Skip to main content
Top
Published in: BMC Public Health 1/2003

Open Access 01-12-2003 | Study protocol

Epidemiology of cardiovascular risk factors in Greece: aims, design and baseline characteristics of the ATTICA study

Authors: Christos Pitsavos, Demosthenes B Panagiotakos, Christina Chrysohoou, Christodoulos Stefanadis

Published in: BMC Public Health | Issue 1/2003

Login to get access

Abstract

Background

In an attempt to evaluate the levels of several cardiovascular risk factors in Greece we conducted a population-based health and nutrition survey, the "ATTICA study". In this work we present the design and the methodology of the study, as well as the status of various baseline characteristics of the participants.

Methods

From May 2001 to December 2002 we randomly enrolled 1514 adult men and 1528 adult women, stratified by age – gender (census 2000), from the greater area of Athens. More than 300 demographic, lifestyle, behavioral, dietary, clinical and biochemical variables have been recorded.

Results

Regarding the frequency of the classical cardiovascular risk factors we observed that 51% of men and 39% of women reported smokers (p < 0.05), 37% of men and 25% of women were defined as hypertensives (p < 0.05), 46% of men and 40% of women had total serum cholesterol levels above 200 mg/dl (p < 0.05) and 8% of men and 6% of women had history of diabetes mellitus. Moreover, 20% of men and 15% of women were obese (p < 0.05), while men were more physically active as compared to women (42% vs. 39%, p < 0.05). 19% of men and 38% of women had mild to severe depressive symptoms (p < 0.01). Finally, 72 men (5%) and 45 (3%) women reported history of coronary heart disease at entry evaluation.

Conclusions

The prevalence of the common cardiovascular risk factors in our population seems high. As a consequence a considerable proportion of Greek adults are at "high-risk" for future cardiovascular events.
Literature
1.
go back to reference Kannel WB, McGee DL, Gordon T: A general cardiovascular risk profile: The Framingham Study. Am J Cardiol. 1976, 38: 46-51.CrossRefPubMed Kannel WB, McGee DL, Gordon T: A general cardiovascular risk profile: The Framingham Study. Am J Cardiol. 1976, 38: 46-51.CrossRefPubMed
2.
go back to reference Gotto AM: Interactions of the major risk factors for coronary heart disease. Am J Med. 1986, 80: 48-55.CrossRefPubMed Gotto AM: Interactions of the major risk factors for coronary heart disease. Am J Med. 1986, 80: 48-55.CrossRefPubMed
3.
go back to reference Menotti A, Lanti M, Puddu PE, Kromhout D: Coronary heart disease incidence in northern and southern European populations: a reanalysis of the Seven Countries study for a European coronary risk chart. Heart. 2000, 84: 238-244. 10.1136/heart.84.3.238.CrossRefPubMedPubMedCentral Menotti A, Lanti M, Puddu PE, Kromhout D: Coronary heart disease incidence in northern and southern European populations: a reanalysis of the Seven Countries study for a European coronary risk chart. Heart. 2000, 84: 238-244. 10.1136/heart.84.3.238.CrossRefPubMedPubMedCentral
4.
go back to reference Wood D: Established and emerging cardiovascular risk factors. Am Heart J. 2001, 141: 49-57. 10.1067/mhj.2001.109951.CrossRef Wood D: Established and emerging cardiovascular risk factors. Am Heart J. 2001, 141: 49-57. 10.1067/mhj.2001.109951.CrossRef
5.
go back to reference Haq IU, Ramsay LE, Yeo WW, Jackson PR, Wallis EJ: Is the Framingham risk function valid for northern European populations? A comparison of methods for estimating absolute coronary risk in high-risk men. Heart. 1999, 81: 40-46.CrossRefPubMedPubMedCentral Haq IU, Ramsay LE, Yeo WW, Jackson PR, Wallis EJ: Is the Framingham risk function valid for northern European populations? A comparison of methods for estimating absolute coronary risk in high-risk men. Heart. 1999, 81: 40-46.CrossRefPubMedPubMedCentral
6.
go back to reference Moulopoulos SD, Adamopoulos PN, Diamantopoulos EI, Nanas SN, Anthopoulos LN, Iliadi-Alexandrou M: Coronary heart disease risk factors in a random sample of Athenian adults. The Athens Study. Am J Epidemiol. 1987, 126: 882-892.PubMed Moulopoulos SD, Adamopoulos PN, Diamantopoulos EI, Nanas SN, Anthopoulos LN, Iliadi-Alexandrou M: Coronary heart disease risk factors in a random sample of Athenian adults. The Athens Study. Am J Epidemiol. 1987, 126: 882-892.PubMed
7.
go back to reference Kalandidi A, Tzonou A, Toupadaki N, Lan SJ, Koutis C, Drogari P, Notara V, Hsieh CC, Toutouzas P, Trichopoulos D: A case-control study of coronary heart disease in Athens, Greece. Int J Epidemiol. 1992, 21: 1074-1080.CrossRefPubMed Kalandidi A, Tzonou A, Toupadaki N, Lan SJ, Koutis C, Drogari P, Notara V, Hsieh CC, Toutouzas P, Trichopoulos D: A case-control study of coronary heart disease in Athens, Greece. Int J Epidemiol. 1992, 21: 1074-1080.CrossRefPubMed
8.
go back to reference Panagiotakos DB, Pitsavos C, Chrysohoou C, Stefanadis C, Toutouzas PK: Risk stratification of coronary heart disease through established and emerging lifestyle factors, in a mediterranean population: cardio2000 epidemiological study. J Cardiov Risk. 2001, 6: 329-339. 10.1097/00043798-200112000-00001. Panagiotakos DB, Pitsavos C, Chrysohoou C, Stefanadis C, Toutouzas PK: Risk stratification of coronary heart disease through established and emerging lifestyle factors, in a mediterranean population: cardio2000 epidemiological study. J Cardiov Risk. 2001, 6: 329-339. 10.1097/00043798-200112000-00001.
9.
go back to reference Kalapothaki V, Kalantidi A, Katsouyanni K, Trichopoulou A, Kyriopoulos J, Kremastinou J, Hadjiconstantinou V, Trichopoulos D: The health of the Greek population. Materia Med Greca. 1992, 20: 91-164. Kalapothaki V, Kalantidi A, Katsouyanni K, Trichopoulou A, Kyriopoulos J, Kremastinou J, Hadjiconstantinou V, Trichopoulos D: The health of the Greek population. Materia Med Greca. 1992, 20: 91-164.
10.
go back to reference Trichopoulou A: From Research to Education: The Greek experience. Nutrition. 2000, 16: 528-531. 10.1016/S0899-9007(00)00346-4.CrossRefPubMed Trichopoulou A: From Research to Education: The Greek experience. Nutrition. 2000, 16: 528-531. 10.1016/S0899-9007(00)00346-4.CrossRefPubMed
11.
go back to reference Willett WC, Sacks F, Trichopoulou A, Drescher G, Ferro-Luzzi A, Helsing E, Trichopoulos D: Mediterranean diet pyramid: a cultural model for healthy eating. Am J Clin Nutr. 1995, 6: 1402S-1406S. Willett WC, Sacks F, Trichopoulou A, Drescher G, Ferro-Luzzi A, Helsing E, Trichopoulos D: Mediterranean diet pyramid: a cultural model for healthy eating. Am J Clin Nutr. 1995, 6: 1402S-1406S.
12.
13.
go back to reference Spielberger CD, Jacobs G, Russell R, Crane RS: Assessment of Anger: The State-Trait Anger Scale. In Advances in Personality Assessment. Edited by: Spielberger CD, Butcher JN. 1970, Hillsdale, New Jersey: Lawrence Erlbaum Associates, Inc., Publishers, 161-169. Spielberger CD, Jacobs G, Russell R, Crane RS: Assessment of Anger: The State-Trait Anger Scale. In Advances in Personality Assessment. Edited by: Spielberger CD, Butcher JN. 1970, Hillsdale, New Jersey: Lawrence Erlbaum Associates, Inc., Publishers, 161-169.
14.
go back to reference Stergiou GS, Thomopoulou GC, Skeva II, Mountokalakis TD: Prevalence, awareness, treatment, and control of hypertension in Greece: the Didima study. Am J Hypertens. 1999, 12: 959-965. 10.1016/S0895-7061(99)00136-3.CrossRefPubMed Stergiou GS, Thomopoulou GC, Skeva II, Mountokalakis TD: Prevalence, awareness, treatment, and control of hypertension in Greece: the Didima study. Am J Hypertens. 1999, 12: 959-965. 10.1016/S0895-7061(99)00136-3.CrossRefPubMed
15.
go back to reference Banegas JR, Rodriguez-Artalejo F, Ruilope LM, Graciani A, Luque M, De La Cruz-Troca JJ, Garcia-Robles R, Tamargo J, Rey-Calero J: Hypertension magnitude and management in the elderly population of Spain. J Hypertens. 2002, 20: 2157-2164. 10.1097/00004872-200211000-00014.CrossRefPubMed Banegas JR, Rodriguez-Artalejo F, Ruilope LM, Graciani A, Luque M, De La Cruz-Troca JJ, Garcia-Robles R, Tamargo J, Rey-Calero J: Hypertension magnitude and management in the elderly population of Spain. J Hypertens. 2002, 20: 2157-2164. 10.1097/00004872-200211000-00014.CrossRefPubMed
16.
go back to reference Gasse C, Hense HW, Stieber J, Doring A, Liese AD, Keil U: Assessing hypertension management in the community: trends of prevalence, detection, treatment, and control of hypertension in the MONICA Project, Augsburg 1984–1995. J Hum Hypertens. 2001, 15: 27-36. 10.1038/sj.jhh.1001120.CrossRefPubMed Gasse C, Hense HW, Stieber J, Doring A, Liese AD, Keil U: Assessing hypertension management in the community: trends of prevalence, detection, treatment, and control of hypertension in the MONICA Project, Augsburg 1984–1995. J Hum Hypertens. 2001, 15: 27-36. 10.1038/sj.jhh.1001120.CrossRefPubMed
17.
go back to reference Joffres MR, Ghadirian P, Fodor JG, Petrasovits A, Chockalingam A, Hamet P: Awareness, treatment, and control of hypertension in Canada. Am J Hypertens. 1997, 10: 1097-1102. 10.1016/S0895-7061(97)00224-0.CrossRefPubMed Joffres MR, Ghadirian P, Fodor JG, Petrasovits A, Chockalingam A, Hamet P: Awareness, treatment, and control of hypertension in Canada. Am J Hypertens. 1997, 10: 1097-1102. 10.1016/S0895-7061(97)00224-0.CrossRefPubMed
18.
go back to reference De Backer G, Myny K, De Henauw S, Doyen Z, Van Oyen H, Tafforeau J, Kornitzer M: Prevalence, awareness, treatment and control of arterial hypertension in an elderly population in Belgium. J Hum Hypertens. 1998, 12: 701-706. 10.1038/sj.jhh.1000695.CrossRefPubMed De Backer G, Myny K, De Henauw S, Doyen Z, Van Oyen H, Tafforeau J, Kornitzer M: Prevalence, awareness, treatment and control of arterial hypertension in an elderly population in Belgium. J Hum Hypertens. 1998, 12: 701-706. 10.1038/sj.jhh.1000695.CrossRefPubMed
19.
go back to reference Whelton PK, He J, Appel LJ, Cutler JA, Havas S, Kotchen TA, Roccella EJ, Stout R, Vallbona C, Winston MC, Karimbakas J: The National High Blood Pressure Education Program Coordinating Committee. Primary prevention of hypertension: clinical and public health advisory from The National High Blood Pressure Education Program. JAMA. 2002, 88: 1882-1888.CrossRef Whelton PK, He J, Appel LJ, Cutler JA, Havas S, Kotchen TA, Roccella EJ, Stout R, Vallbona C, Winston MC, Karimbakas J: The National High Blood Pressure Education Program Coordinating Committee. Primary prevention of hypertension: clinical and public health advisory from The National High Blood Pressure Education Program. JAMA. 2002, 88: 1882-1888.CrossRef
20.
go back to reference Dontas A: Recent trends in Cardiovascular disease and risk factors in the Seven Countries Study: Greece. In Lessons for Science from the Seven Countries Study. Edited by: Toshima H, Koga Y, Blackburn H, Keys A. 1994, Tokyo, Japan: Springer-Verlag Pub Dontas A: Recent trends in Cardiovascular disease and risk factors in the Seven Countries Study: Greece. In Lessons for Science from the Seven Countries Study. Edited by: Toshima H, Koga Y, Blackburn H, Keys A. 1994, Tokyo, Japan: Springer-Verlag Pub
21.
go back to reference Third report on Nutrition monitoring in the United States;. Washington DC, USA. Government Printing Office. 1995 Third report on Nutrition monitoring in the United States;. Washington DC, USA. Government Printing Office. 1995
22.
go back to reference European Status Report 2001: A project of the European network for smoking prevention (ENSP);. Brussels, Belgium. 2001 European Status Report 2001: A project of the European network for smoking prevention (ENSP);. Brussels, Belgium. 2001
23.
go back to reference Kuczmarski RJ, Flegal KM, Campbell SM, Johnson CL: Increasing prevalence of overweight among US adults: the National Health and Nutrition Examination Surveys, 1960 to 1991. JAMA. 1994, 272: 205-211. 10.1001/jama.272.3.205.CrossRefPubMed Kuczmarski RJ, Flegal KM, Campbell SM, Johnson CL: Increasing prevalence of overweight among US adults: the National Health and Nutrition Examination Surveys, 1960 to 1991. JAMA. 1994, 272: 205-211. 10.1001/jama.272.3.205.CrossRefPubMed
24.
go back to reference Pearson T, Mensah G, Alexander W, Anderson J, Cannon R, Criqui M, Fadl Y, Fortmann S, Hong Y, Myers G, et al: Markers of inflammation and cardiovascular disease. Application to clinical and public health practice. Circulation. 2003, 107: 499-511. 10.1161/01.CIR.0000052939.59093.45.CrossRefPubMed Pearson T, Mensah G, Alexander W, Anderson J, Cannon R, Criqui M, Fadl Y, Fortmann S, Hong Y, Myers G, et al: Markers of inflammation and cardiovascular disease. Application to clinical and public health practice. Circulation. 2003, 107: 499-511. 10.1161/01.CIR.0000052939.59093.45.CrossRefPubMed
Metadata
Title
Epidemiology of cardiovascular risk factors in Greece: aims, design and baseline characteristics of the ATTICA study
Authors
Christos Pitsavos
Demosthenes B Panagiotakos
Christina Chrysohoou
Christodoulos Stefanadis
Publication date
01-12-2003
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2003
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-3-32

Other articles of this Issue 1/2003

BMC Public Health 1/2003 Go to the issue