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BMC Musculoskeletal Disorders
Published in: BMC Musculoskeletal Disorders 1/2005

Open Access 01-12-2005 | Research article

Abdominal fat and hip fracture risk in the elderly: The Dubbo Osteoporosis Epidemiology Study

Authors: Nguyen D Nguyen, Chatlert Pongchaiyakul, Jacqueline R Center, John A Eisman, Tuan V Nguyen

Published in: BMC Musculoskeletal Disorders | Issue 1/2005

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Abstract

Background

Fat mass, which is a major component of body weight, is directly related to bone mineral density and reduced fracture risk. It is not known whether abdominal fat is associated with hip fracture. The present study was designed to examine the association between abdominal fat and hip fracture in women and men aged 60+ years.

Methods

This was a nested case-control study with one fracture case being matched with two controls of the same age. In women 63 cases were matched with 126 controls, and in men 26 cases were matched with 52 controls. Hip fracture was confirmed by X-ray and personal interview. Other measurements included weight, height, body mass index (BMI), abdominal fat, and femoral neck bone density (FNBMD). Conditional logistic regression model was used to analyse data.

Results

The odds ratio of hip fracture risk associated with each 10% lower abdominal fat was 1.5 (95% CI, 1.1 to 2.1) in women and 1.2 (95% CI, 0.7 to 2.0) in men. However after adjusting for FNBMD or body weight, the abdominal fat-fracture association was no longer statistically significant. Similarly, body weight and BMI was each significantly associated with hip fracture risk (in women), but after taking with account the effect of FNBMD, the association become statistically non-significant.

Conclusion

Lower abdominal fat was associated with an increased risk of hip fracture in elderly women, but the association was not independent of FNBMD or weight. The contribution of abdominal fat to hip fracture risk is likely to be modest.
Appendix
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Metadata
Title
Abdominal fat and hip fracture risk in the elderly: The Dubbo Osteoporosis Epidemiology Study
Authors
Nguyen D Nguyen
Chatlert Pongchaiyakul
Jacqueline R Center
John A Eisman
Tuan V Nguyen
Publication date
01-12-2005
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2005
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/1471-2474-6-11

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