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BMC Musculoskeletal Disorders
Published in: BMC Musculoskeletal Disorders 1/2015

Open Access 01-12-2015 | Meeting abstract

Musculoskeletal health from the “One Medicine” perspective – what can we learn from large and small animal models (with emphasis on articular cartilage)?

Authors: P René van Weeren, Marianna A Tryfonidou

Published in: BMC Musculoskeletal Disorders | Special Issue 1/2015

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Excerpt

In human medicine musculoskeletal diseases rank (together with mental disorders) first in reasons for occupational disability and have a huge impact on both quality of life and overall healthcare costs[1]. The current increase in life expectancy, together with decreasing societal acceptance of impaired mobility, have strongly pushed musculoskeletal research in recent years. …
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Palazzo C, Ravaud JF, Papelard A, Ravaud P, Poiraudeau S: The burden of musculoskeletal conditions. PLoS One. 2014, 9 (3): e90633-24595187, 3942474, 10.1371/journal.pone.0090633CrossRefPubMedPubMedCentral
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Cook JL, Hung CT, Kuroki K, Stoker AM, Cook CR, Pfeiffer FM, Sherman SL, Stannard JP: Animal models of cartilage repair. Bone Joint Res. 2;3 (4): 89-94.
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Malda J, de Grauw JC, Benders KEM, Kik MJL, van de Lest CA, Creemers LB, Dhert WJA, van Weeren PR: Of mice, men and elephants: the relation between articular cartilage thickness and body mass. PLoS One. 2013, 8 (2): e57683-23437402, 1:CAS:528:DC%2BC3sXjs12nt78%3D, 3578797, 10.1371/journal.pone.0057683CrossRefPubMedPubMedCentral
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Bergknut N, Rutges JP, Kranenburg HJ, Smolders LA, Hagman R, Smidt HJ, Lagerstedt AS, Penning LC, Voorhout G, Hazewinkel HA, Grinwis GC, Creemers LB, Meij BP, Dhert WJ: The dog as an animal model for intervertebral disc degeneration?. Spine. 2012, 37 (5): 351-8. 21544011, 10.1097/BRS.0b013e31821e5665CrossRefPubMed
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McIlwraith C, Frisbie DD, Kawcak CE: The horse as a model of naturally occurring osteoarthritis. Bone Joint Res. 2012, 1 (11): 297-309. 23610661, 1:STN:280:DC%2BC3srns1GhtQ%3D%3D, 3626203, 10.1302/2046-3758.111.2000132CrossRefPubMedPubMedCentral
Metadata
Title
Musculoskeletal health from the “One Medicine” perspective – what can we learn from large and small animal models (with emphasis on articular cartilage)?
Authors
P René van Weeren
Marianna A Tryfonidou
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue Special Issue 1/2015
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/1471-2474-16-S1-S6

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