubMed Shah KK: Severity of illness and priority setting in healthcare: a review of the literature. Health Policy 2009, 93(2–3):77–84.CrossRefPubMed
8.
go back to reference Nord E, Pinto JL, Richardson J, et al.: Incorporating societal concerns for fairness in numerical valuations of health programmes. Health Econ 1999, 8(1):25–39. 10.1002/(SICI)1099-1050(199902)8:1<25::AID-HEC398>3.0.CO;2-HCrossRefPubMed Nord E, Pinto JL, Richardson J, et al.: Incorporating societal concerns for fairness in numerical valuations of health programmes. Health Econ 1999, 8(1):25–39. 10.1002/(SICI)1099-1050(199902)8:1<25::AID-HEC398>3.0.CO;2-HCrossRefPubMed
9.
go back to reference Shiroiwa T, Sung YK, Fukuda T, et al.: International survey on willingness-to-pay (WTP) for one additional QALY gained: what is the threshold of cost effectiveness? Health Econ 2010, 19(4):422–437. 10.1002/hec.1481CrossRefPubMed Shiroiwa T, Sung YK, Fukuda T, et al.: International survey on willingness-to-pay (WTP) for one additional QALY gained: what is the threshold of cost effectiveness? Health Econ 2010, 19(4):422–437. 10.1002/hec.1481CrossRefPubMed
10.
go back to reference Donaldson C, Baker R, Mason H, et al.: The social value of a QALY: raising the bar or barring the raise? BMC Health Serv Res 2011, 11: 8. 10.1186/1472-6963-11-8PubMedCentralCrossRefPubMed Donaldson C, Baker R, Mason H, et al.: The social value of a QALY: raising the bar or barring the raise? BMC Health Serv Res 2011, 11: 8. 10.1186/1472-6963-11-8PubMedCentralCrossRefPubMed
11.
go back to reference Baker R, Bateman I, Donaldson C, et al.: Weighting and valuing quality-adjusted life-years using stated preference methods: preliminary results from the Social Value of a QALY Project. Health Technol Assess 2010, 14(27):1–162.CrossRef Baker R, Bateman I, Donaldson C, et al.: Weighting and valuing quality-adjusted life-years using stated preference methods: preliminary results from the Social Value of a QALY Project. Health Technol Assess 2010, 14(27):1–162.CrossRef
12.
go back to reference Robinson A, Gyrd-Hansen D, Bacon P, et al.: Estimating a WTP-based value of a QALY: The 'chained' approach. Soc Sci Med 2013, 92: 92–104.CrossRefPubMed Robinson A, Gyrd-Hansen D, Bacon P, et al.: Estimating a WTP-based value of a QALY: The 'chained' approach. Soc Sci Med 2013, 92: 92–104.CrossRefPubMed
13.
go back to reference Arrow K, Solow R, Portney PR, et al.: Report of the NOAA Panel on Contingent Valuation. 1993. Arrow K, Solow R, Portney PR, et al.: Report of the NOAA Panel on Contingent Valuation. 1993.
14.
go back to reference Turnbull BW: The empirical distribution function from arbitarily grouped, censored and truncated data. J Roy Stat Soc B. 1976, 38: 290–295. Turnbull BW: The empirical distribution function from arbitarily grouped, censored and truncated data. J Roy Stat Soc B. 1976, 38: 290–295.
15.
go back to reference Ministry of Health, Labour and Welfare. National livelihood survey; 2009. Ministry of Health, Labour and Welfare. National livelihood survey; 2009.
16.
go back to reference Ministry of Health, Labour and Welfare. Population survey; 2010. Ministry of Health, Labour and Welfare. Population survey; 2010.
17.
go back to reference Organisation for Economic Co-operation and Development. Education at a Glance; 2011. Organisation for Economic Co-operation and Development. Education at a Glance; 2011.
18.
go back to reference College voor Zorgverzekeringen: College voor Zorgverzekeringen. Pakketbeheer in de praktijk; 2006. College voor Zorgverzekeringen: College voor Zorgverzekeringen. Pakketbeheer in de praktijk; 2006.
19.
go back to reference Williams A: Intergenerational equity: an exploration of the 'fair innings' argument. Health Econ 1997, 6(2):117–132. 10.1002/(SICI)1099-1050(199703)6:2<117::AID-HEC256>3.0.CO;2-BCrossRefPubMed Williams A: Intergenerational equity: an exploration of the 'fair innings' argument. Health Econ 1997, 6(2):117–132. 10.1002/(SICI)1099-1050(199703)6:2<117::AID-HEC256>3.0.CO;2-BCrossRefPubMed
20.
go back to reference Stolk EA, van Donselaar G, Brouwer WB, Busschbach JJ: Reconciliation of economic concerns and health policy: illustration of an equity adjustment procedure using proportional shortfall. Pharmacoeconomics 2004, 22(17):1097–1107. 10.2165/00019053-200422170-00001CrossRefPubMed Stolk EA, van Donselaar G, Brouwer WB, Busschbach JJ: Reconciliation of economic concerns and health policy: illustration of an equity adjustment procedure using proportional shortfall. Pharmacoeconomics 2004, 22(17):1097–1107. 10.2165/00019053-200422170-00001CrossRefPubMed
21.
go back to reference NICE: Guide to the methods of technology appraisal. 2008. NICE: Guide to the methods of technology appraisal. 2008.
22.
go back to reference CADTH: Guidelines for the economic evaluation of health technologies. 2006. CADTH: Guidelines for the economic evaluation of health technologies. 2006.
23.
go back to reference National institute for Health and Clinical Excellence: Appraising life-extending, end of life treatments. 2009. National institute for Health and Clinical Excellence: Appraising life-extending, end of life treatments. 2009.
24.
go back to reference Gyrd-Hansen D: Willingness to pay for a QALY. Health Econ 2003, 12(12):1049–1060. 10.1002/hec.799CrossRefPubMed Gyrd-Hansen D: Willingness to pay for a QALY. Health Econ 2003, 12(12):1049–1060. 10.1002/hec.799CrossRefPubMed
25.
go back to reference Bobinac A, Van Exel NJ, Rutten FF, Brouwer WB: Willingness to pay for a quality-adjusted life-year: the individual perspective. Value Health 2010, 13(8):1046–1055. 10.1111/j.1524-4733.2010.00781.xCrossRefPubMed Bobinac A, Van Exel NJ, Rutten FF, Brouwer WB: Willingness to pay for a quality-adjusted life-year: the individual perspective. Value Health 2010, 13(8):1046–1055. 10.1111/j.1524-4733.2010.00781.xCrossRefPubMed
26.
go back to reference King JT Jr, Tsevat J, Lave JR, Roberts MS: Willingness to pay for a quality-adjusted life year: implications for societal health care resource allocation. Med Decis Making 2005, 25(6):667–677. 10.1177/0272989X05282640CrossRefPubMed King JT Jr, Tsevat J, Lave JR, Roberts MS: Willingness to pay for a quality-adjusted life year: implications for societal health care resource allocation. Med Decis Making 2005, 25(6):667–677. 10.1177/0272989X05282640CrossRefPubMed
27.
go back to reference Rawlins M, Barnett D, Stevens A: Pharmacoeconomics: NICE's approach to decision-making. Br J Clin Pharmacol 2010, 70(3):346–349. 10.1111/j.1365-2125.2009.03589.xPubMedCentralCrossRefPubMed Rawlins M, Barnett D, Stevens A: Pharmacoeconomics: NICE's approach to decision-making. Br J Clin Pharmacol 2010, 70(3):346–349. 10.1111/j.1365-2125.2009.03589.xPubMedCentralCrossRefPubMed
Metadata
Title
WTP for a QALY and health states: More money for severer health states?
Authors
Takeru Shiroiwa
Ataru Igarashi
Takashi Fukuda
Shunya Ikeda
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Cost Effectiveness and Resource Allocation / Issue 1/2013
Electronic ISSN: 1478-7547
DOI
https://doi.org/10.1186/1478-7547-11-22

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