Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2010

Open Access 01-12-2010 | Research

Development of the ATAQ-IPF: a tool to assess quality of life in IPF

Authors: Jeffrey J Swigris, Sandra R Wilson, Kathy E Green, David B Sprunger, Kevin K Brown, Frederick S Wamboldt

Published in: Health and Quality of Life Outcomes | Issue 1/2010

Login to get access

Abstract

Background

There is no disease-specific instrument to assess health-related quality of life (HRQL) in patients with idiopathic pulmonary fibrosis (IPF).

Methods

Patients' perspectives were collected to develop domains and items for an IPF-specific HRQL instrument. We used item variance and Rasch analysis to construct the ATAQ-IPF (A Tool to Assess Quality of life in IPF).

Results

The ATAQ-IPF version 1 is composed of 74 items comprising 13 domains. All items fit the Rasch model. Domains and the total instrument possess acceptable psychometric characteristics for a multidimensional questionnaire. The pattern of correlations between ATAQ-IPF scores and physiologic variables known to be important in IPF, along with significant differences in ATAQ-IPF scores between subjects using versus those not using supplemental oxygen, support its validity.

Conclusions

Patient-centered and careful statistical methodologies were used to construct the ATAQ-IPF version 1, an IPF-specific HRQL instrument. Simple summation scoring is used to derive individual domain scores as well as a total score. Results support the validity of the ATAQ-IPF, and future studies will build on that validity.
Appendix
Available only for authorised users
Literature
1.
Guyatt G, Walter S, Norman G: Measuring change over time: assessing the usefulness of evaluative instruments. J Chronic Dis 1987, 40: 171–178. 10.1016/0021-9681(87)90069-5PubMedCrossRef
2.
Jones PW, Harding G, Berry P, Wiklund I, Chen WH, Kline Leidy N: Development and first validation of the COPD Assessment Test. Eur Respir J 2009, 34: 648–654. 10.1183/09031936.00102509PubMedCrossRef
3.
Meguro M, Barley EA, Spencer S, Jones PW: Development and Validation of an Improved, COPD-Specific Version of the St. George Respiratory Questionnaire. Chest 2007, 132: 456–463. 10.1378/chest.06-0702PubMedCrossRef
4.
Juniper EF, O'Byrne PM, Guyatt GH, Ferrie PJ, King DR: Development and validation of a questionnaire to measure asthma control. Eur Respir J 1999, 14: 902–907. 10.1034/j.1399-3003.1999.14d29.xPubMedCrossRef
5.
Hyland ME, Finnis S, Irvine SH: A scale for assessing quality of life in adult asthma sufferers. J Psychosom Res 1991, 35: 99–110. 10.1016/0022-3999(91)90011-CPubMedCrossRef
6.
American Thoracic Society: Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am J Respir Crit Care Med 2000, 161: 646–664.CrossRef
7.
Olson AL, Swigris JJ, Lezotte DC, Norris JM, Wilson CG, Brown KK: Mortality from pulmonary fibrosis increased in the United States from 1992 to 2003. Am J Respir Crit Care Med 2007, 176: 277–284. 10.1164/rccm.200701-044OCPubMedCrossRef
8.
Swigris JJ, Gould MK, Wilson SR: Health-related quality of life among patients with idiopathic pulmonary fibrosis. Chest 2005, 127: 284–294. 10.1378/chest.127.1.284PubMedCrossRef
9.
Swigris JJ, Kuschner WG, Jacobs SS, Wilson SR, Gould MK: Health-related quality of life in patients with idiopathic pulmonary fibrosis: a systematic review. Thorax 2005, 60: 588–594. 10.1136/thx.2004.035220PubMedCentralPubMedCrossRef
10.
Swigris JJ, Stewart AL, Gould MK, Wilson SR: Patients' perspectives on how idiopathic pulmonary fibrosis affects the quality of their lives. Health Qual Life Outcomes 2005, 3: 61. 10.1186/1477-7525-3-61PubMedCentralPubMedCrossRef
11.
Rasch G: Probabilistic models for some intelligence and attainment tests. Danish Institute of Educational Research 1960.
12.
Bond T, Fox C: Applying the Rasch Model: Fundamental Measurement in the Human Sciences. Mahway, New Jersey: Lawrence Erlbaum Associates; 2007.
13.
Linacre J: What do Infit and Outfit, Mean-square and Standardized mean? Rasch Measurement Transactions 2002, 16: 878.
14.
Cronbach L: Coefficient alpha and the internal structure of tests. Psychometrika 1951, 22: 293–296.
15.
Streiner D, Norman G: Health Measurement Scales: A practical guide to their development and use. Fourth edition. New York: Oxford University Press; 2008.CrossRef
16.
Nunnally J: Psychometric Theory. New York: McGraw-Hill; 1978.
17.
American Thoracic Society: Lung function testing: selection of reference values and interpretative strategies. Am Rev Respir Dis 1991, 144: 1202–1218.CrossRef
18.
American Thoracic Society: Standardization of spirometry, 1994 update. Am J Respir Crit Care Med 1995, 152: 1107–1136.CrossRef
19.
Swigris JJ, Swick J, Wamboldt FS, et al.: Heart Rate Recovery After 6-Minute Walk Test Predicts Survival in Patients With Idiopathic Pulmonary Fibrosis. Chest 2009, 136: 841–848. 10.1378/chest.09-0211PubMedCentralPubMedCrossRef
20.
Linacre J: Measurement, Meaning and Mortality. Pacific Rim Objective Measurement Symposium and International Symposium on Measurement and Evaluation. Kuala Lumpur, Malaysia 2005.
21.
Metadata
Title
Development of the ATAQ-IPF: a tool to assess quality of life in IPF
Authors
Jeffrey J Swigris
Sandra R Wilson
Kathy E Green
David B Sprunger
Kevin K Brown
Frederick S Wamboldt
Publication date
01-12-2010
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2010
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/1477-7525-8-77

Other articles of this Issue 1/2010

Health and Quality of Life Outcomes 1/2010 Go to the issue

Research

Reliability of 95% confidence interval revealed by expected quality-of-life scores: an example of nasopharyngeal carcinoma patients after radiotherapy using EORTC QLQ-C 30

Research

Coping flexibility in college students with depressive symptoms

Research

Evaluation of internal reliability in the presence of inconsistent responses

Research

Clinical and psychological correlates of health-related quality of life in obese patients

Research

Effects of mode of administration (MOA) on the measurement properties of the EORTC QLQ-C30: a randomized study

Research

The psychological burden of an initially unexplained illness: patients with sternocostoclavicular hyperostosis before and after delayed diagnosis