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Open Access 01-12-2003 | Review

Tolerance of the fetus by the maternal immune system: role of inflammatory mediators at the feto-maternal interface

Authors: Colette Kanellopoulos-Langevin, Stéphane M Caucheteux, Philippe Verbeke, David M Ojcius

Published in: Reproductive Biology and Endocrinology | Issue 1/2003

Abstract

The adaptive immune system of placental mammals has evolved to tolerate the fetus. Rejection of the fetus by adaptive immune responses is therefore a rare event, with abortion being caused more frequently by inflammation in the placenta. This review will cover recent aspects of immune privilege and the innate immune system at the feto-maternal interface, citing examples of the role played by microbial infections in fetal demise.

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Title: Tolerance of the fetus by the maternal immune system: role of inflammatory mediators at the feto-maternal interface
Authors: Colette Kanellopoulos-Langevin
Stéphane M Caucheteux
Philippe Verbeke
David M Ojcius
Publication date: 01-12-2003
Publisher: BioMed Central
Published in: Reproductive Biology and Endocrinology / Issue 1/2003
Electronic ISSN: 1477-7827
DOI: https://doi.org/10.1186/1477-7827-1-121

At a glance: The STEP trials

Springer Medicine

Tolerance of the fetus by the maternal immune system: role of inflammatory mediators at the feto-maternal interface

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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