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Health and Quality of Life Outcomes

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Open Access 01-12-2012 | Research

Psychometric properties of the disease-specific health-related quality of life instrument VascuQoL in a Swedish setting

Authors: Joakim Nordanstig, Jan Karlsson, Monica Pettersson, Christine Wann-Hansson

Published in: Health and Quality of Life Outcomes | Issue 1/2012

Abstract

Background

Traditional outcome measures in peripheral arterial disease (PAD) provide insufficient information regarding patient benefit. It has therefore been suggested to add patient-reported outcome measures. The main aim of this study was to validate the Swedish Vascular Quality of Life questionnaire (VascuQoL) version, a patient-reported PAD-specific health-related quality of life (HRQoL) instrument.

Methods

Two-hundred PAD patients were consecutively recruited from two university hospitals. Out of the 200 subjects, 129 had intermittent claudication and 71 had critical limb ischemia. Mean age was 70 ± 9 y and 57% of the participants were male. All patients completed SF-36 and VascuQoL at the vascular outpatient clinic, when evaluated for invasive treatment. Risk factors and physiological parameters were registered. Construct validity was tested by correlation analysis versus SF-36 and was also assessed with multitrait/multi-item scaling analysis (MTMI). Sensitivity analysis regarding disease severity identification was performed. Reliability was assessed with Cronbach's alpha and responsiveness by standardized response mean (SRM) calculations.

Results

Significant correlations were demonstrated between relevant subscales of VascuQoL and SF-36. MTMI showed acceptable construct validity, but some scaling-errors. VascuQoL significantly (p < 0.001) discriminated claudicants from critical limb ischemia patients. Cronbach's alpha was 0.94 and SRM 1.02 (sum score).

Conclusions

The Swedish version of VascuQoL is valid and quantifies central aspects of HRQoL in PAD patients. Sensitivity analysis showed high ability to differentiate between disease severity and SRM illustrated excellent responsiveness. The relative abundance of items however makes use in the everyday clinical setting somewhat difficult.

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Title: Psychometric properties of the disease-specific health-related quality of life instrument VascuQoL in a Swedish setting
Authors: Joakim Nordanstig
Jan Karlsson
Monica Pettersson
Christine Wann-Hansson
Publication date: 01-12-2012
Publisher: BioMed Central
Published in: Health and Quality of Life Outcomes / Issue 1/2012
Electronic ISSN: 1477-7525
DOI: https://doi.org/10.1186/1477-7525-10-45

ACC 2024 Congress

Springer Medicine

Psychometric properties of the disease-specific health-related quality of life instrument VascuQoL in a Swedish setting

Abstract

Background

Methods

Results

Conclusions

ACC 2024 Congress

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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