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Published in: BMC Public Health 1/2010

Open Access 01-12-2010 | Research article

Pattern of fractures across pediatric age groups: analysis of individual and lifestyle factors

Authors: Giuliana Valerio, Francesca Gallè, Caterina Mancusi, Valeria Di Onofrio, Marianna Colapietro, Pasquale Guida, Giorgio Liguori

Published in: BMC Public Health | Issue 1/2010

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Abstract

Background

Knowledge of the epidemiology of children's fractures is essential to develop preventive strategies. The aim of this study was to analyze the individual/lifestyle determinants of fractures across pediatric age groups.

Methods

A cross-sectional study was performed in the first six months of 2008 through questionnaire on a sample of children from an outpatient clinic for pediatric fractures. Differences in gender, anatomic site, circumstances and location of fracture occurrence, behavioural lifestyle, and calcium intake were investigated among three different age classes (pre-school children, school children, and adolescents).

Results

The sample consisted of 382 subjects (2-14 years of age) sustaining a fracture after low or moderate trauma. Males were at a higher risk of fractures than females; greater than two-thirds of injuries occurred after low-energy trauma and the upper limb was more frequently involved. With increasing age, the male/female ratio and time spent in sports participation increased (p < 0.001), while calcium intake and time spent in sedentary behaviors decreased (p < 0.001 and < 0.003, respectively). Gender discordance existed in pre-school children with respect to the anatomic location, and in school children and adolescents with respect to the dynamics. In the adolescent group, males were more physically active and also more sedentary than females. Fractures most frequently occurred in homes (41.6%), followed by playgrounds and footpaths (26.2%), sports facilities (18.3%), and educational facilities (13.9%), with gender differences existing only in adolescence. Twenty-three percent of the subjects sustained one or more fractures in the past. The percentage of recurrent fractures increased with age (p = 0.001), with a similar trend in both genders.

Conclusions

Gender differences were shown in the prevalence of injuries, characteristics, and circumstances across ages. These differences may be explained by the related changes in behaviors, together with attending different places. Individual and lifestyle factors can in part explain the variability in the occurrence of fractures and can also address targeted preventive strategies.
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Literature
1.
go back to reference Landin LA: Fracture patterns in children. Analysis of 8,682 fractures with special reference to incidence, etiology and secular changes in a Swedish urban population 1950-1979. Acta Orthop Scand Suppl. 1983, 202: 1-109.CrossRefPubMed Landin LA: Fracture patterns in children. Analysis of 8,682 fractures with special reference to incidence, etiology and secular changes in a Swedish urban population 1950-1979. Acta Orthop Scand Suppl. 1983, 202: 1-109.CrossRefPubMed
2.
go back to reference Jones IE, Williams SM, Dow N, Goulding A: How many children remain fracture-free during growth? a longitudinal study of children and adolescents participating in the Dunedin Multidisciplinary Health and Development Study. Osteoporos Int. 2002, 13: 990-995. 10.1007/s001980200137.CrossRefPubMed Jones IE, Williams SM, Dow N, Goulding A: How many children remain fracture-free during growth? a longitudinal study of children and adolescents participating in the Dunedin Multidisciplinary Health and Development Study. Osteoporos Int. 2002, 13: 990-995. 10.1007/s001980200137.CrossRefPubMed
3.
go back to reference Cooper C, Dennison EM, Leufkens HG, Bishop N, van Staa TP: Epidemiology of childhood fractures in Britain: a study using the general practice research database. J Bone Miner Res. 2004, 19: 1976-1981. 10.1359/jbmr.040902.CrossRefPubMed Cooper C, Dennison EM, Leufkens HG, Bishop N, van Staa TP: Epidemiology of childhood fractures in Britain: a study using the general practice research database. J Bone Miner Res. 2004, 19: 1976-1981. 10.1359/jbmr.040902.CrossRefPubMed
4.
go back to reference Donaldson LJ, Reckless IP, Mindell JS, Shelton NJ: The epidemiology of fractures in England. J Epidemiol Community Health. 2008, 62: 174-180. 10.1136/jech.2006.056622.CrossRefPubMed Donaldson LJ, Reckless IP, Mindell JS, Shelton NJ: The epidemiology of fractures in England. J Epidemiol Community Health. 2008, 62: 174-180. 10.1136/jech.2006.056622.CrossRefPubMed
5.
go back to reference Khosla S, Melton LJ, Dekutoski MB, Achenbach SJ, Oberg AL, Riggs BL: Incidence of Childhood Distal Forearm Fractures Over 30 Years: A Population-Based Study. JAMA. 2003, 290: 1479-1485. 10.1001/jama.290.11.1479.CrossRefPubMed Khosla S, Melton LJ, Dekutoski MB, Achenbach SJ, Oberg AL, Riggs BL: Incidence of Childhood Distal Forearm Fractures Over 30 Years: A Population-Based Study. JAMA. 2003, 290: 1479-1485. 10.1001/jama.290.11.1479.CrossRefPubMed
6.
go back to reference Ma D, Jones G: Television, computer, and video viewing; physical activity; and upper limb fracture risk in children: a population-based case control study. J Bone Miner Res. 2003, 18: 1970-1977. 10.1359/jbmr.2003.18.11.1970.CrossRefPubMed Ma D, Jones G: Television, computer, and video viewing; physical activity; and upper limb fracture risk in children: a population-based case control study. J Bone Miner Res. 2003, 18: 1970-1977. 10.1359/jbmr.2003.18.11.1970.CrossRefPubMed
7.
go back to reference Goulding A, Rockell JE, Black RE, Grant AM, Jones IE, Williams SM: Children who avoid drinking cow's milk are at increased risk for prepubertal bone fractures. Am Diet Assoc. 2004, 104: 250-253. 10.1016/j.jada.2003.11.008.CrossRef Goulding A, Rockell JE, Black RE, Grant AM, Jones IE, Williams SM: Children who avoid drinking cow's milk are at increased risk for prepubertal bone fractures. Am Diet Assoc. 2004, 104: 250-253. 10.1016/j.jada.2003.11.008.CrossRef
8.
go back to reference Hallal PC, Siqueira FV, Menezes AM, Araújo CL, Norris SA, Victora CG: The role of early life variables on the risk of fractures from birth to early adolescence: a prospective birth cohort study. Osteoporos Int. 2009, 20: 1873-1879. 10.1007/s00198-009-0889-y.CrossRefPubMedPubMedCentral Hallal PC, Siqueira FV, Menezes AM, Araújo CL, Norris SA, Victora CG: The role of early life variables on the risk of fractures from birth to early adolescence: a prospective birth cohort study. Osteoporos Int. 2009, 20: 1873-1879. 10.1007/s00198-009-0889-y.CrossRefPubMedPubMedCentral
9.
go back to reference Manias K, McCabe D, Bishop N: Fractures and recurrent fractures in children; varying effects of environmental factors as well as bone size and mass. Bone. 2006, 39: 652-657. 10.1016/j.bone.2006.03.018.CrossRefPubMed Manias K, McCabe D, Bishop N: Fractures and recurrent fractures in children; varying effects of environmental factors as well as bone size and mass. Bone. 2006, 39: 652-657. 10.1016/j.bone.2006.03.018.CrossRefPubMed
10.
go back to reference Goulding A: Risk factors for fractures in normally active children and adolescents. Med Sport Sci. 2007, 51: 102-120. full_text.CrossRefPubMed Goulding A: Risk factors for fractures in normally active children and adolescents. Med Sport Sci. 2007, 51: 102-120. full_text.CrossRefPubMed
11.
go back to reference Loder RT, Warschausky S, Schwartz EM, Hensinger RN, Greenfield ML: The psychosocial characteristics of children with fractures. J Pediatr Orthop. 1995, 15: 41-46.CrossRefPubMed Loder RT, Warschausky S, Schwartz EM, Hensinger RN, Greenfield ML: The psychosocial characteristics of children with fractures. J Pediatr Orthop. 1995, 15: 41-46.CrossRefPubMed
12.
go back to reference Goulding A, Jones IE, Williams SM, Grant AM, Taylor RW, Manning PJ, Langley J: First fracture is associated with increased risk of new fractures during growth. J Pediatr. 2005, 146: 286-288. 10.1016/j.jpeds.2004.09.029.CrossRefPubMed Goulding A, Jones IE, Williams SM, Grant AM, Taylor RW, Manning PJ, Langley J: First fracture is associated with increased risk of new fractures during growth. J Pediatr. 2005, 146: 286-288. 10.1016/j.jpeds.2004.09.029.CrossRefPubMed
13.
go back to reference Yeh FJ, Grant AM, Williams SM, Goulding A: Children who experience their first fracture at a young age have high rates of fracture. Osteoporos Int. 2006, 17: 267-272. 10.1007/s00198-005-2009-y.CrossRefPubMed Yeh FJ, Grant AM, Williams SM, Goulding A: Children who experience their first fracture at a young age have high rates of fracture. Osteoporos Int. 2006, 17: 267-272. 10.1007/s00198-005-2009-y.CrossRefPubMed
14.
go back to reference Kuczmarski RJ, Ogden CL, Guo SS, Grummer-Strawn LM, Flegal KM, Mei Z, Wei R, Curtin LR, Roche AF, Johnson CL: 2000 CDC Growth Charts for the United States: methods and development. Vital Health Stat 11. 2002, 246: 1-190.PubMed Kuczmarski RJ, Ogden CL, Guo SS, Grummer-Strawn LM, Flegal KM, Mei Z, Wei R, Curtin LR, Roche AF, Johnson CL: 2000 CDC Growth Charts for the United States: methods and development. Vital Health Stat 11. 2002, 246: 1-190.PubMed
15.
go back to reference Clark EM, Ness AR, Tobias JH: Bone fragility contributes to the risk of fracture in children, even after moderate and severe trauma. J Bone Miner Res. 2008, 23: 173-179. 10.1359/jbmr.071010.CrossRefPubMedPubMedCentral Clark EM, Ness AR, Tobias JH: Bone fragility contributes to the risk of fracture in children, even after moderate and severe trauma. J Bone Miner Res. 2008, 23: 173-179. 10.1359/jbmr.071010.CrossRefPubMedPubMedCentral
16.
go back to reference Hansoti B, Beattie T: Can the height of fall predict long bone fracture in children under 24 months?. Eur J Emerg Med. 2005, 12: 285-286. 10.1097/00063110-200512000-00008.CrossRefPubMed Hansoti B, Beattie T: Can the height of fall predict long bone fracture in children under 24 months?. Eur J Emerg Med. 2005, 12: 285-286. 10.1097/00063110-200512000-00008.CrossRefPubMed
17.
go back to reference Chalmers DJ, Marshall SW, Langley JD, Evans MJ, Brunton CR, Kelly A-M, Pickering AF: Height and surfacing as risk factors for injury in falls from playground equipment: a case-control study. Injury Prevention. 1996, 2: 98-104. 10.1136/ip.2.2.98.CrossRefPubMedPubMedCentral Chalmers DJ, Marshall SW, Langley JD, Evans MJ, Brunton CR, Kelly A-M, Pickering AF: Height and surfacing as risk factors for injury in falls from playground equipment: a case-control study. Injury Prevention. 1996, 2: 98-104. 10.1136/ip.2.2.98.CrossRefPubMedPubMedCentral
18.
go back to reference Esposito-del Puente A, del Puente A, Scalfi L, Covino A, Marra M, Contaldo F: Calcium intake in a childhood population showing high prevalence of obesity. Int J Obes Relat Metab Disord. 1997, 21 (Suppl 84): Esposito-del Puente A, del Puente A, Scalfi L, Covino A, Marra M, Contaldo F: Calcium intake in a childhood population showing high prevalence of obesity. Int J Obes Relat Metab Disord. 1997, 21 (Suppl 84):
19.
go back to reference Società Italiana di Nutrizione Umana: LARN. Livelli di assunzione raccomandati di energia e nutrienti per la popolazione italiana. 1996, Milan: EDRA Società Italiana di Nutrizione Umana: LARN. Livelli di assunzione raccomandati di energia e nutrienti per la popolazione italiana. 1996, Milan: EDRA
20.
go back to reference Jones G: Growth, children, and fractures. Curr Osteoporos Rep. 2004, 2: 75-78. 10.1007/s11914-004-0014-2.CrossRefPubMed Jones G: Growth, children, and fractures. Curr Osteoporos Rep. 2004, 2: 75-78. 10.1007/s11914-004-0014-2.CrossRefPubMed
21.
go back to reference Rennie L, Court-Brown CM, Mok JY, Beattie TF: The epidemiology of fractures in children. Injury. 2007, 38: 913-922. 10.1016/j.injury.2007.01.036.CrossRefPubMed Rennie L, Court-Brown CM, Mok JY, Beattie TF: The epidemiology of fractures in children. Injury. 2007, 38: 913-922. 10.1016/j.injury.2007.01.036.CrossRefPubMed
22.
go back to reference MacInnes K, Stone DH: Stages of development and injury: an epidemiological survey of young children presenting to an emergency department. BMC Public Health. 2008, 8: 120-10.1186/1471-2458-8-120.CrossRefPubMedPubMedCentral MacInnes K, Stone DH: Stages of development and injury: an epidemiological survey of young children presenting to an emergency department. BMC Public Health. 2008, 8: 120-10.1186/1471-2458-8-120.CrossRefPubMedPubMedCentral
23.
go back to reference Rockwood CA, Wilkins KE: Fractures in children. 2006, Philadelphia: Lippincott Williams and Wilkins Rockwood CA, Wilkins KE: Fractures in children. 2006, Philadelphia: Lippincott Williams and Wilkins
24.
go back to reference Brinker MR, O'Connor DP: The incidence of fractures and dislocations referred for orthopaedic services in a capitated population. J Bone Joint Surg Am. 2004, 86: 290-297.PubMed Brinker MR, O'Connor DP: The incidence of fractures and dislocations referred for orthopaedic services in a capitated population. J Bone Joint Surg Am. 2004, 86: 290-297.PubMed
25.
go back to reference Bailey DA, Wedge JH, McCulloch RG, Martin AD, Bernhardson SC: Epidemiology of fractures of the distal end of the radius in children as associated with growth. J Bone Joint Surg Am. 1989, 71: 1225-1231.PubMed Bailey DA, Wedge JH, McCulloch RG, Martin AD, Bernhardson SC: Epidemiology of fractures of the distal end of the radius in children as associated with growth. J Bone Joint Surg Am. 1989, 71: 1225-1231.PubMed
26.
go back to reference Castellino N, Bellone S, Rapa A, Vercellotti A, Binotti M, Petri A, Bona G: Puberty onset in Northern Italy: a random sample of 3597 Italian children. J Endocrinol Invest. 2005, 28: 589-594.CrossRefPubMed Castellino N, Bellone S, Rapa A, Vercellotti A, Binotti M, Petri A, Bona G: Puberty onset in Northern Italy: a random sample of 3597 Italian children. J Endocrinol Invest. 2005, 28: 589-594.CrossRefPubMed
27.
go back to reference Cheng JC, Shen WY: Limb fracture pattern in different pediatric age groups: a study of 3,350 children. J Orthop Trauma. 1993, 7: 15-22. 10.1097/00005131-199302000-00004.CrossRefPubMed Cheng JC, Shen WY: Limb fracture pattern in different pediatric age groups: a study of 3,350 children. J Orthop Trauma. 1993, 7: 15-22. 10.1097/00005131-199302000-00004.CrossRefPubMed
28.
go back to reference Cheng JC, Ng BK, Ying SY, Lam PK: A 10-year study of the changes in the pattern and treatment of 6,493 fractures. J Pediatr Orthop. 1999, 19: 344-350. 10.1097/00004694-199905000-00011.PubMed Cheng JC, Ng BK, Ying SY, Lam PK: A 10-year study of the changes in the pattern and treatment of 6,493 fractures. J Pediatr Orthop. 1999, 19: 344-350. 10.1097/00004694-199905000-00011.PubMed
29.
go back to reference Ramsay LJ, Moreton G, Gorman DR, Blake E, Goh D, Elton RA, Beattie TF: Unintentional home injury in preschool-aged children: looking for the key--an exploration of the inter-relationship and relative importance of potential risk factors. Public Health. 2003, 117: 404-411. 10.1016/S0033-3506(03)00072-6.CrossRefPubMed Ramsay LJ, Moreton G, Gorman DR, Blake E, Goh D, Elton RA, Beattie TF: Unintentional home injury in preschool-aged children: looking for the key--an exploration of the inter-relationship and relative importance of potential risk factors. Public Health. 2003, 117: 404-411. 10.1016/S0033-3506(03)00072-6.CrossRefPubMed
30.
go back to reference Lyons RA, Delahunty AM, Heaven M, McCabe M, Allen H, Nash P: Incidence of childhood fractures in affluent and deprived areas: population based study. BMJ. 2000, 320: 1276-1277. 10.1136/bmj.320.7244.1276.CrossRef Lyons RA, Delahunty AM, Heaven M, McCabe M, Allen H, Nash P: Incidence of childhood fractures in affluent and deprived areas: population based study. BMJ. 2000, 320: 1276-1277. 10.1136/bmj.320.7244.1276.CrossRef
31.
go back to reference Stark AD, Bennet GC, Stone DH, Chishti P: Association between childhood fractures and poverty: population based study. BMJ. 2002, 324: 457-10.1136/bmj.324.7335.457.CrossRefPubMedPubMedCentral Stark AD, Bennet GC, Stone DH, Chishti P: Association between childhood fractures and poverty: population based study. BMJ. 2002, 324: 457-10.1136/bmj.324.7335.457.CrossRefPubMedPubMedCentral
32.
go back to reference Williams JM, Currie CE, Wright P, Elton RA, Beattie TF: Socioeconomic status and adolescent injuries. Soc Sci Med. 1997, 44: 1881-1891. 10.1016/S0277-9536(96)00297-3.CrossRefPubMed Williams JM, Currie CE, Wright P, Elton RA, Beattie TF: Socioeconomic status and adolescent injuries. Soc Sci Med. 1997, 44: 1881-1891. 10.1016/S0277-9536(96)00297-3.CrossRefPubMed
33.
go back to reference Wareham K, Johansen A, Stone MD, Saunders J, Jones S, Lyons RA: Seasonal variation in the incidence of wrist and forearm fractures, and its consequences. Injury. 2003, 34: 219-222. 10.1016/S0020-1383(02)00212-7.CrossRefPubMed Wareham K, Johansen A, Stone MD, Saunders J, Jones S, Lyons RA: Seasonal variation in the incidence of wrist and forearm fractures, and its consequences. Injury. 2003, 34: 219-222. 10.1016/S0020-1383(02)00212-7.CrossRefPubMed
34.
go back to reference Tiderius CJ, Landin L, Düppe H: Decreasing incidence of fractures in children: an epidemiological analysis of 1,673 fractures in Malmö, Sweden, 1993-1994. Acta Orthop Scand. 1999, 70: 622-626. 10.3109/17453679908997853.CrossRefPubMed Tiderius CJ, Landin L, Düppe H: Decreasing incidence of fractures in children: an epidemiological analysis of 1,673 fractures in Malmö, Sweden, 1993-1994. Acta Orthop Scand. 1999, 70: 622-626. 10.3109/17453679908997853.CrossRefPubMed
35.
go back to reference Bijur PE, Trumble A, Harel Y, Overpeck MD, Jones D, Scheidt PC: Sports and recreation injuries in US children and adolescents. Arch Pediatr Adolesc Med. 1995, 149: 1009-1016.CrossRefPubMed Bijur PE, Trumble A, Harel Y, Overpeck MD, Jones D, Scheidt PC: Sports and recreation injuries in US children and adolescents. Arch Pediatr Adolesc Med. 1995, 149: 1009-1016.CrossRefPubMed
37.
go back to reference Rivara FP, Bergman AB, LoGerfo JP, Weiss NS: Epidemiology of childhood injuries. II. Sex differences in injury rates. Am J Dis Child. 1982, 136: 502-506.CrossRefPubMed Rivara FP, Bergman AB, LoGerfo JP, Weiss NS: Epidemiology of childhood injuries. II. Sex differences in injury rates. Am J Dis Child. 1982, 136: 502-506.CrossRefPubMed
38.
go back to reference Slemenda CW, Millet JZ, Hui SL, Reister TK, Johnston CC: Role of physical activity in the development of skeletal mass in children. J Bone Miner Res. 1991, 11: 1227-1233. Slemenda CW, Millet JZ, Hui SL, Reister TK, Johnston CC: Role of physical activity in the development of skeletal mass in children. J Bone Miner Res. 1991, 11: 1227-1233.
39.
go back to reference Cooper C, Cawley M, Bhalla A, Egger P, Ring F, Morton L, Barker D: Childhood growth, physical activity, and peak bone mass in women. J Bone Miner Res. 1995, 10: 940-947. 10.1002/jbmr.5650100615.CrossRefPubMed Cooper C, Cawley M, Bhalla A, Egger P, Ring F, Morton L, Barker D: Childhood growth, physical activity, and peak bone mass in women. J Bone Miner Res. 1995, 10: 940-947. 10.1002/jbmr.5650100615.CrossRefPubMed
40.
go back to reference Gofin R, Donchin M, Schulrof B: Motor ability: protective or risk for school injuries?. Accid Anal Prev. 2004, 36: 43-48. 10.1016/S0001-4575(02)00113-6.CrossRefPubMed Gofin R, Donchin M, Schulrof B: Motor ability: protective or risk for school injuries?. Accid Anal Prev. 2004, 36: 43-48. 10.1016/S0001-4575(02)00113-6.CrossRefPubMed
41.
go back to reference Taveras EM, Field AE, Berkey CS, Rifas-Shiman SL, Frazier AL, Colditz GA, Gillman MW: Longitudinal relationship between television viewing and leisure-time physical activity during adolescence. Pediatrics. 2007, 119: 314-319. 10.1542/peds.2005-2974.CrossRef Taveras EM, Field AE, Berkey CS, Rifas-Shiman SL, Frazier AL, Colditz GA, Gillman MW: Longitudinal relationship between television viewing and leisure-time physical activity during adolescence. Pediatrics. 2007, 119: 314-319. 10.1542/peds.2005-2974.CrossRef
42.
go back to reference Ma D, Jones G: Soft drink and milk consumption, physical activity, bone mass, and upper limb fractures in children: a population-based case-control study. Calcif Tissue Int. 2004, 75: 286-291. 10.1007/s00223-004-0274-y.CrossRefPubMed Ma D, Jones G: Soft drink and milk consumption, physical activity, bone mass, and upper limb fractures in children: a population-based case-control study. Calcif Tissue Int. 2004, 75: 286-291. 10.1007/s00223-004-0274-y.CrossRefPubMed
43.
go back to reference Johnson JG, Cohen P, Smailes EM, Kasen S, Brook JS: Television viewing and aggressive behavior during adolescence and adulthood. Science. 2002, 295: 2468-2471. 10.1126/science.1062929.CrossRefPubMed Johnson JG, Cohen P, Smailes EM, Kasen S, Brook JS: Television viewing and aggressive behavior during adolescence and adulthood. Science. 2002, 295: 2468-2471. 10.1126/science.1062929.CrossRefPubMed
44.
go back to reference Pitone ML, Attia MW: Patterns of injury associated with routine childhood falls. Pediatr Emerg Care. 2006, 22: 470-474. 10.1097/01.pec.0000226869.41803.50.CrossRefPubMed Pitone ML, Attia MW: Patterns of injury associated with routine childhood falls. Pediatr Emerg Care. 2006, 22: 470-474. 10.1097/01.pec.0000226869.41803.50.CrossRefPubMed
45.
go back to reference Ferrari SL, Chevalley T, Bonjour JP, Rizzoli R: Childhood fractures are associated with decreased bone mass gain during puberty: an early marker of persistent bone fragility?. J Bone Miner Res. 2006, 21: 501-507. 10.1359/jbmr.051215.CrossRefPubMed Ferrari SL, Chevalley T, Bonjour JP, Rizzoli R: Childhood fractures are associated with decreased bone mass gain during puberty: an early marker of persistent bone fragility?. J Bone Miner Res. 2006, 21: 501-507. 10.1359/jbmr.051215.CrossRefPubMed
46.
go back to reference Goulding A, Jones IE, Taylor RW, Williams SM, Manning PJ: Bone mineral density and body composition in boys with distal forearm fractures: a dual-energy x-ray absorptiometry study. J Pediatr. 2001, 139: 509-515. 10.1067/mpd.2001.116297.CrossRefPubMed Goulding A, Jones IE, Taylor RW, Williams SM, Manning PJ: Bone mineral density and body composition in boys with distal forearm fractures: a dual-energy x-ray absorptiometry study. J Pediatr. 2001, 139: 509-515. 10.1067/mpd.2001.116297.CrossRefPubMed
Metadata
Title
Pattern of fractures across pediatric age groups: analysis of individual and lifestyle factors
Authors
Giuliana Valerio
Francesca Gallè
Caterina Mancusi
Valeria Di Onofrio
Marianna Colapietro
Pasquale Guida
Giorgio Liguori
Publication date
01-12-2010
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2010
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-10-656

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