Skip to main content
Top
Published in: BMC Musculoskeletal Disorders 1/2006

Open Access 01-12-2006 | Research article

The association of comorbidities, utilization and costs for patients identified with low back pain

Authors: Debra P Ritzwoller, Laurie Crounse, Susan Shetterly, Dale Rublee

Published in: BMC Musculoskeletal Disorders | Issue 1/2006

Login to get access

Abstract

Background

Existing studies have examined the high prevalence of LBP along with the high treatment costs of patients with low back pain (LBP). Various factors have been shown to be correlated or predictive of chronic or episodic LBP including the characteristics of the initial episode, pain, comorbid conditions, psychosocial issues, and opiate use. This study replicates and extends earlier studies by examining the association of patient characteristics including baseline comorbidities with patterns of healthcare service use and cost.

Methods

This is a retrospective analysis of measures of comorbidities, healthcare use, and cost for patients identified with LBP, stratified by the number of LBP episodes. Administrative data associated with outpatient and hospital based care for the years 1996 through 2001, were used to identify adult patients with LBP. LBP patients continuously enrolled for 12 months prior and 24 months after their initial LBP event were included in the study. A LBP episode was identified as the number of 30-day periods where a patient had one or more healthcare events with a diagnosis consistent with LBP. Chi-square and multivariate regression analyses were employed to estimate the variation in utilization and costs.

Results

Of 16,567 patients enrolled, 67% were identified with only one LBP episode and 4.5% had ≥6. The prevalence of comorbidities, analgesic use, and healthcare service use, varied by the number of back pain episodes. Diabetes, rheumatoid arthritis, anxiety, psychotic illness, depression, use of opiates and NSAIDs were associated with significant incremental increases in costs (P < .003).

Conclusion

Physical and mental health co-morbidities and measures of analgesic use were associated with chronicity, healthcare utilization and costs. Given the association of comorbidities and cost for patients with LBP, management approaches that are effective across chronic illnesses may prove to be beneficial for high cost patients identified with LBP.
Appendix
Available only for authorised users
Literature
1.
2.
go back to reference Cassidy JD, Carroll LJ, Cote P: The Saskatchewan Health and Back Pain Survey. Spine. 1998, 23: 1860-1867. 10.1097/00007632-199809010-00012.CrossRefPubMed Cassidy JD, Carroll LJ, Cote P: The Saskatchewan Health and Back Pain Survey. Spine. 1998, 23: 1860-1867. 10.1097/00007632-199809010-00012.CrossRefPubMed
3.
go back to reference Von Korff M, Deyo RA, Cherkin D, Barlow W: Back pain in primary care outcomes at 1 year. Spine. 1993, 18 (7): 855-62.CrossRefPubMed Von Korff M, Deyo RA, Cherkin D, Barlow W: Back pain in primary care outcomes at 1 year. Spine. 1993, 18 (7): 855-62.CrossRefPubMed
4.
go back to reference Carey TS, Garrett JM, Jackman AM: Beyond the good prognosis. Examination of an inception cohort of patients with chronic low back pain. Spine. 2000, 25 (1): 115-20. 10.1097/00007632-200001010-00019.CrossRefPubMed Carey TS, Garrett JM, Jackman AM: Beyond the good prognosis. Examination of an inception cohort of patients with chronic low back pain. Spine. 2000, 25 (1): 115-20. 10.1097/00007632-200001010-00019.CrossRefPubMed
5.
go back to reference Pai S, Sundaram LJ: Low back pain: an economic assessment in the United States. Orthop Clin North Am. 2004, 35 (1): 1-5. 10.1016/S0030-5898(03)00101-9.CrossRefPubMed Pai S, Sundaram LJ: Low back pain: an economic assessment in the United States. Orthop Clin North Am. 2004, 35 (1): 1-5. 10.1016/S0030-5898(03)00101-9.CrossRefPubMed
6.
go back to reference Williams DA, Feuerstein M, Durbin D, Pezzullo J: Healthcare and indemnity costs across the natural history of disability in occupational low back pain. Spine. 23 (21): 2329-36. 10.1097/00007632-199811010-00016. 1998 Nov 1; Williams DA, Feuerstein M, Durbin D, Pezzullo J: Healthcare and indemnity costs across the natural history of disability in occupational low back pain. Spine. 23 (21): 2329-36. 10.1097/00007632-199811010-00016. 1998 Nov 1;
7.
go back to reference Engel CC, Von Korff M, Katon WJ: Back Pain in Primary-Care: Predictors of High Health-Care Costs. Pain. 1996, 65: 197-204. 10.1016/0304-3959(95)00164-6.CrossRefPubMed Engel CC, Von Korff M, Katon WJ: Back Pain in Primary-Care: Predictors of High Health-Care Costs. Pain. 1996, 65: 197-204. 10.1016/0304-3959(95)00164-6.CrossRefPubMed
8.
go back to reference Maetzel A, Li L: The economic burden of low back pain: a review of studies published between 1996 and 2001. Best Pract Res Clin Rheumatol. 2002, 16 (1): 23-30. 10.1053/berh.2001.0204.CrossRefPubMed Maetzel A, Li L: The economic burden of low back pain: a review of studies published between 1996 and 2001. Best Pract Res Clin Rheumatol. 2002, 16 (1): 23-30. 10.1053/berh.2001.0204.CrossRefPubMed
9.
go back to reference Arnau JM, Vallano A, Lopez A, Pellise F, Delgado MJ, Prat N: A critical review of guidelines for low back pain treatment. Eur Spine J. 2006, 15 (5): 543-53. 10.1007/s00586-005-1027-y. Epub 2005 Oct 11.CrossRefPubMed Arnau JM, Vallano A, Lopez A, Pellise F, Delgado MJ, Prat N: A critical review of guidelines for low back pain treatment. Eur Spine J. 2006, 15 (5): 543-53. 10.1007/s00586-005-1027-y. Epub 2005 Oct 11.CrossRefPubMed
11.
go back to reference Neubauer E, Junge A, Pirron P, Seemann H, Schiltenwolf M: HKF-R 10 – Screening for predicting chronicity in acute low back pain (LBP): A prospective clinical trial. Eur J Pain. 2006, 10 (6): 559-66. 10.1016/j.ejpain.2005.08.002. Epub 2005 Oct 3.CrossRefPubMed Neubauer E, Junge A, Pirron P, Seemann H, Schiltenwolf M: HKF-R 10 – Screening for predicting chronicity in acute low back pain (LBP): A prospective clinical trial. Eur J Pain. 2006, 10 (6): 559-66. 10.1016/j.ejpain.2005.08.002. Epub 2005 Oct 3.CrossRefPubMed
12.
go back to reference Bouter LM, van Tulder MW, Koes BW: Methodologic issues in low back pain research in primary care. Spine. 23 (18): 2014-20. 10.1097/00007632-199809150-00019. 1998, Sep 15; Bouter LM, van Tulder MW, Koes BW: Methodologic issues in low back pain research in primary care. Spine. 23 (18): 2014-20. 10.1097/00007632-199809150-00019. 1998, Sep 15;
13.
go back to reference Wasiak R, Pransky GS, Webster BS: Methodological challenges in studying recurrence of low back pain. J Occup Rehabil. 2003, 13 (1): 21-31. 10.1023/A:1021893706683.CrossRefPubMed Wasiak R, Pransky GS, Webster BS: Methodological challenges in studying recurrence of low back pain. J Occup Rehabil. 2003, 13 (1): 21-31. 10.1023/A:1021893706683.CrossRefPubMed
14.
go back to reference Cedraschi C, Robert J, Goerg D, Perrin E, Fischer W, Vischer TL: Is chronic non-specific low back pain chronic? Definitions of a problem and problems of a definition. Br J Gen Pract. 1999, 49 (442): 358-62.PubMedPubMedCentral Cedraschi C, Robert J, Goerg D, Perrin E, Fischer W, Vischer TL: Is chronic non-specific low back pain chronic? Definitions of a problem and problems of a definition. Br J Gen Pract. 1999, 49 (442): 358-62.PubMedPubMedCentral
15.
go back to reference de Vet HC, Heymans MW, Dunn KM, Pope DP, van der Beek AJ, Macfarlane GJ, Bouter LM, Croft PR: Episodes of low back pain: a proposal for uniform definitions to be used in research. Spine. 27 (21): 2409-16. 10.1097/00007632-200211010-00016. 2002 Nov 1; de Vet HC, Heymans MW, Dunn KM, Pope DP, van der Beek AJ, Macfarlane GJ, Bouter LM, Croft PR: Episodes of low back pain: a proposal for uniform definitions to be used in research. Spine. 27 (21): 2409-16. 10.1097/00007632-200211010-00016. 2002 Nov 1;
16.
go back to reference Valat JP, Goupille P, Rozenberg S, Urbinelli R, Allaert F: Spine group of the Societe Francaise. Acute low back pain: predictive index of chronicity from a cohort of 2487 subjects. Spine Group of the Societe Francaise de Rhumatologie. Joint Bone Spine. 2000, 67 (5): 456-61.PubMed Valat JP, Goupille P, Rozenberg S, Urbinelli R, Allaert F: Spine group of the Societe Francaise. Acute low back pain: predictive index of chronicity from a cohort of 2487 subjects. Spine Group of the Societe Francaise de Rhumatologie. Joint Bone Spine. 2000, 67 (5): 456-61.PubMed
17.
go back to reference Carragee EJ, Alamin TF, Miller JL, Carragee JM: Discographic, MRI and psychosocial determinants of low back pain disability and remission: a prospective study in subjects with benign persistent back pain. Spine J. 2005, 5 (1): 24-35. 10.1016/j.spinee.2004.05.250.CrossRefPubMed Carragee EJ, Alamin TF, Miller JL, Carragee JM: Discographic, MRI and psychosocial determinants of low back pain disability and remission: a prospective study in subjects with benign persistent back pain. Spine J. 2005, 5 (1): 24-35. 10.1016/j.spinee.2004.05.250.CrossRefPubMed
18.
go back to reference Hasenbring M, Hallner D, Klasen B: Psychological mechanisms in the transition from acute to chronic pain: over- or underrated?. Schmerz. 2001, 15 (6): 442-7. 10.1007/s004820100030.CrossRefPubMed Hasenbring M, Hallner D, Klasen B: Psychological mechanisms in the transition from acute to chronic pain: over- or underrated?. Schmerz. 2001, 15 (6): 442-7. 10.1007/s004820100030.CrossRefPubMed
19.
20.
go back to reference Vogt MT, Kwoh CK, Cope DK, Osial TA, Culyba M, Starz TW: Analgesic usage for low back pain: impact on healthcare costs and service use. Spine. 30 (9): 1075-81. 10.1097/01.brs.0000160843.77091.07. 2005 May 1; Vogt MT, Kwoh CK, Cope DK, Osial TA, Culyba M, Starz TW: Analgesic usage for low back pain: impact on healthcare costs and service use. Spine. 30 (9): 1075-81. 10.1097/01.brs.0000160843.77091.07. 2005 May 1;
21.
go back to reference Hestbaek L, Leboeuf-Yde C, Manniche C: Is low back pain part of a general health pattern or is it a separate and distinctive entity? A critical literature review of comorbidity with low back pain. J Manipulative Physiol Ther. 2003, 26 (4): 243-52. 10.1016/S0161-4754(03)00003-4.CrossRefPubMed Hestbaek L, Leboeuf-Yde C, Manniche C: Is low back pain part of a general health pattern or is it a separate and distinctive entity? A critical literature review of comorbidity with low back pain. J Manipulative Physiol Ther. 2003, 26 (4): 243-52. 10.1016/S0161-4754(03)00003-4.CrossRefPubMed
22.
go back to reference Nordin M, Hiebert R, Pietrek M, Alexander M, Crane M, Lewis S: Association of comorbidity and outcome in episodes of nonspecific low back pain in occupational populations. J Occup Environ Med. 2002, 44 (7): 677-84.CrossRefPubMed Nordin M, Hiebert R, Pietrek M, Alexander M, Crane M, Lewis S: Association of comorbidity and outcome in episodes of nonspecific low back pain in occupational populations. J Occup Environ Med. 2002, 44 (7): 677-84.CrossRefPubMed
23.
go back to reference Cherkin DC, Deyo RA, Volinn E, Loeser JD: Use of international Classification of Diseases (ICD-9-CM) to identify hospitalizations for mechanical low back problems in administrative databases. Spine. 1992, 17: 817-25.CrossRefPubMed Cherkin DC, Deyo RA, Volinn E, Loeser JD: Use of international Classification of Diseases (ICD-9-CM) to identify hospitalizations for mechanical low back problems in administrative databases. Spine. 1992, 17: 817-25.CrossRefPubMed
24.
go back to reference St Anthony's DRG Guidebook. 2000, St Anthony Publishing, Reston VA St Anthony's DRG Guidebook. 2000, St Anthony Publishing, Reston VA
25.
go back to reference Fishman PA, Goodman MJ, Hornbrook MC, Meenan RT, Bachman DJ, O'Keeffe Rosetti MC: Risk adjustment using automated ambulatory pharmacy data: the RxRisk model. Med Care. 2003, 41 (1): 84-99. 10.1097/00005650-200301000-00011.CrossRefPubMed Fishman PA, Goodman MJ, Hornbrook MC, Meenan RT, Bachman DJ, O'Keeffe Rosetti MC: Risk adjustment using automated ambulatory pharmacy data: the RxRisk model. Med Care. 2003, 41 (1): 84-99. 10.1097/00005650-200301000-00011.CrossRefPubMed
26.
go back to reference Clark DO, Von Korff M, Saunders K, Baluch WM, Simon GE: A chronic disease score with empirically derived weights. Med Care. 1995, 33: 783-95. 10.1097/00005650-199508000-00004.CrossRefPubMed Clark DO, Von Korff M, Saunders K, Baluch WM, Simon GE: A chronic disease score with empirically derived weights. Med Care. 1995, 33: 783-95. 10.1097/00005650-199508000-00004.CrossRefPubMed
27.
go back to reference Johnson RE, Hornbrook MC, Nichols GA: Replicating the chronic disease score (CDS) from automated pharmacy data. J Clin Epidemiol. 1994, 47: 1191-1199. 10.1016/0895-4356(94)90106-6.CrossRefPubMed Johnson RE, Hornbrook MC, Nichols GA: Replicating the chronic disease score (CDS) from automated pharmacy data. J Clin Epidemiol. 1994, 47: 1191-1199. 10.1016/0895-4356(94)90106-6.CrossRefPubMed
29.
go back to reference Anderson LH, Martinson BC, Crain AL, Pronk NP, Whitebird RR, O"Connor PJ, Fine LJ: Health care charges associated with physical inactivity, overweight, and obesity. Prev Chronic Dis. 2005, 2 (4): A09-Epub 2005PubMedPubMedCentral Anderson LH, Martinson BC, Crain AL, Pronk NP, Whitebird RR, O"Connor PJ, Fine LJ: Health care charges associated with physical inactivity, overweight, and obesity. Prev Chronic Dis. 2005, 2 (4): A09-Epub 2005PubMedPubMedCentral
30.
go back to reference Diehr P, Yanez D, Ash A, Hornbrook M, Lin DY: Methods for analyzing health care utilization and costs. Annu Rev Public Health. 1999, 20: 125-44. 10.1146/annurev.publhealth.20.1.125.CrossRefPubMed Diehr P, Yanez D, Ash A, Hornbrook M, Lin DY: Methods for analyzing health care utilization and costs. Annu Rev Public Health. 1999, 20: 125-44. 10.1146/annurev.publhealth.20.1.125.CrossRefPubMed
31.
go back to reference Harvey AC: Estimating Regression Models with Multiplicative Heteroscedasticity, Econometrica. Econometrica. 1976, 44 (3): 461-465. 10.2307/1913974.CrossRef Harvey AC: Estimating Regression Models with Multiplicative Heteroscedasticity, Econometrica. Econometrica. 1976, 44 (3): 461-465. 10.2307/1913974.CrossRef
32.
go back to reference Kronick R, Dreyfus T, Lee L, Zhou Z: Diagnostic risk adjustment for Medicaid: the disability payment system. Healthcare Financ Rev. Spring. 1996, 17 (3): 7-33. Kronick R, Dreyfus T, Lee L, Zhou Z: Diagnostic risk adjustment for Medicaid: the disability payment system. Healthcare Financ Rev. Spring. 1996, 17 (3): 7-33.
33.
go back to reference Gilmer T, Kronick R, Fishman P, Ganiats TG: The Medicaid Rx model: pharmacy-based risk adjustment for public programs. Med Care. 2001, 39 (11): 1188-202. 10.1097/00005650-200111000-00006.CrossRefPubMed Gilmer T, Kronick R, Fishman P, Ganiats TG: The Medicaid Rx model: pharmacy-based risk adjustment for public programs. Med Care. 2001, 39 (11): 1188-202. 10.1097/00005650-200111000-00006.CrossRefPubMed
34.
go back to reference Pincus T, Burton AK, Vogel S, Field AP: A systematic review of psychological factors as predictors of chronicity/disability in prospective cohorts of low back pain. Spine. 27 (5): E109-20. 10.1097/00007632-200203010-00017. 2002 Mar 1; Pincus T, Burton AK, Vogel S, Field AP: A systematic review of psychological factors as predictors of chronicity/disability in prospective cohorts of low back pain. Spine. 27 (5): E109-20. 10.1097/00007632-200203010-00017. 2002 Mar 1;
35.
go back to reference Valat JP, Goupille P, Vedere V: Low back pain: risk factors for chronicity. Rev Rhum Engl Ed. 1997, 64 (3): 189-94.PubMed Valat JP, Goupille P, Vedere V: Low back pain: risk factors for chronicity. Rev Rhum Engl Ed. 1997, 64 (3): 189-94.PubMed
36.
go back to reference Herndon CM, Kalauokalani DA, Cunningham AJ, Jackson KC, Dunteman ED: Anticipating and treating opioid-associated adverse effects. Expert Opin Drug Saf. 2003, 2 (3): 305-19.PubMed Herndon CM, Kalauokalani DA, Cunningham AJ, Jackson KC, Dunteman ED: Anticipating and treating opioid-associated adverse effects. Expert Opin Drug Saf. 2003, 2 (3): 305-19.PubMed
37.
go back to reference Acute Pain Management Guideline Panel. Acute pain management: Operative or medical procedures and trauma. Clinical Practice Guideline. AHCPR Pub. No. 92–0032. 1992, Rockville, MD: Agency for Healthcare Policy and Research, Public Health Service, U.S. Department of Health and Human Services Acute Pain Management Guideline Panel. Acute pain management: Operative or medical procedures and trauma. Clinical Practice Guideline. AHCPR Pub. No. 92–0032. 1992, Rockville, MD: Agency for Healthcare Policy and Research, Public Health Service, U.S. Department of Health and Human Services
38.
go back to reference Goulding MR: Inappropriate medication prescribing for elderly ambulatory care patients. Arch Intern Med. 2004, 164 (3): 305-312. 10.1001/archinte.164.3.305.CrossRefPubMed Goulding MR: Inappropriate medication prescribing for elderly ambulatory care patients. Arch Intern Med. 2004, 164 (3): 305-312. 10.1001/archinte.164.3.305.CrossRefPubMed
39.
go back to reference Kominski GF, Heslin KC, Morgenstern H, Hurwitz EL, Harber PI: Economic evaluation of four treatments for low-back pain: results from a randomized controlled trial. Med Care. 2005, 43 (5): 428-35. 10.1097/01.mlr.0000160379.12806.08.CrossRefPubMed Kominski GF, Heslin KC, Morgenstern H, Hurwitz EL, Harber PI: Economic evaluation of four treatments for low-back pain: results from a randomized controlled trial. Med Care. 2005, 43 (5): 428-35. 10.1097/01.mlr.0000160379.12806.08.CrossRefPubMed
40.
go back to reference Carey TS, Freburger J: Prudence, nihilism, and the treatment of low-back pain. Med Care. 2005, 43 (5): 425-7. 10.1097/01.mlr.0000163859.24721.79.CrossRefPubMed Carey TS, Freburger J: Prudence, nihilism, and the treatment of low-back pain. Med Care. 2005, 43 (5): 425-7. 10.1097/01.mlr.0000163859.24721.79.CrossRefPubMed
41.
go back to reference Wagner EH: Chronic disease management: What will it take to improve care for chronic illness?. Effective Clinical Practice. 1998, 1: 2-4.PubMed Wagner EH: Chronic disease management: What will it take to improve care for chronic illness?. Effective Clinical Practice. 1998, 1: 2-4.PubMed
42.
go back to reference Glasgow RE, Funnell MM, Bonomi AE, Davis C, Beckham V, Wagner EH: Self-management aspects of the Improving Chronic Illness Care Breakthrough Series: Implementation with diabetes and heart failure teams. Annals of Behavioral Medicine. 2002, 24: 80-87. 10.1207/S15324796ABM2402_04.CrossRefPubMed Glasgow RE, Funnell MM, Bonomi AE, Davis C, Beckham V, Wagner EH: Self-management aspects of the Improving Chronic Illness Care Breakthrough Series: Implementation with diabetes and heart failure teams. Annals of Behavioral Medicine. 2002, 24: 80-87. 10.1207/S15324796ABM2402_04.CrossRefPubMed
Metadata
Title
The association of comorbidities, utilization and costs for patients identified with low back pain
Authors
Debra P Ritzwoller
Laurie Crounse
Susan Shetterly
Dale Rublee
Publication date
01-12-2006
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2006
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/1471-2474-7-72

Other articles of this Issue 1/2006

BMC Musculoskeletal Disorders 1/2006 Go to the issue