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BMC Dermatology
Published in: BMC Dermatology 1/2014

Open Access 01-12-2014 | Research article

Risk factors for eczema in infants born in Cuba: a population-based cross-sectional study

Published in: BMC Dermatology | Issue 1/2014

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Abstract

Background

There is a concern that allergic disease in childhood is higher than expected in Cuba. The aim of this study was to determine the risk factors for eczema of infants aged 12–15 months living in Havana.

Methods

We used a cross-sectional epidemiological study design. Data on eczema symptoms and a wide range of lifestyle factors were collected by researcher administered questionnaires.

Results

Data were collected on 1956 children (96% response rate), of whom 672 (34%) were reported as having had eczema. Independent risk factors for eczema included young maternal age (adjusted odds ratio (OR) 0.98 per additional year of age; 95% confidence interval (CI) 0.97-0.99), child’s weight (OR 1.13 per additional kg; 95% CI: 1.03-1.25), insect sting allergy (OR 2.11; 95% CI: 1.33-3.35), rodents in the home (OR 1.39; 95% CI: 1.10-1.76), attendance at childcare facilities (OR 1.34: 95% CI: 1.05-1.70) and self-reported mould in the home (OR 1.23; 95% CI: 1.07-1.41). Infant exposure to paracetamol was associated with an increased risk of eczema even after adjustment for wheeze (OR 1.22; 95% CI: 1.03-1.46).

Conclusion

Despite a very different culture and environment, the consistency of these findings with those from more economically developed countries suggests potential causal associations. The association with paracetamol, even after adjustment for wheeze, suggests that intervention studies are required in young infants, to ascertain if this commonly used anti-pyretic medication increases allergic disease.
Appendix
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Metadata
Title
Risk factors for eczema in infants born in Cuba: a population-based cross-sectional study
Publication date
01-12-2014
Published in
BMC Dermatology / Issue 1/2014
Electronic ISSN: 1471-5945
DOI
https://doi.org/10.1186/1471-5945-14-6

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