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Published in: BMC Health Services Research 1/2011

Open Access 01-12-2011 | Research article

Healthcare costs in patients with metastatic lung cancer receiving chemotherapy

Authors: Montserrat Vera-Llonch, Derek Weycker, Andrew Glass, Sue Gao, Rohit Borker, Beth Barber, Gerry Oster

Published in: BMC Health Services Research | Issue 1/2011

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Abstract

Background

To characterize healthcare resource utilization and costs in patients with metastatic lung cancer receiving chemotherapy in the US.

Methods

Using data from a large private multi-payer health insurance claims database (2000-2006), we identified all patients beginning chemotherapy for metastatic lung cancer. Healthcare resource use (inpatient, outpatient, medications) and costs were tallied over time from date of therapy initiation ("index date") to date of disenrollment from the health plan (in most instances, presumably due to death) or the end of the study period, whichever occurred first. Healthcare utilization and costs were characterized using Kaplan-Meier sample average methods.

Results

The study population consisted of 4068 patients; mean (SD) age was 65 (11) years. Over a median follow-up of 334 days, study subjects averaged 1.5 hospital admissions, 8.9 total inpatient days, and 69 physician office and hospital outpatient visits. Mean (95% CI) cumulative total healthcare costs were $125,849 ($120,228, $131,231). Costs of outpatient medical services and inpatient care constituted 34% and 20% of total healthcare costs, respectively; corresponding estimates for outpatient chemotherapy and other medication were 22% and 24%.

Conclusion

Our study sheds additional light on the burden of metastatic lung cancer among patients receiving chemotherapy, in terms of total cost thru end of life as well as component costs by setting and type of service, and may be useful in informing medical resource allocation in this patient population.
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Literature
1.
go back to reference American Cancer Society: Cancer Facts & Figures 2009. 2009, Atlanta: American Cancer Society American Cancer Society: Cancer Facts & Figures 2009. 2009, Atlanta: American Cancer Society
2.
go back to reference Ries LAG, Harkins D, Krapcho M, et al: SEER Cancer Statistics Review, 1975-2003. 2006, Bethesda, MD, National Cancer Institute Ries LAG, Harkins D, Krapcho M, et al: SEER Cancer Statistics Review, 1975-2003. 2006, Bethesda, MD, National Cancer Institute
4.
go back to reference Yabroff KR, Lamont EB, Mariotto A, Warren JL, Topor M, Meekins A, Brown ML: Cost of care for elderly cancer patients in the United States. J Natl Cancer Inst. 2008, 100: 630-41. 10.1093/jnci/djn103.CrossRefPubMed Yabroff KR, Lamont EB, Mariotto A, Warren JL, Topor M, Meekins A, Brown ML: Cost of care for elderly cancer patients in the United States. J Natl Cancer Inst. 2008, 100: 630-41. 10.1093/jnci/djn103.CrossRefPubMed
5.
go back to reference National Comprehensive Cancer Network (NCCN): clinical practice guidelines in oncology (NCCN v1. 2010). (last accessed June 16, 2010), [http://www.nccn.org] National Comprehensive Cancer Network (NCCN): clinical practice guidelines in oncology (NCCN v1. 2010). (last accessed June 16, 2010), [http://​www.​nccn.​org]
6.
go back to reference Karnon J, Kerr GR, Jack W, Papo NL, Cameron DA: Health care costs for the treatment of breast cancer recurrent events: estimates from a UK-based patient-level analysis. Br J Cancer. 2007, 97: 479-85. 10.1038/sj.bjc.6603887.CrossRefPubMedPubMedCentral Karnon J, Kerr GR, Jack W, Papo NL, Cameron DA: Health care costs for the treatment of breast cancer recurrent events: estimates from a UK-based patient-level analysis. Br J Cancer. 2007, 97: 479-85. 10.1038/sj.bjc.6603887.CrossRefPubMedPubMedCentral
7.
go back to reference Lang K, Marciniak MD, Faries D, Stokes M, Buesching D, Earle C, Treat J, Babineaux S, Morissette N, Thompson D: Costs of first-line doublet chemotherapy and lifetime medical care in advanced non-small-cell lung cancer in the United States. Value Health. 2009, 12 (4): 481-8. 10.1111/j.1524-4733.2008.00472.x.CrossRefPubMed Lang K, Marciniak MD, Faries D, Stokes M, Buesching D, Earle C, Treat J, Babineaux S, Morissette N, Thompson D: Costs of first-line doublet chemotherapy and lifetime medical care in advanced non-small-cell lung cancer in the United States. Value Health. 2009, 12 (4): 481-8. 10.1111/j.1524-4733.2008.00472.x.CrossRefPubMed
8.
go back to reference Fox KM, Brooks JM, Kim J: Metastatic Non-small cell lung cancer: Costs associated with disease progression. Am J Manag Care. 2008, 14 (9): 565-71.PubMed Fox KM, Brooks JM, Kim J: Metastatic Non-small cell lung cancer: Costs associated with disease progression. Am J Manag Care. 2008, 14 (9): 565-71.PubMed
9.
go back to reference Woodward RM, Brown ML, Stewart ST, Cronin KA, Cutler DM: The value of medical interventions for lung cancer in the elderly: Results from SEER-CMHSF. Cancer. 2007, 110: 2511-8. 10.1002/cncr.23058.CrossRefPubMed Woodward RM, Brown ML, Stewart ST, Cronin KA, Cutler DM: The value of medical interventions for lung cancer in the elderly: Results from SEER-CMHSF. Cancer. 2007, 110: 2511-8. 10.1002/cncr.23058.CrossRefPubMed
10.
go back to reference Au DH, Udris EM, Fihn SD, McDonell MB, Curtis R: Differences in health care utilization at the end of life among patients with chronic obstructive pulmonary disease and patients with lung cancer. Arch Intern Med. 2006, 166: 326-311. 10.1001/archinte.166.3.326.CrossRefPubMed Au DH, Udris EM, Fihn SD, McDonell MB, Curtis R: Differences in health care utilization at the end of life among patients with chronic obstructive pulmonary disease and patients with lung cancer. Arch Intern Med. 2006, 166: 326-311. 10.1001/archinte.166.3.326.CrossRefPubMed
11.
go back to reference Kutikova L, Bowman L, Chang S, Long SR, Obasaju C, Crown WH: The economic burden of lung cancer and the associated costs of treatment failure in the United States. Lung Cancer. 2005, 50: 143-54. 10.1016/j.lungcan.2005.06.005.CrossRefPubMed Kutikova L, Bowman L, Chang S, Long SR, Obasaju C, Crown WH: The economic burden of lung cancer and the associated costs of treatment failure in the United States. Lung Cancer. 2005, 50: 143-54. 10.1016/j.lungcan.2005.06.005.CrossRefPubMed
12.
go back to reference Lin DY, Feuer EJ, Etzioni R, Wax Y: Estimating medical costs from incomplete follow-up data. Biometrics. 1997, 53: 419-434. 10.2307/2533947.CrossRefPubMed Lin DY, Feuer EJ, Etzioni R, Wax Y: Estimating medical costs from incomplete follow-up data. Biometrics. 1997, 53: 419-434. 10.2307/2533947.CrossRefPubMed
13.
go back to reference Efron B: Bootstrap Methods: Another look at the jackknife. The Annals of Statistics. 1979, 7 (1): 1-26. 10.1214/aos/1176344552.CrossRef Efron B: Bootstrap Methods: Another look at the jackknife. The Annals of Statistics. 1979, 7 (1): 1-26. 10.1214/aos/1176344552.CrossRef
14.
go back to reference Cooper GS, Yuan Z, Stange KC, Amini SB, Dennis LK, Rimm AA: The utility of Medicare claims for measuring cancer stage. Medical Care. 1999, 37 (7): 706-711. 10.1097/00005650-199907000-00010.CrossRefPubMed Cooper GS, Yuan Z, Stange KC, Amini SB, Dennis LK, Rimm AA: The utility of Medicare claims for measuring cancer stage. Medical Care. 1999, 37 (7): 706-711. 10.1097/00005650-199907000-00010.CrossRefPubMed
Metadata
Title
Healthcare costs in patients with metastatic lung cancer receiving chemotherapy
Authors
Montserrat Vera-Llonch
Derek Weycker
Andrew Glass
Sue Gao
Rohit Borker
Beth Barber
Gerry Oster
Publication date
01-12-2011
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2011
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/1472-6963-11-305

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