Skip to main content
Top
Published in: Health and Quality of Life Outcomes 1/2010

Open Access 01-12-2010 | Research

A Rasch and confirmatory factor analysis of the General Health Questionnaire (GHQ) - 12

Authors: Adam B Smith, Lesley J Fallowfield, Dan P Stark, Galina Velikova, Valerie Jenkins

Published in: Health and Quality of Life Outcomes | Issue 1/2010

Login to get access

Abstract

Background

The General Health Questionnaire (GHQ) - 12 was designed as a short questionnaire to assess psychiatric morbidity. Despite the fact that studies have suggested a number of competing multidimensional factor structures, it continues to be largely used as a unidimensional instrument. This may have an impact on the identification of psychiatric morbidity in target populations. The aim of this study was to explore the dimensionality of the GHQ-12 and to evaluate a number of alternative models for the instrument.

Methods

The data were drawn from a large heterogeneous sample of cancer patients. The Partial Credit Model (Rasch) was applied to the 12-item GHQ. Item misfit (infit mean square ≥ 1.3) was identified, misfitting items removed and unidimensionality and differential item functioning (age, gender, and treatment aims) were assessed. The factor structures of the various alternative models proposed in the literature were explored and optimum model fit evaluated using Confirmatory Factor Analysis.

Results

The Rasch analysis of the 12-item GHQ identified six misfitting items. Removal of these items produced a six-item instrument which was not unidimensional. The Rasch analysis of an 8-item GHQ demonstrated two unidimensional structures corresponding to Anxiety/Depression and Social Dysfunction. No significant differential item functioning was observed by age, gender and treatment aims for the six- and eight-item GHQ. Two models competed for best fit from the confirmatory factor analysis, namely the GHQ-8 and Hankin's (2008) unidimensional model, however, the GHQ-8 produced the best overall fit statistics.

Conclusions

The results are consistent with the evidence that the GHQ-12 is a multi-dimensional instrument. Use of the summated scores for the GHQ-12 could potentially lead to an incorrect assessment of patients' psychiatric morbidity. Further evaluation of the GHQ-12 with different target populations is warranted.
Appendix
Available only for authorised users
Literature
1.
go back to reference Goldberg D, Williams P: A User's Guide to the General Health Questionnaire. Windsor: NFER-Nelson; 1988. Goldberg D, Williams P: A User's Guide to the General Health Questionnaire. Windsor: NFER-Nelson; 1988.
2.
go back to reference Goldberg DP, Hillier VF: A scaled version of the General Health Questionnaire. Psychol Med 1979, 9: 139–145. 10.1017/S0033291700021644PubMedCrossRef Goldberg DP, Hillier VF: A scaled version of the General Health Questionnaire. Psychol Med 1979, 9: 139–145. 10.1017/S0033291700021644PubMedCrossRef
3.
go back to reference Werneke U, Goldberg DP, Yalcin I, Üstün BT: The stability of the factor structure of the General Health Questionnaire. Psychol Med 2000, 30: 823–829. 10.1017/S0033291799002287PubMedCrossRef Werneke U, Goldberg DP, Yalcin I, Üstün BT: The stability of the factor structure of the General Health Questionnaire. Psychol Med 2000, 30: 823–829. 10.1017/S0033291799002287PubMedCrossRef
4.
go back to reference Politi PL, Piccinelli M, Wilkinson G: Reliability, validity & factor structure of the 12-item General Health Questionnaire among young males in Italy. Acta Psychiatr Scand 1994, 90: 432–437. 10.1111/j.1600-0447.1994.tb01620.xPubMedCrossRef Politi PL, Piccinelli M, Wilkinson G: Reliability, validity & factor structure of the 12-item General Health Questionnaire among young males in Italy. Acta Psychiatr Scand 1994, 90: 432–437. 10.1111/j.1600-0447.1994.tb01620.xPubMedCrossRef
5.
go back to reference KiliÇ C, Rezaki M, Rezaki B, Kaplan I, Özgen G: General Health Questionnaire (GHQ12 & GHQ28): psychometric properties and factor structure of the scales in a Turkish primary care sample. Soc Psychiatry Psychiatr Epidemiol 1997, 32: 327–331. 10.1007/BF00805437PubMedCrossRef KiliÇ C, Rezaki M, Rezaki B, Kaplan I, Özgen G: General Health Questionnaire (GHQ12 & GHQ28): psychometric properties and factor structure of the scales in a Turkish primary care sample. Soc Psychiatry Psychiatr Epidemiol 1997, 32: 327–331. 10.1007/BF00805437PubMedCrossRef
6.
go back to reference Schmitz N, Kruse J, Tress W: Psychometric properties of the General Health Questionnaire (GHQ-12) in a German primary care sample. Acta Psychiatr Scand 1999, 100: 462–468. 10.1111/j.1600-0447.1999.tb10898.xPubMedCrossRef Schmitz N, Kruse J, Tress W: Psychometric properties of the General Health Questionnaire (GHQ-12) in a German primary care sample. Acta Psychiatr Scand 1999, 100: 462–468. 10.1111/j.1600-0447.1999.tb10898.xPubMedCrossRef
7.
go back to reference Gureje O: Reliability and the factor structure of the Yoruba version of the 12-item General Health Questionnaire. Acta Psychiatr Scand 1991, 84: 125–129. 10.1111/j.1600-0447.1991.tb03115.xPubMedCrossRef Gureje O: Reliability and the factor structure of the Yoruba version of the 12-item General Health Questionnaire. Acta Psychiatr Scand 1991, 84: 125–129. 10.1111/j.1600-0447.1991.tb03115.xPubMedCrossRef
8.
go back to reference Martin AJ: Assessing the multidimensionality of the 12-item General Health Questionnaire. Psychol Rep 1999, 84: 927–935. 10.2466/PR0.84.3.927-935PubMedCrossRef Martin AJ: Assessing the multidimensionality of the 12-item General Health Questionnaire. Psychol Rep 1999, 84: 927–935. 10.2466/PR0.84.3.927-935PubMedCrossRef
9.
go back to reference Picardi A, Abeni D, Pasquini P: Assessing psychological distress in patients with skin diseases: reliability, validity and factor structure of the GHQ - 12. J Eur Acad Dermatol Venereol 2001, 15: 410–417. 10.1046/j.1468-3083.2001.00336.xPubMedCrossRef Picardi A, Abeni D, Pasquini P: Assessing psychological distress in patients with skin diseases: reliability, validity and factor structure of the GHQ - 12. J Eur Acad Dermatol Venereol 2001, 15: 410–417. 10.1046/j.1468-3083.2001.00336.xPubMedCrossRef
10.
go back to reference Campbell A, Walker J, Farrell G: Confirmatory factor analysis of the GHQ12: Can I see that again? Aust New Zeal J Psychiatr 2003, 37: 475–483. 10.1046/j.1440-1614.2003.01208.xCrossRef Campbell A, Walker J, Farrell G: Confirmatory factor analysis of the GHQ12: Can I see that again? Aust New Zeal J Psychiatr 2003, 37: 475–483. 10.1046/j.1440-1614.2003.01208.xCrossRef
11.
go back to reference Worsely A, Gribbin CC: A factor analytic study of the twelve-item General Health Questionnaire. Aust New Zeal J Psychiatr 1977, 11: 269–272. 10.3109/00048677709159577CrossRef Worsely A, Gribbin CC: A factor analytic study of the twelve-item General Health Questionnaire. Aust New Zeal J Psychiatr 1977, 11: 269–272. 10.3109/00048677709159577CrossRef
12.
go back to reference Graetz B: Multidimensional properties of the 12-item General Health Questionnaire. Soc Psychiatry Psychiatr Epidemiol 1991, 26: 132–138. 10.1007/BF00782952PubMedCrossRef Graetz B: Multidimensional properties of the 12-item General Health Questionnaire. Soc Psychiatry Psychiatr Epidemiol 1991, 26: 132–138. 10.1007/BF00782952PubMedCrossRef
13.
go back to reference Cheung YB: A confirmatory factor analysis of the 12-item General Health Questionnaire among older people. Int J Geriatr Psychiatr 2002, 17: 739–744. 10.1002/gps.693CrossRef Cheung YB: A confirmatory factor analysis of the 12-item General Health Questionnaire among older people. Int J Geriatr Psychiatr 2002, 17: 739–744. 10.1002/gps.693CrossRef
14.
go back to reference Gao F, Luo N, Thumboo J, Fones C, Li SC, Cheung YB: Does the 12-item General Health Questionnaire contain multiple factors and do we need them? Health Qual Life Outcomes 2004, 2: 63. 10.1186/1477-7525-2-63PubMedCentralPubMedCrossRef Gao F, Luo N, Thumboo J, Fones C, Li SC, Cheung YB: Does the 12-item General Health Questionnaire contain multiple factors and do we need them? Health Qual Life Outcomes 2004, 2: 63. 10.1186/1477-7525-2-63PubMedCentralPubMedCrossRef
15.
go back to reference Shevlin M, Adamson G: Alternative factor models and factorial invariance of the GHQ-12: a large sample analysis using confirmatory factor analysis. Psychol Assess 2005, 17: 231–236. 10.1037/1040-3590.17.2.231PubMedCrossRef Shevlin M, Adamson G: Alternative factor models and factorial invariance of the GHQ-12: a large sample analysis using confirmatory factor analysis. Psychol Assess 2005, 17: 231–236. 10.1037/1040-3590.17.2.231PubMedCrossRef
16.
go back to reference Mäkikangas A, Feldt T, Kinnunen U, Tolvanen A, Kinnunen ML, Pulkkinen L: The factor structure and factorial invariance of the 12-item General Health Questionnaire (GHQ-12) across time: Evidence from two community-based samples. Psychol Assess 2006, 18: 444–451. 10.1037/1040-3590.18.4.444PubMedCrossRef Mäkikangas A, Feldt T, Kinnunen U, Tolvanen A, Kinnunen ML, Pulkkinen L: The factor structure and factorial invariance of the 12-item General Health Questionnaire (GHQ-12) across time: Evidence from two community-based samples. Psychol Assess 2006, 18: 444–451. 10.1037/1040-3590.18.4.444PubMedCrossRef
17.
go back to reference Penninkilampi-Kerola V, Miettunen J, Ebeling H: A comparative assessment of the factor structures and psychometric properties of the GHQ-12 and the GHQ-20 based on data from a Finnish population-based sample. Scand J Psychol 2006, 47: 431–440. 10.1111/j.1467-9450.2006.00551.xPubMedCrossRef Penninkilampi-Kerola V, Miettunen J, Ebeling H: A comparative assessment of the factor structures and psychometric properties of the GHQ-12 and the GHQ-20 based on data from a Finnish population-based sample. Scand J Psychol 2006, 47: 431–440. 10.1111/j.1467-9450.2006.00551.xPubMedCrossRef
18.
go back to reference Kalliath TJ, O'Driscoll MP, Brough P: A confirmatory factor analysis of the General Health Questionnaire-12. Stress Health 2004, 20: 11–20. 10.1002/smi.993CrossRef Kalliath TJ, O'Driscoll MP, Brough P: A confirmatory factor analysis of the General Health Questionnaire-12. Stress Health 2004, 20: 11–20. 10.1002/smi.993CrossRef
19.
go back to reference French DJ, Tait RJ: Measurement invariance in the General Health Questionnaire-12 in young Australian adolescents. Eur Child Adol Psychiatr 2004, 13: 1–7. 10.1007/s00787-004-0345-7CrossRef French DJ, Tait RJ: Measurement invariance in the General Health Questionnaire-12 in young Australian adolescents. Eur Child Adol Psychiatr 2004, 13: 1–7. 10.1007/s00787-004-0345-7CrossRef
20.
go back to reference Stucki G, Daltroy L, Katz JN, Johannesson M, Liang MH: Interpretation of change scores in ordinal clinical scales and health status measures: the whole may not equal the sum of the parts. J Clin Epidemiol 1996, 49: 711–717. 10.1016/0895-4356(96)00016-9PubMedCrossRef Stucki G, Daltroy L, Katz JN, Johannesson M, Liang MH: Interpretation of change scores in ordinal clinical scales and health status measures: the whole may not equal the sum of the parts. J Clin Epidemiol 1996, 49: 711–717. 10.1016/0895-4356(96)00016-9PubMedCrossRef
21.
go back to reference Andrich D, Van Schoubroeck L: The General Health Questionnaire: A psychometric analysis using latent trait theory. Psychol Med 1989, 19: 469–485. 10.1017/S0033291700012502PubMedCrossRef Andrich D, Van Schoubroeck L: The General Health Questionnaire: A psychometric analysis using latent trait theory. Psychol Med 1989, 19: 469–485. 10.1017/S0033291700012502PubMedCrossRef
22.
go back to reference Hankins M: The factor structure of the twelve item General Health Questionnaire (GHQ-12): the result of negative phrasing? Clin Practice Epidemiol Mental Health 2008, 4: 10. 10.1186/1745-0179-4-10CrossRef Hankins M: The factor structure of the twelve item General Health Questionnaire (GHQ-12): the result of negative phrasing? Clin Practice Epidemiol Mental Health 2008, 4: 10. 10.1186/1745-0179-4-10CrossRef
23.
go back to reference Jenkins V, Fallowfield LJ, Saul J: Information needs of patients with cancer: results from a large study in UK cancer centres. Br J Cancer 2001, 84: 48–51. 10.1054/bjoc.2000.1573PubMedCentralPubMedCrossRef Jenkins V, Fallowfield LJ, Saul J: Information needs of patients with cancer: results from a large study in UK cancer centres. Br J Cancer 2001, 84: 48–51. 10.1054/bjoc.2000.1573PubMedCentralPubMedCrossRef
24.
go back to reference Fallowfield LJ, Jenkins V, Farewell V, Saul J, Duffy A, Eves R: Efficacy of a Cancer Research UK communications skills training model for oncologists: A randomised controlled trial. Lancet 2002, 359: 650–656. 10.1016/S0140-6736(02)07810-8PubMedCrossRef Fallowfield LJ, Jenkins V, Farewell V, Saul J, Duffy A, Eves R: Efficacy of a Cancer Research UK communications skills training model for oncologists: A randomised controlled trial. Lancet 2002, 359: 650–656. 10.1016/S0140-6736(02)07810-8PubMedCrossRef
25.
go back to reference Fallowfield LJ, Ratcliffe D, Jenkins V, Saul J: Psychiatric morbidity and its recognition by doctors in patients with cancer. Br J Cancer 2001, 84: 1011–1015. 10.1054/bjoc.2001.1724PubMedCentralPubMedCrossRef Fallowfield LJ, Ratcliffe D, Jenkins V, Saul J: Psychiatric morbidity and its recognition by doctors in patients with cancer. Br J Cancer 2001, 84: 1011–1015. 10.1054/bjoc.2001.1724PubMedCentralPubMedCrossRef
26.
go back to reference Goodchild ME, Duncan-Jones P: Chronicity and the General Health Questionnaire. Br J Psychiatr 1985, 146: 55–61. 10.1192/bjp.146.1.55CrossRef Goodchild ME, Duncan-Jones P: Chronicity and the General Health Questionnaire. Br J Psychiatr 1985, 146: 55–61. 10.1192/bjp.146.1.55CrossRef
27.
go back to reference Campbell A, Knowles S: A confirmatory factor analysis of the GHQ12 using a large Australian sample. Eur J Psychol Assess 2007, 23: 2–8. 10.1027/1015-5759.23.1.2CrossRef Campbell A, Knowles S: A confirmatory factor analysis of the GHQ12 using a large Australian sample. Eur J Psychol Assess 2007, 23: 2–8. 10.1027/1015-5759.23.1.2CrossRef
28.
go back to reference Rasch G: Probabilistic models for some intelligence & attainment tests. Chicago: University of Chicago Press; 1980. Rasch G: Probabilistic models for some intelligence & attainment tests. Chicago: University of Chicago Press; 1980.
29.
go back to reference Bond TG, Fox CM: Applying the Rasch model: Fundamental Measurement in the Human Sciences. London: Lawrence Erlbaum Associates; 2001. Bond TG, Fox CM: Applying the Rasch model: Fundamental Measurement in the Human Sciences. London: Lawrence Erlbaum Associates; 2001.
30.
go back to reference Smith EV: Detecting and evaluating the impact of multidimensionality using item fit statistics and principal component analysis of residuals. J Applied Measure 2002, 3: 205–231. Smith EV: Detecting and evaluating the impact of multidimensionality using item fit statistics and principal component analysis of residuals. J Applied Measure 2002, 3: 205–231.
31.
go back to reference Pallant JF, Miller RL, Tennant A: Evaluation of the Edinburgh Post Natal Depression Scale using Rasch analysis. BMC Psychiatry 2006, 6: 28. 10.1186/1471-244X-6-28PubMedCentralPubMedCrossRef Pallant JF, Miller RL, Tennant A: Evaluation of the Edinburgh Post Natal Depression Scale using Rasch analysis. BMC Psychiatry 2006, 6: 28. 10.1186/1471-244X-6-28PubMedCentralPubMedCrossRef
32.
go back to reference Smith AB, Wright EP, Rush R, Stark DP, Velikova G, Selby PJ: Rasch analysis of the dimensional structure of the Hospital Anxiety and Depression Scale. Psycho-oncol 2006, 15: 817–827. 10.1002/pon.1015CrossRef Smith AB, Wright EP, Rush R, Stark DP, Velikova G, Selby PJ: Rasch analysis of the dimensional structure of the Hospital Anxiety and Depression Scale. Psycho-oncol 2006, 15: 817–827. 10.1002/pon.1015CrossRef
33.
go back to reference Masters GN: A Rasch model for partial credit scoring. Psychometrika 1982, 47: 149–174. 10.1007/BF02296272CrossRef Masters GN: A Rasch model for partial credit scoring. Psychometrika 1982, 47: 149–174. 10.1007/BF02296272CrossRef
34.
go back to reference Linacre JM: A User's Guide to Winsteps/Ministeps Rasch Model Computer Programs. 2008. Linacre JM: A User's Guide to Winsteps/Ministeps Rasch Model Computer Programs. 2008.
35.
go back to reference Lai JS, Cella D, Chang CH, Bode RK, Heinemann AW: Item banking to improve shorten and computerize self-reported fatigue: an illustration of steps to create a core item bank from the FACIT-Fatigue Scale. Qual Life Res 2003, 12: 485–501. 10.1023/A:1025014509626PubMedCrossRef Lai JS, Cella D, Chang CH, Bode RK, Heinemann AW: Item banking to improve shorten and computerize self-reported fatigue: an illustration of steps to create a core item bank from the FACIT-Fatigue Scale. Qual Life Res 2003, 12: 485–501. 10.1023/A:1025014509626PubMedCrossRef
36.
go back to reference Bentler PM: Comparative fit indices in structural models. Psychol Bull 1990, 107: 238–246. 10.1037/0033-2909.107.2.238PubMedCrossRef Bentler PM: Comparative fit indices in structural models. Psychol Bull 1990, 107: 238–246. 10.1037/0033-2909.107.2.238PubMedCrossRef
37.
go back to reference Bollen KA: Structural equations with latent variables. New York: Wiley; 1989.CrossRef Bollen KA: Structural equations with latent variables. New York: Wiley; 1989.CrossRef
38.
go back to reference Steiger JH: Structural model evaluation and modification: An interval estimation approach. Multivariate Behavioural Research 1990, 25: 173–180. 10.1207/s15327906mbr2502_4CrossRef Steiger JH: Structural model evaluation and modification: An interval estimation approach. Multivariate Behavioural Research 1990, 25: 173–180. 10.1207/s15327906mbr2502_4CrossRef
39.
go back to reference Jöreskog K, Sörbom D: LISREL V: Analysis of linear structural relationships by the method of maximum likelihood. Chicago: National Educational Resources; 1981. Jöreskog K, Sörbom D: LISREL V: Analysis of linear structural relationships by the method of maximum likelihood. Chicago: National Educational Resources; 1981.
40.
go back to reference Browne MW, Cudeck R: Single sample cross-validation indices for covariation structures. Multivariate Behavioral Research 1989, 24: 445–455. 10.1207/s15327906mbr2404_4CrossRef Browne MW, Cudeck R: Single sample cross-validation indices for covariation structures. Multivariate Behavioral Research 1989, 24: 445–455. 10.1207/s15327906mbr2404_4CrossRef
41.
go back to reference Tanaka JS: "How big is big enough?": Sample size and goodness of fit in structural equation models with latent variables. Child Development 1987, 58: 134–146. 10.2307/1130296CrossRef Tanaka JS: "How big is big enough?": Sample size and goodness of fit in structural equation models with latent variables. Child Development 1987, 58: 134–146. 10.2307/1130296CrossRef
Metadata
Title
A Rasch and confirmatory factor analysis of the General Health Questionnaire (GHQ) - 12
Authors
Adam B Smith
Lesley J Fallowfield
Dan P Stark
Galina Velikova
Valerie Jenkins
Publication date
01-12-2010
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2010
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/1477-7525-8-45

Other articles of this Issue 1/2010

Health and Quality of Life Outcomes 1/2010 Go to the issue