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Published in: BMC Surgery 2/2013

Open Access 01-10-2013 | Research article

Health related quality of life in colorectal cancer patients: state of the art

Authors: Stefano Marventano, Maria Joao Forjaz, Giuseppe Grosso, Antonio Mistretta, Gabriele Giorgianni, Alessio Platania, Santi Gangi, Francesco Basile, Antonio Biondi

Published in: BMC Surgery | Special Issue 2/2013

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Abstract

Background

Colorectal cancer (CRC) is the third most commonly diagnosed cancer in males and the second in females with a progressive increase in prevalence in industrialized countries. The loss of health due to the cancer and/or the consequence of the treatment may result in psychophysical, functional and social impairment; all of these affect health-related quality of life (QoL).

Description

The most frequently CRC-specific QoL questionnaires is the FACT-C. QoL is not only important for the well-being of cancer patient but it also influences survival and response to therapy. Many studies investigated various determinants involved in the assessment of QoL in CRC, suggesting that symptoms, surgical procedures and the number of comorbidity significantly affected QoL.

Conclusion

Despite that CRC patients have a relatively good QoL compared with the general population, a wide range of intervention could be undertaken to improve their QoL. The finding of this review may be useful for cancer clinicians in taking therapy and surveillance-related decisions. However, future research should be directed to large-scale prospective studies using well validated QoL instruments to facilitate comparison of results.
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Metadata
Title
Health related quality of life in colorectal cancer patients: state of the art
Authors
Stefano Marventano
Maria Joao Forjaz
Giuseppe Grosso
Antonio Mistretta
Gabriele Giorgianni
Alessio Platania
Santi Gangi
Francesco Basile
Antonio Biondi
Publication date
01-10-2013
Publisher
BioMed Central
Published in
BMC Surgery / Issue Special Issue 2/2013
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/1471-2482-13-S2-S15

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