Skip to main content
Top
Published in: BMC Health Services Research 1/2011

Open Access 01-12-2011 | Research article

High incidence of medication documentation errors in a Swiss university hospital due to the handwritten prescription process

Authors: Maximilian J Hartel, Lukas P Staub, Christoph Röder, Stefan Eggli

Published in: BMC Health Services Research | Issue 1/2011

Login to get access

Abstract

Background

Medication errors have been reported to be a leading cause of death in hospitalized patients. In this study we focused on identifying and quantifying errors in the handwritten drug ordering and dispensing documentation processes which could possibly lead to adverse drug events.

Methods

We studied 1,934 ordered agents (165 consecutive patients) retrospectively for medication documentation errors. Errors were categorized into: Prescribing errors, transcription errors and administration documentation errors on the nurses' medication lists. The legibility of prescriptions was analyzed to explore its possible influence on the error rate in the documentation process.

Results

Documentation errors occurred in 65 of 1,934 prescribed agents (3.5%). The incidence of patient charts showing at least one error was 43%. Prescribing errors were found 39 times (37%), transcription errors 56 times (53%), and administration documentation errors 10 times (10%). The handwriting readability was rated as good in 2%, moderate in 42%, bad in 52%, and unreadable in 4%.

Conclusions

This study revealed a high incidence of documentation errors in the traditional handwritten prescription process. Most errors occurred when prescriptions were transcribed into the patients' chart. The readability of the handwritten prescriptions was generally bad. Replacing the traditional handwritten documentation process with information technology could potentially improve the safety in the medication process.
Appendix
Available only for authorised users
Literature
1.
go back to reference Kohn LT, Corrigan JM, Donaldson MS: To Err Is Human: Building a Safer Health System. 1999, Washington, D.C.: National Academies Press Kohn LT, Corrigan JM, Donaldson MS: To Err Is Human: Building a Safer Health System. 1999, Washington, D.C.: National Academies Press
2.
go back to reference Bobb A, Gleason K, Husch M, Feinglass J, Yarnold PR, Noskin GA: The epidemiology of prescribing errors: the potential impact of computerized prescriber order entry. Arch Intern Med. 2004, 164 (7): 785-792. 10.1001/archinte.164.7.785.CrossRefPubMed Bobb A, Gleason K, Husch M, Feinglass J, Yarnold PR, Noskin GA: The epidemiology of prescribing errors: the potential impact of computerized prescriber order entry. Arch Intern Med. 2004, 164 (7): 785-792. 10.1001/archinte.164.7.785.CrossRefPubMed
3.
go back to reference Brennan TA, Leape LL, Laird NM, Hebert L, Localio AR, Lawthers AG, Newhouse JP, Weiler PC, Hiatt HH: Incidence of adverse events and negligence in hospitalized patients. Results of the Harvard Medical Practice Study I. N Engl J Med. 1991, 324 (6): 370-376. 10.1056/NEJM199102073240604.CrossRefPubMed Brennan TA, Leape LL, Laird NM, Hebert L, Localio AR, Lawthers AG, Newhouse JP, Weiler PC, Hiatt HH: Incidence of adverse events and negligence in hospitalized patients. Results of the Harvard Medical Practice Study I. N Engl J Med. 1991, 324 (6): 370-376. 10.1056/NEJM199102073240604.CrossRefPubMed
4.
go back to reference Leape LL, Brennan TA, Laird N, Lawthers AG, Localio AR, Barnes BA, Hebert L, Newhouse JP, Weiler PC, Hiatt H: The nature of adverse events in hospitalized patients. Results of the Harvard Medical Practice Study II. N Engl J Med. 1991, 324 (6): 377-384. 10.1056/NEJM199102073240605.CrossRefPubMed Leape LL, Brennan TA, Laird N, Lawthers AG, Localio AR, Barnes BA, Hebert L, Newhouse JP, Weiler PC, Hiatt H: The nature of adverse events in hospitalized patients. Results of the Harvard Medical Practice Study II. N Engl J Med. 1991, 324 (6): 377-384. 10.1056/NEJM199102073240605.CrossRefPubMed
5.
go back to reference Kopp BJ, Erstad BL, Allen ME, Theodorou AA, Priestley G: Medication errors and adverse drug events in an intensive care unit: direct observation approach for detection. Crit Care Med. 2006, 34 (2): 415-425. 10.1097/01.CCM.0000198106.54306.D7.CrossRefPubMed Kopp BJ, Erstad BL, Allen ME, Theodorou AA, Priestley G: Medication errors and adverse drug events in an intensive care unit: direct observation approach for detection. Crit Care Med. 2006, 34 (2): 415-425. 10.1097/01.CCM.0000198106.54306.D7.CrossRefPubMed
6.
go back to reference Dormann H, Neubert A, Criegee-Rieck M, Egger T, Radespiel-Troger M, Azaz-Livshits T, Levy M, Brune K, Hahn EG: Readmissions and adverse drug reactions in internal medicine: the economic impact. J Intern Med. 2004, 255 (6): 653-663. 10.1111/j.1365-2796.2004.01326.x.CrossRefPubMed Dormann H, Neubert A, Criegee-Rieck M, Egger T, Radespiel-Troger M, Azaz-Livshits T, Levy M, Brune K, Hahn EG: Readmissions and adverse drug reactions in internal medicine: the economic impact. J Intern Med. 2004, 255 (6): 653-663. 10.1111/j.1365-2796.2004.01326.x.CrossRefPubMed
7.
go back to reference Buajordet I, Ebbesen J, Erikssen J, Brors O, Hilberg T: Fatal adverse drug events: the paradox of drug treatment. J Intern Med. 2001, 250 (4): 327-341. 10.1046/j.1365-2796.2001.00892.x.CrossRefPubMed Buajordet I, Ebbesen J, Erikssen J, Brors O, Hilberg T: Fatal adverse drug events: the paradox of drug treatment. J Intern Med. 2001, 250 (4): 327-341. 10.1046/j.1365-2796.2001.00892.x.CrossRefPubMed
8.
go back to reference Barker KN, Flynn EA, Pepper GA, Bates DW, Mikeal RL: Medication errors observed in 36 health care facilities. Arch Intern Med. 2002, 162 (16): 1897-1903. 10.1001/archinte.162.16.1897.CrossRefPubMed Barker KN, Flynn EA, Pepper GA, Bates DW, Mikeal RL: Medication errors observed in 36 health care facilities. Arch Intern Med. 2002, 162 (16): 1897-1903. 10.1001/archinte.162.16.1897.CrossRefPubMed
9.
go back to reference Ash JS, Gorman PN, Seshadri V, Hersh WR: Computerized physician order entry in U.S. hospitals: results of a 2002 survey. J Am Med Inform Assoc. 2004, 11 (2): 95-99.CrossRefPubMedPubMedCentral Ash JS, Gorman PN, Seshadri V, Hersh WR: Computerized physician order entry in U.S. hospitals: results of a 2002 survey. J Am Med Inform Assoc. 2004, 11 (2): 95-99.CrossRefPubMedPubMedCentral
10.
go back to reference Koppel R, Metlay JP, Cohen A, Abaluck B, Localio AR, Kimmel SE, Strom BL: Role of computerized physician order entry systems in facilitating medication errors. Jama. 2005, 293 (10): 1197-1203. 10.1001/jama.293.10.1197.CrossRefPubMed Koppel R, Metlay JP, Cohen A, Abaluck B, Localio AR, Kimmel SE, Strom BL: Role of computerized physician order entry systems in facilitating medication errors. Jama. 2005, 293 (10): 1197-1203. 10.1001/jama.293.10.1197.CrossRefPubMed
11.
go back to reference Leape LL, Bates DW, Cullen DJ, Cooper J, Demonaco HJ, Gallivan T, Hallisey R, Ives J, Laird N, Laffel G, Nemeskal R, Petersen LA, Porter K, Servi D, Shea B, Small SD, Sweitzer BJ, Taylor Thompson B, Vander Vliet M, Group APS, Leape L, Servi D, Laird N, Bates DW, Hojonski-Diaz P, Petersen LA, Petrycki S, Vander Vliet M, Cotugno M, Patterson H, et al: Systems analysis of adverse drug events. ADE Prevention Study Group. Jama. 1995, 274 (1): 35-43. 10.1001/jama.274.1.35.CrossRefPubMed Leape LL, Bates DW, Cullen DJ, Cooper J, Demonaco HJ, Gallivan T, Hallisey R, Ives J, Laird N, Laffel G, Nemeskal R, Petersen LA, Porter K, Servi D, Shea B, Small SD, Sweitzer BJ, Taylor Thompson B, Vander Vliet M, Group APS, Leape L, Servi D, Laird N, Bates DW, Hojonski-Diaz P, Petersen LA, Petrycki S, Vander Vliet M, Cotugno M, Patterson H, et al: Systems analysis of adverse drug events. ADE Prevention Study Group. Jama. 1995, 274 (1): 35-43. 10.1001/jama.274.1.35.CrossRefPubMed
12.
13.
go back to reference Grandt D, Friebel H, Müller-Oerlinghausen B: Arzneitherapie(un)sicherheit: Notwendige Schritte zur Verbesserung der Patientensicherheit bei medikamentöser Therapie. Deutsches Ärzteblatt. 2005, 102 (8). Grandt D, Friebel H, Müller-Oerlinghausen B: Arzneitherapie(un)sicherheit: Notwendige Schritte zur Verbesserung der Patientensicherheit bei medikamentöser Therapie. Deutsches Ärzteblatt. 2005, 102 (8).
14.
go back to reference Davidoff F, Batalden P, Stevens D, Ogrinc G, Mooney S: Publication guidelines for quality improvement in health care: evolution of the SQUIRE project. Qual Saf Health Care. 2008, 17 (Suppl 1): i3-9. 10.1136/qshc.2008.029066.CrossRefPubMedPubMedCentral Davidoff F, Batalden P, Stevens D, Ogrinc G, Mooney S: Publication guidelines for quality improvement in health care: evolution of the SQUIRE project. Qual Saf Health Care. 2008, 17 (Suppl 1): i3-9. 10.1136/qshc.2008.029066.CrossRefPubMedPubMedCentral
15.
go back to reference Ogrinc G, Mooney SE, Estrada C, Foster T, Goldmann D, Hall LW, Huizinga MM, Liu SK, Mills P, Neily J, Nelson W, Pronovost PJ, Provost L, Rubenstein LV, Speroff T, Splaine M, Thomson R, Tomolo AM, Watts B: The SQUIRE (Standards for QUality Improvement Reporting Excellence) guidelines for quality improvement reporting: explanation and elaboration. Qual Saf Health Care. 2008, 17 (Suppl 1): i13-32. 10.1136/qshc.2008.029058.CrossRefPubMedPubMedCentral Ogrinc G, Mooney SE, Estrada C, Foster T, Goldmann D, Hall LW, Huizinga MM, Liu SK, Mills P, Neily J, Nelson W, Pronovost PJ, Provost L, Rubenstein LV, Speroff T, Splaine M, Thomson R, Tomolo AM, Watts B: The SQUIRE (Standards for QUality Improvement Reporting Excellence) guidelines for quality improvement reporting: explanation and elaboration. Qual Saf Health Care. 2008, 17 (Suppl 1): i13-32. 10.1136/qshc.2008.029058.CrossRefPubMedPubMedCentral
16.
go back to reference Bates DW, Boyle DL, Vander Vliet MB, Schneider J, Leape L: Relationship between medication errors and adverse drug events. J Gen Intern Med. 1995, 10 (4): 199-205. 10.1007/BF02600255.CrossRefPubMed Bates DW, Boyle DL, Vander Vliet MB, Schneider J, Leape L: Relationship between medication errors and adverse drug events. J Gen Intern Med. 1995, 10 (4): 199-205. 10.1007/BF02600255.CrossRefPubMed
17.
go back to reference Gurwitz JH, Field TS, Judge J, Rochon P, Harrold LR, Cadoret C, Lee M, White K, LaPrino J, Erramuspe-Mainard J, DeFlorio M, Gavendo L, Auger J, Bates DW: The incidence of adverse drug events in two large academic long-term care facilities. Am J Med. 2005, 118 (3): 251-258. 10.1016/j.amjmed.2004.09.018.CrossRefPubMed Gurwitz JH, Field TS, Judge J, Rochon P, Harrold LR, Cadoret C, Lee M, White K, LaPrino J, Erramuspe-Mainard J, DeFlorio M, Gavendo L, Auger J, Bates DW: The incidence of adverse drug events in two large academic long-term care facilities. Am J Med. 2005, 118 (3): 251-258. 10.1016/j.amjmed.2004.09.018.CrossRefPubMed
18.
go back to reference Brennan TA, Hebert LE, Laird NM, Lawthers A, Thorpe KE, Leape LL, Localio AR, Lipsitz SR, Newhouse JP, Weiler PC, Hiatt H: Hospital characteristics associated with adverse events and substandard care. Jama. 1991, 265 (24): 3265-3269. 10.1001/jama.265.24.3265.CrossRefPubMed Brennan TA, Hebert LE, Laird NM, Lawthers A, Thorpe KE, Leape LL, Localio AR, Lipsitz SR, Newhouse JP, Weiler PC, Hiatt H: Hospital characteristics associated with adverse events and substandard care. Jama. 1991, 265 (24): 3265-3269. 10.1001/jama.265.24.3265.CrossRefPubMed
19.
go back to reference Winslow EH, Nestor VA, Davidoff SK, Thompson PG, Borum JC: Legibility and completeness of physicians' handwritten medication orders. Heart Lung. 1997, 26 (2): 158-164. 10.1016/S0147-9563(97)90076-5.CrossRefPubMed Winslow EH, Nestor VA, Davidoff SK, Thompson PG, Borum JC: Legibility and completeness of physicians' handwritten medication orders. Heart Lung. 1997, 26 (2): 158-164. 10.1016/S0147-9563(97)90076-5.CrossRefPubMed
20.
go back to reference Alyamani NA, Hopf Y, Williams DJ: Prescription quality in an acute medical ward. Pharmacoepidemiol Drug Saf. 2009, 18 (12): 1158-1165. 10.1002/pds.1830.CrossRefPubMed Alyamani NA, Hopf Y, Williams DJ: Prescription quality in an acute medical ward. Pharmacoepidemiol Drug Saf. 2009, 18 (12): 1158-1165. 10.1002/pds.1830.CrossRefPubMed
21.
go back to reference Bates DW, Leape LL, Cullen DJ, Laird N, Petersen LA, Teich JM, Burdick E, Hickey M, Kleefield S, Shea B, Vander Vliet M, Seger DL: Effect of computerized physician order entry and a team intervention on prevention of serious medication errors. Jama. 1998, 280 (15): 1311-1316. 10.1001/jama.280.15.1311.CrossRefPubMed Bates DW, Leape LL, Cullen DJ, Laird N, Petersen LA, Teich JM, Burdick E, Hickey M, Kleefield S, Shea B, Vander Vliet M, Seger DL: Effect of computerized physician order entry and a team intervention on prevention of serious medication errors. Jama. 1998, 280 (15): 1311-1316. 10.1001/jama.280.15.1311.CrossRefPubMed
22.
go back to reference Kuperman GJ, Gibson RF: Computer physician order entry: benefits, costs, and issues. Ann Intern Med. 2003, 139 (1): 31-39.CrossRefPubMed Kuperman GJ, Gibson RF: Computer physician order entry: benefits, costs, and issues. Ann Intern Med. 2003, 139 (1): 31-39.CrossRefPubMed
23.
go back to reference Bates DW, Teich JM, Lee J, Seger D, Kuperman GJ, Ma'Luf N, Boyle D, Leape L: The impact of computerized physician order entry on medication error prevention. J Am Med Inform Assoc. 1999, 6 (4): 313-321. 10.1136/jamia.1999.00660313.CrossRefPubMedPubMedCentral Bates DW, Teich JM, Lee J, Seger D, Kuperman GJ, Ma'Luf N, Boyle D, Leape L: The impact of computerized physician order entry on medication error prevention. J Am Med Inform Assoc. 1999, 6 (4): 313-321. 10.1136/jamia.1999.00660313.CrossRefPubMedPubMedCentral
24.
go back to reference Burt CW, Hing E: Use of computerized clinical support systems in medical settings: United States, 2001-03. Adv Data. 2005, 1-8. 353 Burt CW, Hing E: Use of computerized clinical support systems in medical settings: United States, 2001-03. Adv Data. 2005, 1-8. 353
25.
go back to reference Nightingale PG, Adu D, Richards NT, Peters M: Implementation of rules based computerised bedside prescribing and administration: intervention study. Bmj. 2000, 320 (7237): 750-753. 10.1136/bmj.320.7237.750.CrossRefPubMedPubMedCentral Nightingale PG, Adu D, Richards NT, Peters M: Implementation of rules based computerised bedside prescribing and administration: intervention study. Bmj. 2000, 320 (7237): 750-753. 10.1136/bmj.320.7237.750.CrossRefPubMedPubMedCentral
26.
go back to reference Upperman JS, Staley P, Friend K, Neches W, Kazimer D, Benes J, Wiener ES: The impact of hospitalwide computerized physician order entry on medical errors in a pediatric hospital. J Pediatr Surg. 2005, 40 (1): 57-59. 10.1016/j.jpedsurg.2004.09.024.CrossRefPubMed Upperman JS, Staley P, Friend K, Neches W, Kazimer D, Benes J, Wiener ES: The impact of hospitalwide computerized physician order entry on medical errors in a pediatric hospital. J Pediatr Surg. 2005, 40 (1): 57-59. 10.1016/j.jpedsurg.2004.09.024.CrossRefPubMed
Metadata
Title
High incidence of medication documentation errors in a Swiss university hospital due to the handwritten prescription process
Authors
Maximilian J Hartel
Lukas P Staub
Christoph Röder
Stefan Eggli
Publication date
01-12-2011
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2011
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/1472-6963-11-199

Other articles of this Issue 1/2011

BMC Health Services Research 1/2011 Go to the issue