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BMC Public Health
Published in: BMC Public Health 1/2013

Open Access 01-12-2013 | Research article

A case-control study of physical activity patterns and risk of non-fatal myocardial infarction

Authors: Jian Gong, Hannia Campos, Joseph Mark A Fiecas, Stephen T McGarvey, Robert Goldberg, Caroline Richardson, Ana Baylin

Published in: BMC Public Health | Issue 1/2013

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Abstract

Background

The interactive effects of different types of physical activity on cardiovascular disease (CVD) risk have not been fully considered in previous studies. We aimed to identify physical activity patterns that take into account combinations of physical activities and examine the association between derived physical activity patterns and risk of acute myocardial infarction (AMI).

Methods

We examined the relationship between physical activity patterns, identified by principal component analysis (PCA), and AMI risk in a case-control study of myocardial infarction in Costa Rica (N=4172), 1994-2004. The component scores derived from PCA and total METS were used in natural cubic spline models to assess the association between physical activity and AMI risk.

Results

Four physical activity patterns were retained from PCA that were characterized as the rest/sleep, agricultural job, light indoor activity, and manual labor job patterns. The light indoor activity and rest/sleep patterns showed an inverse linear relation (P for linearity=0.001) and a U-shaped association (P for non-linearity=0.03) with AMI risk, respectively. There was an inverse association between total activity-related energy expenditure and AMI risk but it reached a plateau at high levels of physical activity (P for non-linearity=0.01).

Conclusions

These data suggest that a light indoor activity pattern is associated with reduced AMI risk. PCA provides a new approach to investigate the relationship between physical activity and CVD risk.
Appendix
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Metadata
Title
A case-control study of physical activity patterns and risk of non-fatal myocardial infarction
Authors
Jian Gong
Hannia Campos
Joseph Mark A Fiecas
Stephen T McGarvey
Robert Goldberg
Caroline Richardson
Ana Baylin
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2013
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-13-122

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