Skip to main content
Top
Published in: BMC Public Health 1/2014

Open Access 01-12-2014 | Research article

Coverage, compliance and factors associated with utilization of iron supplementation during pregnancy in eight rural districts of Ethiopia: a cross-sectional study

Authors: Samson Gebremedhin, Aregash Samuel, Girma Mamo, Tibebu Moges, Tsehai Assefa

Published in: BMC Public Health | Issue 1/2014

Login to get access

Abstract

Background

Despite the efforts to reduce iron deficiency during pregnancy, information on the coverage and factors associated with utilization of iron supplements is lacking. The study is intended to assess the coverage, compliance and factors associated with the use of prenatal iron supplements in eight rural districts of Ethiopia.

Methods

The study comprised two independent surveys conducted among pregnant women (n = 414) and women who gave birth in the preceding year of the survey (n = 1573). In both cases, respondents were selected using multistage sampling technique and data were collected via structured questionnaire. Predictors of iron supplement utilization (ranked categories of number of prenatal supplements taken) were identified using ordinal logistic regression. The outputs of the analysis are given using adjusted Odds Ratio (OR) with 95% Confidence Interval (CI).

Results

Among women who gave birth in the preceding year, 35.4% (95% CI: 31.3-39.5) were given/prescribed prenatal iron supplement during the index pregnancy and only 3.5% were supplemented for the recommended 91 or more days. Compared to women who had 4 or more ANC visits, those with 0, 1, 2 and 3 visits had 0.04, 0.33, 0.50 and 0.60 times less odds of iron supplement utilization, respectively. Women lacking comprehensive knowledge of anemia (OR = 0. 75 (95% CI: 0.57-0.97)) and those who weren’t informed about the importance of iron supplementation during the pregnancy (OR = 0. 05 (95% CI: 0.04-0.07)) had significantly lower utilization. On the other hand, in pregnant women the prevalence of anemia was 33.2%. Among pregnant women who were given/prescribed supplements, the average level of compliance was 74.9% and about 25.1% had less than 70% adherence. The leading reported reasons for non-adherence were side-effects (63.3%) and forgetfulness (16.7%).

Conclusion

Promoting early and frequent ANC, enhancing the quality of ANC counseling and promoting the knowledge of women on anemia are essential strategies for improving the utilization of iron supplements.
Appendix
Available only for authorised users
Literature
1.
go back to reference Worldwide prevalence of anemia 1993–2005: WHO global database on anemia. Edited by: Benoist B De, McLean E, Egli I, Cogswell M. 2008, Geneva: WHO, CDC Worldwide prevalence of anemia 1993–2005: WHO global database on anemia. Edited by: Benoist B De, McLean E, Egli I, Cogswell M. 2008, Geneva: WHO, CDC
2.
go back to reference Badham J, Zimmermann MB, Kraemer K: (Ed): The guidebook nutritional anemia. 2007, Basel: Sight and Life Badham J, Zimmermann MB, Kraemer K: (Ed): The guidebook nutritional anemia. 2007, Basel: Sight and Life
3.
go back to reference Allen LH: Anemia and iron deficiency: effects on pregnancy outcome. Am J Clin Nutr. 2000, 71 (suppl): 1280-1284. Allen LH: Anemia and iron deficiency: effects on pregnancy outcome. Am J Clin Nutr. 2000, 71 (suppl): 1280-1284.
4.
go back to reference Khan KS, Wojdyla D, Say L, Gülmezoglu AM, Van Look P: WHO analysis of causes of maternal death: a systematic review. Lancet. 2006, 367: 1066-1074. 10.1016/S0140-6736(06)68397-9.CrossRefPubMed Khan KS, Wojdyla D, Say L, Gülmezoglu AM, Van Look P: WHO analysis of causes of maternal death: a systematic review. Lancet. 2006, 367: 1066-1074. 10.1016/S0140-6736(06)68397-9.CrossRefPubMed
5.
go back to reference Stoltzfus RJ, Mullany L, Black RE: Iron deficiency anemia. comparative quantification of health risks. Edited by: Ezzati M, Lopez AD, Rodgers A, Murray C. 2004, Geneva: WHO Press, Volume 1: 163-209. Stoltzfus RJ, Mullany L, Black RE: Iron deficiency anemia. comparative quantification of health risks. Edited by: Ezzati M, Lopez AD, Rodgers A, Murray C. 2004, Geneva: WHO Press, Volume 1: 163-209.
6.
go back to reference Central Statistical Agency of Ethiopia, Measure DHS: Ethiopia demographic and health survey 2011. 2011, Addis Ababa and Calverton: CSA Ethiopia and MEASURE DHS-ICF Macro Central Statistical Agency of Ethiopia, Measure DHS: Ethiopia demographic and health survey 2011. 2011, Addis Ababa and Calverton: CSA Ethiopia and MEASURE DHS-ICF Macro
7.
go back to reference ORC Macro, Central Statistical Agency of Ethiopia: Ethiopia demographic and health survey 2005. 2006, Central Statistical Agency and ORC Macro: Addis Ababa and Calverton ORC Macro, Central Statistical Agency of Ethiopia: Ethiopia demographic and health survey 2005. 2006, Central Statistical Agency and ORC Macro: Addis Ababa and Calverton
8.
go back to reference Haidar J, Pobocik R: Iron deficiency anemia is not a rare problem among women of reproductive ages in Ethiopia: a community based cross-sectional study. BMC Blood Disord. 2009, 9: 7-10.1186/1471-2326-9-7. doi:10.1186/1471-2326-9-7PubMedPubMedCentral Haidar J, Pobocik R: Iron deficiency anemia is not a rare problem among women of reproductive ages in Ethiopia: a community based cross-sectional study. BMC Blood Disord. 2009, 9: 7-10.1186/1471-2326-9-7. doi:10.1186/1471-2326-9-7PubMedPubMedCentral
9.
go back to reference Haidar J: Prevalence of anemia, deficiencies of iron and folic acid and their determinants in Ethiopian women. J Health Popul Nutr. 2010, 28 (4): 359-368.CrossRefPubMedPubMedCentral Haidar J: Prevalence of anemia, deficiencies of iron and folic acid and their determinants in Ethiopian women. J Health Popul Nutr. 2010, 28 (4): 359-368.CrossRefPubMedPubMedCentral
10.
go back to reference Haidar J, Nekatibeb H, Urga K: Iron deficiency anemia in pregnant and lactating mothers in rural Ethiopia. East Afr Med J. 1999, 76 (11): 618-622.PubMed Haidar J, Nekatibeb H, Urga K: Iron deficiency anemia in pregnant and lactating mothers in rural Ethiopia. East Afr Med J. 1999, 76 (11): 618-622.PubMed
11.
go back to reference WHO: Weekly iron–folic acid supplementation (WIFS) in women of reproductive age: its role in promoting optimal maternal and child health. Position statement. 2009, Geneva: WHO Press WHO: Weekly iron–folic acid supplementation (WIFS) in women of reproductive age: its role in promoting optimal maternal and child health. Position statement. 2009, Geneva: WHO Press
12.
go back to reference Federal Ministry of Health (FMOH) of Ethiopia: National guideline for control and prevention of micronutrient deficiencies. 2004, Addis Ababa: FMOH Federal Ministry of Health (FMOH) of Ethiopia: National guideline for control and prevention of micronutrient deficiencies. 2004, Addis Ababa: FMOH
13.
go back to reference International Food Policy Research Institute: Framework document for a national nutrition strategy for Ethiopia. 2005, Addis Ababa: IFPRI International Food Policy Research Institute: Framework document for a national nutrition strategy for Ethiopia. 2005, Addis Ababa: IFPRI
14.
go back to reference Campbell MJ, Julious SA, Altman DG: Estimating sample sizes for binary, ordered categorical and continuous outcomes in two group comparisons. BMJ. 1995, 311: 1145-1148. 10.1136/bmj.311.7013.1145.CrossRefPubMedPubMedCentral Campbell MJ, Julious SA, Altman DG: Estimating sample sizes for binary, ordered categorical and continuous outcomes in two group comparisons. BMJ. 1995, 311: 1145-1148. 10.1136/bmj.311.7013.1145.CrossRefPubMedPubMedCentral
15.
go back to reference Lutsey PL, Dawe D, Villate E, Valencia S, Lopez O: Iron supplementation compliance among pregnant women in Bicol, Philippines. Public Health Nutr. 2007, 11 (1): 76-82. doi:10.1017/S1368980007000237PubMed Lutsey PL, Dawe D, Villate E, Valencia S, Lopez O: Iron supplementation compliance among pregnant women in Bicol, Philippines. Public Health Nutr. 2007, 11 (1): 76-82. doi:10.1017/S1368980007000237PubMed
17.
go back to reference Schultink W, Van der Ree M, Matulessi P, Gross R: Low compliance with an iron-supplementation program: a study among pregnant women in Jakarta, Indonesia. Am J Clin Nutr. 1993, 57: 135-139.PubMed Schultink W, Van der Ree M, Matulessi P, Gross R: Low compliance with an iron-supplementation program: a study among pregnant women in Jakarta, Indonesia. Am J Clin Nutr. 1993, 57: 135-139.PubMed
18.
go back to reference Ibrahim ZM, El-hamid SA, Mikhail H, Khattab MS: Assessment of adherence to iron and folic acid Ssupplementation and prevalence of anemia in pregnant women. Med J Cairo Univ. 2011, 79 (2): 115-121. Ibrahim ZM, El-hamid SA, Mikhail H, Khattab MS: Assessment of adherence to iron and folic acid Ssupplementation and prevalence of anemia in pregnant women. Med J Cairo Univ. 2011, 79 (2): 115-121.
19.
go back to reference Ogundipe O, Hoyo1 C, Ostbye T, Oneko O, Manongi R, Lie RT, Daltveit AK: Iron supplementation among 21,889 pregnant women in Northern Tanzania: a cross-sectional hospital-based study. BMC Public Health. 2012, 12: 481-10.1186/1471-2458-12-481.CrossRefPubMedPubMedCentral Ogundipe O, Hoyo1 C, Ostbye T, Oneko O, Manongi R, Lie RT, Daltveit AK: Iron supplementation among 21,889 pregnant women in Northern Tanzania: a cross-sectional hospital-based study. BMC Public Health. 2012, 12: 481-10.1186/1471-2458-12-481.CrossRefPubMedPubMedCentral
20.
go back to reference Lacerte P, Pradipasen M, Temcharoen P, Imamee N, Vorapongsathorn T: Determinants of adherence to Iron/Folate supplementation during pregnancy in two provinces in Cambodia. Asia Pac J Public Health. 2011, 23 (3): 315-323. 10.1177/1010539511403133.CrossRefPubMed Lacerte P, Pradipasen M, Temcharoen P, Imamee N, Vorapongsathorn T: Determinants of adherence to Iron/Folate supplementation during pregnancy in two provinces in Cambodia. Asia Pac J Public Health. 2011, 23 (3): 315-323. 10.1177/1010539511403133.CrossRefPubMed
21.
go back to reference Knudsen VK, Hansen HS, Ovesen L, Mikkelsen TB, Olsen SF: Iron supplement use among Danish pregnant women. Public Health Nutr. 2007, 10 (10): 1104-1110. doi:10.1017/S136898000769956XCrossRefPubMed Knudsen VK, Hansen HS, Ovesen L, Mikkelsen TB, Olsen SF: Iron supplement use among Danish pregnant women. Public Health Nutr. 2007, 10 (10): 1104-1110. doi:10.1017/S136898000769956XCrossRefPubMed
22.
go back to reference Habib F, Alabdin EH, Alenazy M, Nooh R: Compliance to iron supplementation during pregnancy. J Obstet Gynecol. 2009, 29 (6): 487-492. 10.1080/01443610902984961.CrossRef Habib F, Alabdin EH, Alenazy M, Nooh R: Compliance to iron supplementation during pregnancy. J Obstet Gynecol. 2009, 29 (6): 487-492. 10.1080/01443610902984961.CrossRef
23.
go back to reference Jasti S, Siega-Riz AM, Cogswell ME, Hartzema AG, Bentley ME: Pill count adherence to prenatal multivitamin/mineral supplement use among low-income women. J Nutr. 2005, 135: 1093-1101.PubMed Jasti S, Siega-Riz AM, Cogswell ME, Hartzema AG, Bentley ME: Pill count adherence to prenatal multivitamin/mineral supplement use among low-income women. J Nutr. 2005, 135: 1093-1101.PubMed
24.
go back to reference World Health Organization (WHO: Iron deficiency anemia: assessment, prevention, and control. 2001, Geneva: WHO press World Health Organization (WHO: Iron deficiency anemia: assessment, prevention, and control. 2001, Geneva: WHO press
25.
go back to reference Wulff M, Ekstrom E: Iron supplementation during pregnancy in Sweden: to what extent is the national recommendation followed?. Acta Obstet Gynecol Scand. 2003, 82 (7): 628-635. 10.1034/j.1600-0412.2003.00186.x.CrossRefPubMed Wulff M, Ekstrom E: Iron supplementation during pregnancy in Sweden: to what extent is the national recommendation followed?. Acta Obstet Gynecol Scand. 2003, 82 (7): 628-635. 10.1034/j.1600-0412.2003.00186.x.CrossRefPubMed
26.
go back to reference Seck BC, Jackson RT: Determinants of compliance with iron supplementation among pregnant women in Senegal. Public Health Nutr. 2007, 11 (6): 596-605. doi:10.1017/S1368980007000924PubMed Seck BC, Jackson RT: Determinants of compliance with iron supplementation among pregnant women in Senegal. Public Health Nutr. 2007, 11 (6): 596-605. doi:10.1017/S1368980007000924PubMed
27.
go back to reference Bilimale A, Anjum J, Sangolli HN, Mallapur M, Nehru J: Improving adherence to oral iron supplementation during pregnancy. AMJ. 2010, 3 (5): 281-290.CrossRef Bilimale A, Anjum J, Sangolli HN, Mallapur M, Nehru J: Improving adherence to oral iron supplementation during pregnancy. AMJ. 2010, 3 (5): 281-290.CrossRef
28.
go back to reference Hyder SMZ, Persson L, Chowdhury AMR, Ekstrom EC: Do side-effects reduce compliance to iron supplementation? A study of daily- and weekly- dose regimens in pregnancy. J Health Popul Nutr. 2002, 20 (2): 175-179.PubMed Hyder SMZ, Persson L, Chowdhury AMR, Ekstrom EC: Do side-effects reduce compliance to iron supplementation? A study of daily- and weekly- dose regimens in pregnancy. J Health Popul Nutr. 2002, 20 (2): 175-179.PubMed
29.
go back to reference Aikawal R, Jimba M, Nguen KC, Zhao Y, Binns CW, Lee MK: Why do adult women in Vietnam take iron tablets?. BMC Public Health. 2006, 6: 144-10.1186/1471-2458-6-144. doi:10.1186/1471-2458-6-144CrossRef Aikawal R, Jimba M, Nguen KC, Zhao Y, Binns CW, Lee MK: Why do adult women in Vietnam take iron tablets?. BMC Public Health. 2006, 6: 144-10.1186/1471-2458-6-144. doi:10.1186/1471-2458-6-144CrossRef
30.
go back to reference Galloway R, Mcguire J: Determinants of compliance with iron supplementation: Supplies, side-effects or psychology?. Soc Sci Med. 1994, 39 (3): 381-390. 10.1016/0277-9536(94)90135-X.CrossRefPubMed Galloway R, Mcguire J: Determinants of compliance with iron supplementation: Supplies, side-effects or psychology?. Soc Sci Med. 1994, 39 (3): 381-390. 10.1016/0277-9536(94)90135-X.CrossRefPubMed
Metadata
Title
Coverage, compliance and factors associated with utilization of iron supplementation during pregnancy in eight rural districts of Ethiopia: a cross-sectional study
Authors
Samson Gebremedhin
Aregash Samuel
Girma Mamo
Tibebu Moges
Tsehai Assefa
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2014
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-14-607

Other articles of this Issue 1/2014

BMC Public Health 1/2014 Go to the issue