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Published in: BMC Public Health 1/2010

Open Access 01-12-2010 | Research article

A primary health-care intervention on pre- and postnatal risk factor behavior to prevent childhood allergy. The Prevention of Allergy among Children in Trondheim (PACT) study

Authors: Ola Storrø, Torbjørn Øien, Christian K Dotterud, Jon A Jenssen, Roar Johnsen

Published in: BMC Public Health | Issue 1/2010

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Abstract

Background

This study aimed to evaluate the impact of a primary prevention intervention program on risk behavior for allergic diseases among children up to 2 years of age. The setting was in ordinary pre- and postnatal primary health care in Trondheim, Norway.

Methods

The Prevention of Allergy among Children in Trondheim, Norway (PACT) study invited all pregnant women and parents to children up to 2 years of age in the community to participate in a non-randomized, controlled, multiple life-style intervention study. Interventional topics was increased dietary intake of cod liver oil and oily fish for women during pregnancy and for infants during the first 2 years of life, reduced parental smoking and reduced indoor dampness. A control cohort was established prior to the intervention cohort with "follow up as usual". Questionnaires were completed in pregnancy, 6 weeks after birth and at 1 and 2 years of age. Trends in exposure and behavior are described.

Results

Intake of oily fish and cod liver oil increased statistically significantly among women and infants in the intervention cohort compared to the control cohort. There was a low postnatal smoking prevalence in both cohorts, with a trend towards a decreasing smoking prevalence in the control cohort. There was no change in indoor dampness or in behavior related to non- intervened life-style factors.

Conclusions

The dietary intervention seemed to be successful. The observed reduced smoking behavior could not be attributed to the intervention program, and the latter had no effect on indoor dampness.

Trial registrations

(Current Controlled Trials registration number: ISRCTN28090297)
Appendix
Available only for authorised users
Literature
1.
go back to reference Cook DG, Strachan DP: Health effects of passive smoking-10: Summary of effects of parental smoking on the respiratory health of children and implications for research. Thorax. 1999, 54: 357-366. 10.1136/thx.54.4.357.CrossRefPubMedPubMedCentral Cook DG, Strachan DP: Health effects of passive smoking-10: Summary of effects of parental smoking on the respiratory health of children and implications for research. Thorax. 1999, 54: 357-366. 10.1136/thx.54.4.357.CrossRefPubMedPubMedCentral
2.
go back to reference Diclemente CC, Dolan-Mullen P, Windsor RA: The process of pregnancy smoking cessation: implications for interventions. Tob Control. 2000, 9 (Suppl 3): III16-III21.PubMedPubMedCentral Diclemente CC, Dolan-Mullen P, Windsor RA: The process of pregnancy smoking cessation: implications for interventions. Tob Control. 2000, 9 (Suppl 3): III16-III21.PubMedPubMedCentral
3.
go back to reference Ershoff DH, Quinn VP, Mullen PD: Relapse prevention among women who stop smoking early in pregnancy: a randomized clinical trial of a self-help intervention. Am J Prev Med. 1995, 11: 178-184.PubMed Ershoff DH, Quinn VP, Mullen PD: Relapse prevention among women who stop smoking early in pregnancy: a randomized clinical trial of a self-help intervention. Am J Prev Med. 1995, 11: 178-184.PubMed
4.
go back to reference Ershoff DH, Quinn VP, Boyd NR, Stern J, Gregory M, Wirtschafter D: The Kaiser Permanente prenatal smoking-cessation trial: when more isn't better, what is enough?. Am J Prev Med. 1999, 17: 161-168. 10.1016/S0749-3797(99)00071-9.CrossRefPubMed Ershoff DH, Quinn VP, Boyd NR, Stern J, Gregory M, Wirtschafter D: The Kaiser Permanente prenatal smoking-cessation trial: when more isn't better, what is enough?. Am J Prev Med. 1999, 17: 161-168. 10.1016/S0749-3797(99)00071-9.CrossRefPubMed
5.
go back to reference Nolte H, Backer V, Porsbjerg C: Environmental factors as a cause for the increase in allergic disease. Ann Allergy Asthma Immunol. 2001, 87: 7-11. 10.1016/S1081-1206(10)62333-2.CrossRefPubMed Nolte H, Backer V, Porsbjerg C: Environmental factors as a cause for the increase in allergic disease. Ann Allergy Asthma Immunol. 2001, 87: 7-11. 10.1016/S1081-1206(10)62333-2.CrossRefPubMed
6.
7.
go back to reference Fogarty A, Britton J: The role of diet in the aetiology of asthma. Clin Exp Allergy. 2000, 30: 615-627. 10.1046/j.1365-2222.2000.00766.x.CrossRefPubMed Fogarty A, Britton J: The role of diet in the aetiology of asthma. Clin Exp Allergy. 2000, 30: 615-627. 10.1046/j.1365-2222.2000.00766.x.CrossRefPubMed
8.
go back to reference Hodge L, Salome CM, Peat JK, Haby MM, Xuan W, Woolcock AJ: Consumption of oily fish and childhood asthma risk. Med J Aust. 1996, 164: 137-140.PubMed Hodge L, Salome CM, Peat JK, Haby MM, Xuan W, Woolcock AJ: Consumption of oily fish and childhood asthma risk. Med J Aust. 1996, 164: 137-140.PubMed
9.
go back to reference Woods RK, Thien FC, Abramson MJ: Dietary marine fatty acids (fish oil) for asthma. Cochrane Database Syst Rev. 2000, CD001283- Woods RK, Thien FC, Abramson MJ: Dietary marine fatty acids (fish oil) for asthma. Cochrane Database Syst Rev. 2000, CD001283-
10.
go back to reference Blumer N, Renz H: Consumption of omega3-fatty acids during perinatal life: role in immuno-modulation and allergy prevention. J Perinat Med. 2007, 35 (Suppl 1): S12-S18. 10.1515/JPM.2007.031.PubMed Blumer N, Renz H: Consumption of omega3-fatty acids during perinatal life: role in immuno-modulation and allergy prevention. J Perinat Med. 2007, 35 (Suppl 1): S12-S18. 10.1515/JPM.2007.031.PubMed
11.
go back to reference Dunstan JA, Mori TA, Barden A, Beilin LJ, Taylor AL, Holt PG, et al: Maternal fish oil supplementation in pregnancy reduces interleukin-13 levels in cord blood of infants at high risk of atopy. Clin Exp Allergy. 2003, 33: 442-448. 10.1046/j.1365-2222.2003.01590.x.CrossRefPubMed Dunstan JA, Mori TA, Barden A, Beilin LJ, Taylor AL, Holt PG, et al: Maternal fish oil supplementation in pregnancy reduces interleukin-13 levels in cord blood of infants at high risk of atopy. Clin Exp Allergy. 2003, 33: 442-448. 10.1046/j.1365-2222.2003.01590.x.CrossRefPubMed
12.
go back to reference Dunstan JA, Roper J, Mitoulas L, Hartmann PE, Simmer K, Prescott SL: The effect of supplementation with fish oil during pregnancy on breast milk immunoglobulin A, soluble CD14, cytokine levels and fatty acid composition. Clin Exp Allergy. 2004, 34: 1237-1242. 10.1111/j.1365-2222.2004.02028.x.CrossRefPubMed Dunstan JA, Roper J, Mitoulas L, Hartmann PE, Simmer K, Prescott SL: The effect of supplementation with fish oil during pregnancy on breast milk immunoglobulin A, soluble CD14, cytokine levels and fatty acid composition. Clin Exp Allergy. 2004, 34: 1237-1242. 10.1111/j.1365-2222.2004.02028.x.CrossRefPubMed
13.
go back to reference Hodge L, Salome CM, Hughes JM, Liu-Brennan D, Rimmer J, Allman M, et al: Effect of dietary intake of omega-3 and omega-6 fatty acids on severity of asthma in children. Eur Respir J. 1998, 11: 361-365. 10.1183/09031936.98.11020361.CrossRefPubMed Hodge L, Salome CM, Hughes JM, Liu-Brennan D, Rimmer J, Allman M, et al: Effect of dietary intake of omega-3 and omega-6 fatty acids on severity of asthma in children. Eur Respir J. 1998, 11: 361-365. 10.1183/09031936.98.11020361.CrossRefPubMed
14.
go back to reference Calvani M, Alessandri C, Sopo SM, Panetta V, Pingitore G, Tripodi S, et al: Consumption of fish, butter and margarine during pregnancy and development of allergic sensitizations in the offspring: role of maternal atopy. Pediatr Allergy Immunol. 2006, 17: 94-102. 10.1111/j.1399-3038.2005.00367.x.CrossRefPubMed Calvani M, Alessandri C, Sopo SM, Panetta V, Pingitore G, Tripodi S, et al: Consumption of fish, butter and margarine during pregnancy and development of allergic sensitizations in the offspring: role of maternal atopy. Pediatr Allergy Immunol. 2006, 17: 94-102. 10.1111/j.1399-3038.2005.00367.x.CrossRefPubMed
15.
go back to reference Kull I, Bergstrom A, Lilja G, Pershagen G, Wickman M: Fish consumption during the first year of life and development of allergic diseases during childhood. Allergy. 2006, 61: 1009-1015. 10.1111/j.1398-9995.2006.01115.x.CrossRefPubMed Kull I, Bergstrom A, Lilja G, Pershagen G, Wickman M: Fish consumption during the first year of life and development of allergic diseases during childhood. Allergy. 2006, 61: 1009-1015. 10.1111/j.1398-9995.2006.01115.x.CrossRefPubMed
16.
go back to reference Brunekreef B, Dockery DW, Speizer FE, Ware JH, Spengler JD, Ferris BG: Home dampness and respiratory morbidity in children. Am Rev Respir Dis. 1989, 140: 1363-1367.CrossRefPubMed Brunekreef B, Dockery DW, Speizer FE, Ware JH, Spengler JD, Ferris BG: Home dampness and respiratory morbidity in children. Am Rev Respir Dis. 1989, 140: 1363-1367.CrossRefPubMed
17.
go back to reference Verhoeff AP, van Strien RT, van Wijnen JH, Brunekreef B: Damp housing and childhood respiratory symptoms: the role of sensitization to dust mites and molds. Am J Epidemiol. 1995, 141: 103-110.PubMed Verhoeff AP, van Strien RT, van Wijnen JH, Brunekreef B: Damp housing and childhood respiratory symptoms: the role of sensitization to dust mites and molds. Am J Epidemiol. 1995, 141: 103-110.PubMed
18.
go back to reference Bornehag CG, Blomquist G, Gyntelberg F, Jarvholm B, Malmberg P, Nordvall L, et al: Dampness in buildings and health. Nordic interdisciplinary review of the scientific evidence on associations between exposure to "dampness" in buildings and health effects (NORDDAMP). Indoor Air. 2001, 11: 72-86. 10.1034/j.1600-0668.2001.110202.x.CrossRefPubMed Bornehag CG, Blomquist G, Gyntelberg F, Jarvholm B, Malmberg P, Nordvall L, et al: Dampness in buildings and health. Nordic interdisciplinary review of the scientific evidence on associations between exposure to "dampness" in buildings and health effects (NORDDAMP). Indoor Air. 2001, 11: 72-86. 10.1034/j.1600-0668.2001.110202.x.CrossRefPubMed
19.
go back to reference Billings CG, Howard P: Damp housing and asthma. Monaldi Arch Chest Dis. 1998, 53: 43-49.PubMed Billings CG, Howard P: Damp housing and asthma. Monaldi Arch Chest Dis. 1998, 53: 43-49.PubMed
20.
go back to reference Huss K, Adkinson NF, Eggleston PA, Dawson C, Van Natta ML, Hamilton RG: House dust mite and cockroach exposure are strong risk factors for positive allergy skin test responses in the Childhood Asthma Management Program. J Allergy Clin Immunol. 2001, 107: 48-54. 10.1067/mai.2001.111146.CrossRefPubMed Huss K, Adkinson NF, Eggleston PA, Dawson C, Van Natta ML, Hamilton RG: House dust mite and cockroach exposure are strong risk factors for positive allergy skin test responses in the Childhood Asthma Management Program. J Allergy Clin Immunol. 2001, 107: 48-54. 10.1067/mai.2001.111146.CrossRefPubMed
21.
go back to reference Fisk WJ, Lei-Gomez Q, Mendell MJ: Meta-analyses of the associations of respiratory health effects with dampness and mold in homes. Indoor Air. 2007, 17: 284-296. 10.1111/j.1600-0668.2007.00475.x.CrossRefPubMed Fisk WJ, Lei-Gomez Q, Mendell MJ: Meta-analyses of the associations of respiratory health effects with dampness and mold in homes. Indoor Air. 2007, 17: 284-296. 10.1111/j.1600-0668.2007.00475.x.CrossRefPubMed
22.
go back to reference Hagmolen of Ten Have, van den Berg NJ, van der PJ, van Aalderen WM, Bindels PJ: Residential exposure to mould and dampness is associated with adverse respiratory health. Clin Exp Allergy. 2007, 37: 1827-1832. 10.1111/j.1365-2222.2007.02841.x.CrossRefPubMed Hagmolen of Ten Have, van den Berg NJ, van der PJ, van Aalderen WM, Bindels PJ: Residential exposure to mould and dampness is associated with adverse respiratory health. Clin Exp Allergy. 2007, 37: 1827-1832. 10.1111/j.1365-2222.2007.02841.x.CrossRefPubMed
23.
go back to reference Beech B: Go the extra mile--use the Delphi Technique. J Nurs Manag. 1999, 7: 281-288. 10.1046/j.1365-2834.1999.00125.x.CrossRefPubMed Beech B: Go the extra mile--use the Delphi Technique. J Nurs Manag. 1999, 7: 281-288. 10.1046/j.1365-2834.1999.00125.x.CrossRefPubMed
24.
go back to reference Oien T, Storro O, Johnsen R: Assessing atopic disease in children two to six years old: reliability of a revised questionnaire. Prim Care Respir J. 2008, 17: 164-168. 10.3132/pcrj.2008.00023.CrossRefPubMed Oien T, Storro O, Johnsen R: Assessing atopic disease in children two to six years old: reliability of a revised questionnaire. Prim Care Respir J. 2008, 17: 164-168. 10.3132/pcrj.2008.00023.CrossRefPubMed
25.
go back to reference A clinical practice guideline for treating tobacco use and dependence: A US Public Health Service report. The Tobacco Use and Dependence Clinical Practice Guideline Panel, Staff, and Consortium Representatives. JAMA. 2000, 283: 3244-3254. 10.1001/jama.283.24.3244. A clinical practice guideline for treating tobacco use and dependence: A US Public Health Service report. The Tobacco Use and Dependence Clinical Practice Guideline Panel, Staff, and Consortium Representatives. JAMA. 2000, 283: 3244-3254. 10.1001/jama.283.24.3244.
26.
go back to reference Oien T, Storro O, Jenssen JA, Johnsen R: The impact of a minimal smoking cessation intervention for pregnant women and their partners on perinatal smoking behaviour in primary health care: a real-life controlled study. BMC Public Health. 2008, 8: 325-334. 10.1186/1471-2458-8-325.CrossRefPubMedPubMedCentral Oien T, Storro O, Jenssen JA, Johnsen R: The impact of a minimal smoking cessation intervention for pregnant women and their partners on perinatal smoking behaviour in primary health care: a real-life controlled study. BMC Public Health. 2008, 8: 325-334. 10.1186/1471-2458-8-325.CrossRefPubMedPubMedCentral
27.
go back to reference Thompson SC, Schwankovsky L, Pitts J: Counselling patients to make lifestyle changes: the role of physician self-efficacy, training and beliefs about causes. Fam Pract. 1993, 10: 70-75. 10.1093/fampra/10.1.70.CrossRefPubMed Thompson SC, Schwankovsky L, Pitts J: Counselling patients to make lifestyle changes: the role of physician self-efficacy, training and beliefs about causes. Fam Pract. 1993, 10: 70-75. 10.1093/fampra/10.1.70.CrossRefPubMed
28.
go back to reference Asher MI, Weiland SK: The International Study of Asthma and Allergies in Childhood (ISAAC). ISAAC Steering Committee. Clin Exp Allergy. 1998, 28 (Suppl 5): 52-66. 10.1046/j.1365-2222.1998.028s5052.x.CrossRefPubMed Asher MI, Weiland SK: The International Study of Asthma and Allergies in Childhood (ISAAC). ISAAC Steering Committee. Clin Exp Allergy. 1998, 28 (Suppl 5): 52-66. 10.1046/j.1365-2222.1998.028s5052.x.CrossRefPubMed
29.
go back to reference Bai J, Peat JK, Berry G, Marks GB, Woolcock AJ: Questionnaire items that predict asthma and other respiratory conditions in adults. Chest. 1998, 114: 1343-1348. 10.1378/chest.114.5.1343.CrossRefPubMed Bai J, Peat JK, Berry G, Marks GB, Woolcock AJ: Questionnaire items that predict asthma and other respiratory conditions in adults. Chest. 1998, 114: 1343-1348. 10.1378/chest.114.5.1343.CrossRefPubMed
30.
go back to reference Daly KA, Lindgren B, Giebink GS: Validity of parental report of a child's medical history in otitis media research. Am J Epidemiol. 1994, 139: 1116-1121.PubMed Daly KA, Lindgren B, Giebink GS: Validity of parental report of a child's medical history in otitis media research. Am J Epidemiol. 1994, 139: 1116-1121.PubMed
31.
go back to reference Kilpelainen M, Terho EO, Helenius H, Koskenvuo M: Validation of a new questionnaire on asthma, allergic rhinitis, and conjunctivitis in young adults. Allergy. 2001, 56: 377-384. 10.1034/j.1398-9995.2001.056005377.x.CrossRefPubMed Kilpelainen M, Terho EO, Helenius H, Koskenvuo M: Validation of a new questionnaire on asthma, allergic rhinitis, and conjunctivitis in young adults. Allergy. 2001, 56: 377-384. 10.1034/j.1398-9995.2001.056005377.x.CrossRefPubMed
32.
go back to reference Powell CV, McNamara P, Solis A, Shaw NJ: A parent completed questionnaire to describe the patterns of wheezing and other respiratory symptoms in infants and preschool children. Arch Dis Child. 2002, 87: 376-379. 10.1136/adc.87.5.376.CrossRefPubMedPubMedCentral Powell CV, McNamara P, Solis A, Shaw NJ: A parent completed questionnaire to describe the patterns of wheezing and other respiratory symptoms in infants and preschool children. Arch Dis Child. 2002, 87: 376-379. 10.1136/adc.87.5.376.CrossRefPubMedPubMedCentral
33.
go back to reference Jacobsen BK, Knutsen SF, Knutsen R: The Tromso Heart Study: comparison of information from a short food frequency questionnaire with a dietary history survey. Scand J Soc Med. 1987, 15: 41-47.PubMed Jacobsen BK, Knutsen SF, Knutsen R: The Tromso Heart Study: comparison of information from a short food frequency questionnaire with a dietary history survey. Scand J Soc Med. 1987, 15: 41-47.PubMed
34.
go back to reference Jacobsen BK, Bonaa KH: The reproducibility of dietary data from a self-administered questionnaire. The Tromso Study. Int J Epidemiol. 1990, 19: 349-353. 10.1093/ije/19.2.349.CrossRefPubMed Jacobsen BK, Bonaa KH: The reproducibility of dietary data from a self-administered questionnaire. The Tromso Study. Int J Epidemiol. 1990, 19: 349-353. 10.1093/ije/19.2.349.CrossRefPubMed
35.
go back to reference Asher MI, Weiland SK: The International Study of Asthma and Allergies in Childhood (ISAAC). ISAAC Steering Committee. Clin Exp Allergy. 1998, 28 (Suppl 5): 52-66. 10.1046/j.1365-2222.1998.028s5052.x.CrossRefPubMed Asher MI, Weiland SK: The International Study of Asthma and Allergies in Childhood (ISAAC). ISAAC Steering Committee. Clin Exp Allergy. 1998, 28 (Suppl 5): 52-66. 10.1046/j.1365-2222.1998.028s5052.x.CrossRefPubMed
36.
go back to reference Armstrong R, Waters E, Moore L, Riggs E, Cuervo LG, Lumbiganon P, et al: Improving the reporting of public health intervention research: advancing TREND and CONSORT. J Public Health (Oxf). 2008, 30: 103-109. 10.1093/pubmed/fdm082.CrossRef Armstrong R, Waters E, Moore L, Riggs E, Cuervo LG, Lumbiganon P, et al: Improving the reporting of public health intervention research: advancing TREND and CONSORT. J Public Health (Oxf). 2008, 30: 103-109. 10.1093/pubmed/fdm082.CrossRef
37.
go back to reference Oien T, Storro O, Johnsen R: Do early intake of fish and fish oil protect against eczema and doctor-diagnosed asthma at 2 years of age? A cohort study. J Epidemiol Community Health. 2010, 64: 124-129. 10.1136/jech.2008.084921.CrossRefPubMed Oien T, Storro O, Johnsen R: Do early intake of fish and fish oil protect against eczema and doctor-diagnosed asthma at 2 years of age? A cohort study. J Epidemiol Community Health. 2010, 64: 124-129. 10.1136/jech.2008.084921.CrossRefPubMed
38.
go back to reference Des J, Lyles C, Crepaz N: Improving the reporting quality of nonrandomized evaluations of behavioral and public health interventions: the TREND statement. Am J Public Health. 2004, 94: 361-366. 10.2105/AJPH.94.3.361.CrossRef Des J, Lyles C, Crepaz N: Improving the reporting quality of nonrandomized evaluations of behavioral and public health interventions: the TREND statement. Am J Public Health. 2004, 94: 361-366. 10.2105/AJPH.94.3.361.CrossRef
39.
go back to reference Kaneko M: A methodological inquiry into the evaluation of smoking cessation programmes. Health Educ Res. 1999, 14: 433-441. 10.1093/her/14.3.433.CrossRefPubMed Kaneko M: A methodological inquiry into the evaluation of smoking cessation programmes. Health Educ Res. 1999, 14: 433-441. 10.1093/her/14.3.433.CrossRefPubMed
40.
go back to reference Lannero E, Kull I, Wickman M, Pershagen G, Nordvall SL: Environmental risk factors for allergy and socioeconomic status in a birth cohort (BAMSE). Pediatr Allergy Immunol. 2002, 13: 182-187. 10.1034/j.1399-3038.2002.01055.x.CrossRefPubMed Lannero E, Kull I, Wickman M, Pershagen G, Nordvall SL: Environmental risk factors for allergy and socioeconomic status in a birth cohort (BAMSE). Pediatr Allergy Immunol. 2002, 13: 182-187. 10.1034/j.1399-3038.2002.01055.x.CrossRefPubMed
41.
go back to reference Okamoto K, Ohsuka K, Shiraishi T, Hukazawa E, Wakasugi S, Furuta K: Comparability of epidemiological information between self- and interviewer-administered questionnaires. J Clin Epidemiol. 2002, 55: 505-511. 10.1016/S0895-4356(01)00515-7.CrossRefPubMed Okamoto K, Ohsuka K, Shiraishi T, Hukazawa E, Wakasugi S, Furuta K: Comparability of epidemiological information between self- and interviewer-administered questionnaires. J Clin Epidemiol. 2002, 55: 505-511. 10.1016/S0895-4356(01)00515-7.CrossRefPubMed
42.
go back to reference Post A, Gilljam H, Bremberg S, Galanti MR: Maternal smoking during pregnancy: a comparison between concurrent and retrospective self-reports. Paediatr Perinat Epidemiol. 2008, 22: 155-161. 10.1111/j.1365-3016.2007.00917.x.CrossRefPubMed Post A, Gilljam H, Bremberg S, Galanti MR: Maternal smoking during pregnancy: a comparison between concurrent and retrospective self-reports. Paediatr Perinat Epidemiol. 2008, 22: 155-161. 10.1111/j.1365-3016.2007.00917.x.CrossRefPubMed
43.
go back to reference Edwards PJ, Roberts I, Clarke MJ, DiGuiseppi C, Wentz R, Kwan I, et al: Methods to increase response to postal and electronic questionnaires. Cochrane Database Syst Rev. 2009, MR000008- Edwards PJ, Roberts I, Clarke MJ, DiGuiseppi C, Wentz R, Kwan I, et al: Methods to increase response to postal and electronic questionnaires. Cochrane Database Syst Rev. 2009, MR000008-
44.
go back to reference Bosch-Capblanch X, Abba K, Prictor M, Garner P: Contracts between patients and healthcare practitioners for improving patients' adherence to treatment, prevention and health promotion activities. Cochrane Database Syst Rev. 2007, CD004808- Bosch-Capblanch X, Abba K, Prictor M, Garner P: Contracts between patients and healthcare practitioners for improving patients' adherence to treatment, prevention and health promotion activities. Cochrane Database Syst Rev. 2007, CD004808-
45.
go back to reference McKinstry B, Ashcroft RE, Car J, Freeman GK, Sheikh A: Interventions for improving patients' trust in doctors and groups of doctors. Cochrane Database Syst Rev. 2006, 3: CD004134-PubMed McKinstry B, Ashcroft RE, Car J, Freeman GK, Sheikh A: Interventions for improving patients' trust in doctors and groups of doctors. Cochrane Database Syst Rev. 2006, 3: CD004134-PubMed
Metadata
Title
A primary health-care intervention on pre- and postnatal risk factor behavior to prevent childhood allergy. The Prevention of Allergy among Children in Trondheim (PACT) study
Authors
Ola Storrø
Torbjørn Øien
Christian K Dotterud
Jon A Jenssen
Roar Johnsen
Publication date
01-12-2010
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2010
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-10-443

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