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Published in: BMC Musculoskeletal Disorders 1/2012

Open Access 01-12-2012 | Research article

Rheumatoid arthritis and sexuality: A patient survey in France

Authors: Gisela Kobelt, Brigitte Texier-Richard, Sylvain Mimoun, Anne-Sophie Woronoff, David-Romain Bertholon, Aleth Perdriger, Yves Maugars, Bernard Combe

Published in: BMC Musculoskeletal Disorders | Issue 1/2012

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Abstract

Background

The objective of this study was to evaluate the impact of rheumatoid arthritis (RA) on patients’ sexuality and identify disease and other factors such as fatigue that most influence sexual relationships.

Methods

A specific pretested questionnaire was sent to all members of a French patient association (ANDAR). Questions related to demographics, disease status, quality of life (utility, EQ-5D), pain, psychological status (mood), fatigue and emotional and sexual relationships. To isolate the impact of RA, an attempt was made to include a matched sample from the general population.

Results

The analysis included 1271 patients, but only 70 controls agreed to participate and comparisons should therefore be considered with caution. The two groups were similar in terms of age, gender distribution, living conditions and diseases other than RA. However, patients scored worse for global health, mood, fatigue, had a lower utility (0.55 versus 0.65). Controls were more active sexually (69% versus 63%), in particular women (71% versus 60%). Age, gender, living alone, physical function and mood were significant predictors for being sexually active for patients; for controls, age and overall quality of life (utility) were significant predictors.

Conclusions

While it is known that RA has a negative impact on patients’ sexuality, there have been few attempts to quantify the problem. Our study highlights the negative impact of RA on patients’ sexuality, and triggers the question how to include this aspect into care.
Literature
1.
go back to reference Thompson M, Leighton-Read J, Hutchings C, Paterson M, Jr EH: The Cost Effectiveness of Auranofin. Results of a Randomized Clinical Trial. Journal of Rheumatology. 1988, 15: 35-42.PubMed Thompson M, Leighton-Read J, Hutchings C, Paterson M, Jr EH: The Cost Effectiveness of Auranofin. Results of a Randomized Clinical Trial. Journal of Rheumatology. 1988, 15: 35-42.PubMed
2.
go back to reference Kalyoncu U, Dougados M, Daures JP, Gossec L: Reporting of patient-reported outcomes in recent trials in rheumatoid arthritis: a systematic literature review. Ann Rheum Dis. 2009, 68: 183-90. 10.1136/ard.2007.084848.CrossRefPubMed Kalyoncu U, Dougados M, Daures JP, Gossec L: Reporting of patient-reported outcomes in recent trials in rheumatoid arthritis: a systematic literature review. Ann Rheum Dis. 2009, 68: 183-90. 10.1136/ard.2007.084848.CrossRefPubMed
3.
go back to reference Kobelt G, Eberhardt K, Jönsson L, Jönsson B: Economic consequences of the progression of rheumatoid arthritis in Sweden. Arthritis & Rheumatism. 1999, 42: 347-56. 10.1002/1529-0131(199902)42:2<347::AID-ANR18>3.0.CO;2-P.CrossRef Kobelt G, Eberhardt K, Jönsson L, Jönsson B: Economic consequences of the progression of rheumatoid arthritis in Sweden. Arthritis & Rheumatism. 1999, 42: 347-56. 10.1002/1529-0131(199902)42:2<347::AID-ANR18>3.0.CO;2-P.CrossRef
4.
go back to reference Kobelt G, Andlin-Sobocki P, Maksymowych WP: Costs and quality of life of patients with ankylosing spondylitis in Canada. J Rheumatol. 2006, 33: 289-95.PubMed Kobelt G, Andlin-Sobocki P, Maksymowych WP: Costs and quality of life of patients with ankylosing spondylitis in Canada. J Rheumatol. 2006, 33: 289-95.PubMed
5.
go back to reference Gulfe A, Kristensen LE, Saxne T, Jacobsson LT, Petersson IF, Geborek P: Rapid and sustained health utility gain in anti-TNF treated inflammatory arthritis. 2009, Observational data during seven years in southern Sweden, Ann Rheum Dis Gulfe A, Kristensen LE, Saxne T, Jacobsson LT, Petersson IF, Geborek P: Rapid and sustained health utility gain in anti-TNF treated inflammatory arthritis. 2009, Observational data during seven years in southern Sweden, Ann Rheum Dis
6.
go back to reference Pouchot J, Kherani RB, Brant R: Determination of the minimal clinically important difference for seven fatigue measures in rheumatoid arthritis. J Clin Epidemiol. 2008, 61: 705-13. 10.1016/j.jclinepi.2007.08.016.CrossRefPubMedPubMedCentral Pouchot J, Kherani RB, Brant R: Determination of the minimal clinically important difference for seven fatigue measures in rheumatoid arthritis. J Clin Epidemiol. 2008, 61: 705-13. 10.1016/j.jclinepi.2007.08.016.CrossRefPubMedPubMedCentral
7.
go back to reference Mayoux-Benhamou MA: Fatigue and rheumatoid arthritis. Ann Readapt Med Phys. 2006, 49 (301–4): 85-8. Mayoux-Benhamou MA: Fatigue and rheumatoid arthritis. Ann Readapt Med Phys. 2006, 49 (301–4): 85-8.
8.
go back to reference Fifield J, McQuinnan J, Tennan H: History of affective disorder and temporal trajectory of fatigue in rheumatoid arthritis. Ann Behavioral Med. 2001, 23: 34-41. 10.1207/S15324796ABM2301_6.CrossRef Fifield J, McQuinnan J, Tennan H: History of affective disorder and temporal trajectory of fatigue in rheumatoid arthritis. Ann Behavioral Med. 2001, 23: 34-41. 10.1207/S15324796ABM2301_6.CrossRef
9.
go back to reference Pollard LC, Choy EH, Gonzalez J, Khoshaba B, Scott DL: Fatigue in rheumatoid arthritis reflects pain, not disease activity. Rheumatology (Oxford). 2006, 45: 885-9. 10.1093/rheumatology/kel021.CrossRef Pollard LC, Choy EH, Gonzalez J, Khoshaba B, Scott DL: Fatigue in rheumatoid arthritis reflects pain, not disease activity. Rheumatology (Oxford). 2006, 45: 885-9. 10.1093/rheumatology/kel021.CrossRef
10.
go back to reference Hewlett S, Hehir M, Kirwan JR: Measuring fatigue in rheumatoid arthritis: a systematic review of scales in use. Arthritis Rheum. 2007, 57: 429-39. 10.1002/art.22611.CrossRefPubMed Hewlett S, Hehir M, Kirwan JR: Measuring fatigue in rheumatoid arthritis: a systematic review of scales in use. Arthritis Rheum. 2007, 57: 429-39. 10.1002/art.22611.CrossRefPubMed
11.
go back to reference Wolfe F, Michaud K: Predicting depression in rheumatoid arthritis: the signal importance of pain extent and fatigue, and comorbidity. Arthritis Rheum. 2009, 61: 667-73. 10.1002/art.24428.CrossRefPubMed Wolfe F, Michaud K: Predicting depression in rheumatoid arthritis: the signal importance of pain extent and fatigue, and comorbidity. Arthritis Rheum. 2009, 61: 667-73. 10.1002/art.24428.CrossRefPubMed
12.
go back to reference Areskoug-Josefsson K, Oberg U: A literature review of the sexual health of women with rheumatoid arthritis. Musculoskeletal Care. 2009, 7: 219-26. 10.1002/msc.152.CrossRefPubMed Areskoug-Josefsson K, Oberg U: A literature review of the sexual health of women with rheumatoid arthritis. Musculoskeletal Care. 2009, 7: 219-26. 10.1002/msc.152.CrossRefPubMed
13.
go back to reference Tristano AG: The impact of rheumatic diseases on sexual function. Rheumatol Int. 2009, 29: 853-60. 10.1007/s00296-009-0850-6.CrossRefPubMed Tristano AG: The impact of rheumatic diseases on sexual function. Rheumatol Int. 2009, 29: 853-60. 10.1007/s00296-009-0850-6.CrossRefPubMed
14.
go back to reference Helland Y, Dagfinrud H, Kvien TK: Perceived influence of health status on sexual activity in RA patients: associations with demographic and disease-related variables. Scand J Rheumatol. 2008, 37: 194-9. 10.1080/03009740701867349.CrossRefPubMed Helland Y, Dagfinrud H, Kvien TK: Perceived influence of health status on sexual activity in RA patients: associations with demographic and disease-related variables. Scand J Rheumatol. 2008, 37: 194-9. 10.1080/03009740701867349.CrossRefPubMed
15.
go back to reference van Berlo WT, van de Wiel HB, Taal E, Rasker JJ, Weijmar Schultz WC, van Rijswijk MH: Sexual functioning of people with rheumatoid arthritis: a multicenter study. Clin Rheumatol. 2007, 26: 30-8. 10.1007/s10067-006-0216-3.CrossRefPubMed van Berlo WT, van de Wiel HB, Taal E, Rasker JJ, Weijmar Schultz WC, van Rijswijk MH: Sexual functioning of people with rheumatoid arthritis: a multicenter study. Clin Rheumatol. 2007, 26: 30-8. 10.1007/s10067-006-0216-3.CrossRefPubMed
16.
go back to reference Pouchot J, Le Parc JM, Queffelec L, Sichere P, Flinois A: Perceptions in 7700 patients with rheumatoid arthritis compared to their families and physicians. Joint Bone Spine. 2007, 74: 622-6. 10.1016/j.jbspin.2006.11.024.CrossRefPubMed Pouchot J, Le Parc JM, Queffelec L, Sichere P, Flinois A: Perceptions in 7700 patients with rheumatoid arthritis compared to their families and physicians. Joint Bone Spine. 2007, 74: 622-6. 10.1016/j.jbspin.2006.11.024.CrossRefPubMed
17.
go back to reference Kobelt G, Woronoff AS, Richard B, Peeters P, Sany J: Disease status, costs and quality of life of patients with rheumatoid arthritis in France: the ECO-PR Study. Joint Bone Spine. 2008, 75: 408-15. 10.1016/j.jbspin.2007.07.015.CrossRefPubMed Kobelt G, Woronoff AS, Richard B, Peeters P, Sany J: Disease status, costs and quality of life of patients with rheumatoid arthritis in France: the ECO-PR Study. Joint Bone Spine. 2008, 75: 408-15. 10.1016/j.jbspin.2007.07.015.CrossRefPubMed
18.
go back to reference Fries J, Spitz P, Kraines R, Holman H: Measurement of patient outcome in arthritis. Arthritis Rheumatism. 1980, 23: 137-45. 10.1002/art.1780230202.CrossRefPubMed Fries J, Spitz P, Kraines R, Holman H: Measurement of patient outcome in arthritis. Arthritis Rheumatism. 1980, 23: 137-45. 10.1002/art.1780230202.CrossRefPubMed
19.
go back to reference EuroQol G: EuroQol - a new facility for the measurement of health-related quality of life. Health Policy. 1990, 16: 199-208.CrossRef EuroQol G: EuroQol - a new facility for the measurement of health-related quality of life. Health Policy. 1990, 16: 199-208.CrossRef
20.
go back to reference Gardenas J: Echelles et outils d'évaluation en Médecine GénéraleLe Généraliste. 2002, 2187- Gardenas J: Echelles et outils d'évaluation en Médecine GénéraleLe Généraliste. 2002, 2187-
22.
25.
go back to reference Perneger T, Combescure C, Courvoisier S: General population reference values for the French version of the EuroQol EQ-5D health utility instrument.V. Value in Health. 2010, 13: 631-5. 10.1111/j.1524-4733.2010.00727.x.CrossRefPubMed Perneger T, Combescure C, Courvoisier S: General population reference values for the French version of the EuroQol EQ-5D health utility instrument.V. Value in Health. 2010, 13: 631-5. 10.1111/j.1524-4733.2010.00727.x.CrossRefPubMed
26.
go back to reference Perdriger A, Solano C, Gossec L: Pourquoi les rhumatologues devraient-ils s’intéresser à la sexualité des patients souffrant d’une polyarthrite rhumatoïde ?. Revue du Rhumatisme. 2010, 77: 415-7. 10.1016/j.rhum.2010.06.003.CrossRef Perdriger A, Solano C, Gossec L: Pourquoi les rhumatologues devraient-ils s’intéresser à la sexualité des patients souffrant d’une polyarthrite rhumatoïde ?. Revue du Rhumatisme. 2010, 77: 415-7. 10.1016/j.rhum.2010.06.003.CrossRef
Metadata
Title
Rheumatoid arthritis and sexuality: A patient survey in France
Authors
Gisela Kobelt
Brigitte Texier-Richard
Sylvain Mimoun
Anne-Sophie Woronoff
David-Romain Bertholon
Aleth Perdriger
Yves Maugars
Bernard Combe
Publication date
01-12-2012
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2012
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/1471-2474-13-170

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