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Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2006

Open Access 01-12-2006 | Research

Synchrony of change in depressive symptoms, health status, and quality of life in persons with clinical depression

Authors: Paula H Diehr, Ann M Derleth, Stephen P McKenna, Mona L Martin, Donald M Bushnell, Gregory Simon, Donald L Patrick

Published in: Health and Quality of Life Outcomes | Issue 1/2006

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Abstract

Background

Little is known about longitudinal associations among measures of depression, mental and physical health, and quality of life (QOL). We followed 982 clinically depressed persons to determine which measures changed and whether the change was synchronous with change in depressive symptoms.

Methods

Data were from the Longitudinal Investigation of Depression Outcomes (LIDO). Depressive symptoms, physical and mental health, and quality of life were measured at baseline, 6 weeks, 3 months, and 9 months. Change in the measures was examined over time and for persons with different levels of change in depressive symptoms.

Results

On average, all of the measures improved significantly over time, and most were synchronous with change in depressive symptoms. Measures of mental health changed the most, and physical health the least. The measures of change in QOL were intermediate. The 6-week change in QOL could be explained completely by change in depressive symptoms. The instruments varied in sensitivity to changes in depressive symptoms.

Conclusion

In clinically depressed persons, measures of physical health, mental health, and quality of life showed consistent longitudinal associations with measures of depressive symptoms.
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Metadata
Title
Synchrony of change in depressive symptoms, health status, and quality of life in persons with clinical depression
Authors
Paula H Diehr
Ann M Derleth
Stephen P McKenna
Mona L Martin
Donald M Bushnell
Gregory Simon
Donald L Patrick
Publication date
01-12-2006
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2006
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/1477-7525-4-27

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