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Health and Quality of Life Outcomes

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Open Access 01-12-2010 | Research

Anxiety and depression in association with morbid obesity: changes with improved physical health after duodenal switch

Authors: John Roger Andersen, Anny Aasprang, Per Bergsholm, Nils Sletteskog, Villy Våge, Gerd Karin Natvig

Published in: Health and Quality of Life Outcomes | Issue 1/2010

Abstract

Background

Patients with morbid obesity have an increased risk for anxiety and depression. The "duodenal switch" is perhaps the most effective obesity surgery procedure for inducing weight loss. However, to our knowledge, data on symptoms of anxiety and depression after the duodenal switch are lacking. Furthermore, it has been hypothesized that self-reported physical health is the major predictor of symptoms of depression in patients with morbid obesity. We therefore investigated the symptoms of anxiety and depression before and after the duodenal switch procedure and whether post-operative changes in self-reported physical health were predictive of changes in these symptoms.

Methods

Data were assessed before surgery (n = 50), and one (n = 47) and two (n = 44) years afterwards. Symptoms of anxiety and depression were assessed by the "Hospital Anxiety and Depression Scale", and self-reported physical health was assessed by the "Short-Form 36" questionnaire. Linear mixed effect models were used to investigate changes in the symptoms of anxiety and depression. Correlation and linear multiple regression analyses were used to study whether changes in self-reported physical health were predictive of post-operative changes in the symptoms of anxiety and depression.

Results

The symptom burden of anxiety and depression were high before surgery but were normalized one and two years afterwards (P < 0.001). The degree of improvement in self-reported physical health was associated with statistically significant reductions in the symptoms of anxiety (P = 0.003) and depression (P = 0.004).

Conclusions

The novelty of this study is the large and sustained reductions in the symptoms of anxiety and depression after the duodenal switch procedure, and that these changes were closely associated with improvements in self-reported physical health.

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Title: Anxiety and depression in association with morbid obesity: changes with improved physical health after duodenal switch
Authors: John Roger Andersen
Anny Aasprang
Per Bergsholm
Nils Sletteskog
Villy Våge
Gerd Karin Natvig
Publication date: 01-12-2010
Publisher: BioMed Central
Published in: Health and Quality of Life Outcomes / Issue 1/2010
Electronic ISSN: 1477-7525
DOI: https://doi.org/10.1186/1477-7525-8-52

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Anxiety and depression in association with morbid obesity: changes with improved physical health after duodenal switch

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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