Skip to main content
Top
Published in: BMC Health Services Research 1/2010

Open Access 01-12-2010 | Research article

Cost-effectiveness of HIV prevention interventions in Andhra Pradesh state of India

Authors: Lalit Dandona, SG Prem Kumar, G Anil Kumar, Rakhi Dandona

Published in: BMC Health Services Research | Issue 1/2010

Login to get access

Abstract

Background

Information on cost-effectiveness of the range of HIV prevention interventions is a useful contributor to decisions on the best use of resources to prevent HIV. We conducted this assessment for the state of Andhra Pradesh that has the highest HIV burden in India.

Methods

Based on data from a representative sample of 128 public-funded HIV prevention programs of 14 types in Andhra Pradesh, we have recently reported the number of HIV infections averted by each type of HIV prevention intervention and their cost. Using estimates of the age of onset of HIV infection, we used standard methods to calculate the cost per Disability Adjusted Life Year (DALY) saved as a measure of cost-effectiveness of each type of HIV prevention intervention.

Results

The point estimates of the cost per DALY saved were less than US $50 for blood banks, men who have sex with men programmes, voluntary counselling and testing centres, prevention of parent to child transmission clinics, sexually transmitted infection clinics, and women sex worker programmes; between US $50 and 100 for truckers and migrant labourer programmes; more than US $100 and up to US $410 for composite, street children, condom promotion, prisoners and workplace programmes and mass media campaign for the general public. The uncertainty range around these estimates was very wide for several interventions, with the ratio of the high to the low estimates infinite for five interventions.

Conclusions

The point estimates for the cost per DALY saved from the averted HIV infections for all interventions was much lower than the per capita gross domestic product in this Indian state. While these indicative cost-effectiveness estimates can inform HIV control planning currently, the wide uncertainty range around estimates for several interventions suggest the need for more firm data for estimating cost-effectiveness of HIV prevention interventions in India.
Appendix
Available only for authorised users
Literature
1.
go back to reference National AIDS Control Organisation, Ministry of Health & Family Welfare, Government of India: National AIDS control programme, phase III. New Delhi. 2006 National AIDS Control Organisation, Ministry of Health & Family Welfare, Government of India: National AIDS control programme, phase III. New Delhi. 2006
4.
go back to reference Dandona L, Kumar SG, Kumar GA, Dandona R: Economic analysis of HIV prevention interventions in Andhra Pradesh state of India to inform resource allocation. AIDS. 2009, 23 (2): 233-242. 10.1097/QAD.0b013e328320accc.CrossRefPubMed Dandona L, Kumar SG, Kumar GA, Dandona R: Economic analysis of HIV prevention interventions in Andhra Pradesh state of India to inform resource allocation. AIDS. 2009, 23 (2): 233-242. 10.1097/QAD.0b013e328320accc.CrossRefPubMed
5.
go back to reference Dandona L, Sisodia P, Kumar SG, Ramesh YK, Kumar AA, Rao MC, Marseille E, Someshwar M, Marshall N, Kahn JG: HIV prevention programmes for female sex workers in Andhra Pradesh, India: outputs, cost and efficiency. BMC Public Health. 2005, 5 (98): 98-10.1186/1471-2458-5-98.CrossRefPubMedPubMedCentral Dandona L, Sisodia P, Kumar SG, Ramesh YK, Kumar AA, Rao MC, Marseille E, Someshwar M, Marshall N, Kahn JG: HIV prevention programmes for female sex workers in Andhra Pradesh, India: outputs, cost and efficiency. BMC Public Health. 2005, 5 (98): 98-10.1186/1471-2458-5-98.CrossRefPubMedPubMedCentral
6.
go back to reference Dandona L, Sisodia P, Ramesh YK, Kumar SG, Kumar AA, Rao MC, Someshwar M, Hansl B, Marshall N, Marseille E, et al: Cost and efficiency of HIV voluntary counselling and testing centres in Andhra Pradesh, India. Natl Med J India. 2005, 18 (1): 26-31.PubMed Dandona L, Sisodia P, Ramesh YK, Kumar SG, Kumar AA, Rao MC, Someshwar M, Hansl B, Marshall N, Marseille E, et al: Cost and efficiency of HIV voluntary counselling and testing centres in Andhra Pradesh, India. Natl Med J India. 2005, 18 (1): 26-31.PubMed
7.
go back to reference Dandona L, Sisodia P, Prasad TL, Marseille E, Chalapathi Rao M, Kumar AA, Kumar SG, Ramesh YK, Over M, Someshwar M, et al: Cost and efficiency of public sector sexually transmitted infection clinics in Andhra Pradesh, India. BMC Health Serv Res. 2005, 5 (69): 69-10.1186/1472-6963-5-69.CrossRefPubMedPubMedCentral Dandona L, Sisodia P, Prasad TL, Marseille E, Chalapathi Rao M, Kumar AA, Kumar SG, Ramesh YK, Over M, Someshwar M, et al: Cost and efficiency of public sector sexually transmitted infection clinics in Andhra Pradesh, India. BMC Health Serv Res. 2005, 5 (69): 69-10.1186/1472-6963-5-69.CrossRefPubMedPubMedCentral
8.
go back to reference Dandona L, Kumar SG, Ramesh YK, Rao MC, Marseille E, Kahn JG, Dandona R: Outputs, cost and efficiency of public sector centres for prevention of mother to child transmission of HIV in Andhra Pradesh, India. BMC Health Serv Res. 2008, 8 (26): 26-10.1186/1472-6963-8-26.CrossRefPubMedPubMedCentral Dandona L, Kumar SG, Ramesh YK, Rao MC, Marseille E, Kahn JG, Dandona R: Outputs, cost and efficiency of public sector centres for prevention of mother to child transmission of HIV in Andhra Pradesh, India. BMC Health Serv Res. 2008, 8 (26): 26-10.1186/1472-6963-8-26.CrossRefPubMedPubMedCentral
9.
go back to reference Dandona L, Kumar SP, Ramesh Y, Rao MC, Kumar AA, Marseille E, Kahn JG, Dandona R: Changing cost of HIV interventions in the context of scaling-up in India. AIDS. 2008, 22 (Suppl 1 (1)): S43-49. 10.1097/01.aids.0000327622.24232.aa.CrossRefPubMedPubMedCentral Dandona L, Kumar SP, Ramesh Y, Rao MC, Kumar AA, Marseille E, Kahn JG, Dandona R: Changing cost of HIV interventions in the context of scaling-up in India. AIDS. 2008, 22 (Suppl 1 (1)): S43-49. 10.1097/01.aids.0000327622.24232.aa.CrossRefPubMedPubMedCentral
10.
go back to reference Kumar SG, Dandona R, Schneider JA, Ramesh YK, Dandona L: Outputs and cost of HIV prevention programmes for truck drivers in Andhra Pradesh, India. BMC Health Serv Res. 2009, 9 (82): 82-10.1186/1472-6963-9-82.CrossRefPubMedPubMedCentral Kumar SG, Dandona R, Schneider JA, Ramesh YK, Dandona L: Outputs and cost of HIV prevention programmes for truck drivers in Andhra Pradesh, India. BMC Health Serv Res. 2009, 9 (82): 82-10.1186/1472-6963-9-82.CrossRefPubMedPubMedCentral
11.
go back to reference Murray CJL, Lopez AD, eds: The Global Burden of Disease. 1996, Cambridge, MA: Harvard University Press Murray CJL, Lopez AD, eds: The Global Burden of Disease. 1996, Cambridge, MA: Harvard University Press
12.
go back to reference Fox-Rushby JA, Hanson K: Calculating and presenting disability adjusted life years (DALYs) in cost-effectiveness analysis. Health Policy Plan. 2001, 16 (3): 326-331. 10.1093/heapol/16.3.326.CrossRefPubMed Fox-Rushby JA, Hanson K: Calculating and presenting disability adjusted life years (DALYs) in cost-effectiveness analysis. Health Policy Plan. 2001, 16 (3): 326-331. 10.1093/heapol/16.3.326.CrossRefPubMed
14.
go back to reference Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJL, eds: Global Burden of Disease and Risk Factors. 2006, Washington DC: The World Bank Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJL, eds: Global Burden of Disease and Risk Factors. 2006, Washington DC: The World Bank
15.
go back to reference Hira SK, Shroff HJ, Lanjewar DN, Dholkia YN, Bhatia VP, Dupont HL: The natural history of human immunodeficiency virus infection among adults in Mumbai. Natl Med J India. 2003, 16 (3): 126-131.PubMed Hira SK, Shroff HJ, Lanjewar DN, Dholkia YN, Bhatia VP, Dupont HL: The natural history of human immunodeficiency virus infection among adults in Mumbai. Natl Med J India. 2003, 16 (3): 126-131.PubMed
17.
18.
go back to reference The World Bank: Project appraisal document on a proposed credit in the amount of SDR 140.82 million to India for second national HIV/AIDS control project. Report No: 18918-IN. 1999, Washington DC: The World Bank The World Bank: Project appraisal document on a proposed credit in the amount of SDR 140.82 million to India for second national HIV/AIDS control project. Report No: 18918-IN. 1999, Washington DC: The World Bank
19.
go back to reference Fung IC, Guinness L, Vickerman P, Watts C, Vannela G, Vadhvana J, Foss AM, Malodia L, Gandhi M, Jani G: Modelling the impact and cost-effectiveness of the HIV intervention programme amongst commercial sex workers in Ahmedabad, Gujarat, India. BMC Public Health. 2007, 7 (195): 195-10.1186/1471-2458-7-195.CrossRefPubMedPubMedCentral Fung IC, Guinness L, Vickerman P, Watts C, Vannela G, Vadhvana J, Foss AM, Malodia L, Gandhi M, Jani G: Modelling the impact and cost-effectiveness of the HIV intervention programme amongst commercial sex workers in Ahmedabad, Gujarat, India. BMC Public Health. 2007, 7 (195): 195-10.1186/1471-2458-7-195.CrossRefPubMedPubMedCentral
20.
go back to reference Kumar M, Birch S, Maturana A, Gafni A: Economic evaluation of HIV screening in pregnant women attending antenatal clinics in India. Health Policy. 2006, 77 (2): 233-243. 10.1016/j.healthpol.2005.07.014.CrossRefPubMed Kumar M, Birch S, Maturana A, Gafni A: Economic evaluation of HIV screening in pregnant women attending antenatal clinics in India. Health Policy. 2006, 77 (2): 233-243. 10.1016/j.healthpol.2005.07.014.CrossRefPubMed
21.
go back to reference Dandona L, Dandona R: Drop of HIV estimate for India to less than half. Lancet. 2007, 370 (9602): 1811-1813. 10.1016/S0140-6736(07)61756-5.CrossRefPubMed Dandona L, Dandona R: Drop of HIV estimate for India to less than half. Lancet. 2007, 370 (9602): 1811-1813. 10.1016/S0140-6736(07)61756-5.CrossRefPubMed
22.
go back to reference Pandey A, Reddy DC, Ghys PD, Thomas M, Sahu D, Bhattacharya M, Maiti KD, Arnold F, Kant S, Khera A, et al: Improved estimates of India's HIV burden in 2006. Indian J Med Res. 2009, 129 (1): 50-58.PubMed Pandey A, Reddy DC, Ghys PD, Thomas M, Sahu D, Bhattacharya M, Maiti KD, Arnold F, Kant S, Khera A, et al: Improved estimates of India's HIV burden in 2006. Indian J Med Res. 2009, 129 (1): 50-58.PubMed
23.
go back to reference Directorate of Economics and Statistics: Statistical abstract of Andhra Pradesh. 2006, Hyderabad: Government of Andhra Pradesh Directorate of Economics and Statistics: Statistical abstract of Andhra Pradesh. 2006, Hyderabad: Government of Andhra Pradesh
24.
go back to reference World Health Organization: World Health Report: Reducing risks, promoting healthy life. 2002, Geneva: World Health Organization World Health Organization: World Health Report: Reducing risks, promoting healthy life. 2002, Geneva: World Health Organization
25.
go back to reference Chandrasekaran P, Dallabetta G, Loo V, Mills S, Saidel T, Adhikary R, Alary M, Lowndes CM, Boily MC, Moore J: Evaluation design for large-scale HIV prevention programmes: the case of Avahan, the India AIDS initiative. AIDS. 2008, 22 (Suppl 5): S1-15. 10.1097/01.aids.0000343760.70078.89.CrossRefPubMed Chandrasekaran P, Dallabetta G, Loo V, Mills S, Saidel T, Adhikary R, Alary M, Lowndes CM, Boily MC, Moore J: Evaluation design for large-scale HIV prevention programmes: the case of Avahan, the India AIDS initiative. AIDS. 2008, 22 (Suppl 5): S1-15. 10.1097/01.aids.0000343760.70078.89.CrossRefPubMed
Metadata
Title
Cost-effectiveness of HIV prevention interventions in Andhra Pradesh state of India
Authors
Lalit Dandona
SG Prem Kumar
G Anil Kumar
Rakhi Dandona
Publication date
01-12-2010
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2010
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/1472-6963-10-117

Other articles of this Issue 1/2010

BMC Health Services Research 1/2010 Go to the issue