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Published in: BMC Public Health 1/2010

Open Access 01-12-2010 | Research article

Rural to urban migration and changes in cardiovascular risk factors in Tanzania: a prospective cohort study

Authors: Nigel Unwin, Peter James, Dorothy McLarty, Harun Machybia, Peter Nkulila, Bushiri Tamin, Mkay Nguluma, Richard McNally

Published in: BMC Public Health | Issue 1/2010

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Abstract

Background

High levels of rural to urban migration are a feature of most African countries. Our aim was to investigate changes, and their determinants, in cardiovascular risk factors on rural to urban migration in Tanzania.

Methods

Men and women (15 to 59 years) intending to migrate from Morogoro rural region to Dar es Salaam for at least 6 months were identified. Measurements were made at least one week but no more than one month prior to migration, and 1 to 3 monthly after migration. Outcome measures included body mass index, blood pressure, fasting lipids, and self reported physical activity and diet.

Results

One hundred and three men, 106 women, mean age 29 years, were recruited and 132 (63.2%) followed to 12 months. All the figures presented here refer to the difference between baseline and 12 months in these 132 individuals. Vigorous physical activity declined (79.4% to 26.5% in men, 37.8% to 15.6% in women, p < 0.001), and weight increased (2.30 kg men, 2.35 kg women, p < 0.001). Intake of red meat increased, but so did the intake of fresh fruit and vegetables. HDL cholesterol increased in men and women (0.24, 0.25 mmoll-1 respectively, p < 0.001); and in men, not women, total cholesterol increased (0.42 mmoll-1, p = 0.01), and triglycerides fell (0.31 mmoll-1, p = 0.034). Blood pressure appeared to fall in both men and women. For example, in men systolic blood pressure fell by 5.4 mmHg, p = 0.007, and in women by 8.6 mmHg, p = 0.001.

Conclusion

The lower level of physical activity and increasing weight will increase the risk of diabetes and cardiovascular disease. However, changes in diet were mixed, and may have contributed to mixed changes in lipid profiles and a lack of rise in blood pressure. A better understanding of the changes occurring on rural to urban migration is needed to guide preventive measures.
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Literature
1.
go back to reference United Nations Population Division: An overview of urbanization, internal migration, population distribution and development in the world. United Nations expert group meeting on population distribution, urbanisation, internal migration and development. 2008, New York: United Nations United Nations Population Division: An overview of urbanization, internal migration, population distribution and development in the world. United Nations expert group meeting on population distribution, urbanisation, internal migration and development. 2008, New York: United Nations
2.
go back to reference Population Division of the Department of Economic and Social Affairs: World Population Prospects: The 2006 Revision and World Urbanization Prospects. 2009, New York United Nations Population Division of the Department of Economic and Social Affairs: World Population Prospects: The 2006 Revision and World Urbanization Prospects. 2009, New York United Nations
3.
go back to reference Unwin N, Alberti KG: Chronic non-communicable diseases. Annals of Tropical Medicine & Parasitology. 2006, 100 (5-6): 455-464. 10.1179/136485906X97453.CrossRef Unwin N, Alberti KG: Chronic non-communicable diseases. Annals of Tropical Medicine & Parasitology. 2006, 100 (5-6): 455-464. 10.1179/136485906X97453.CrossRef
4.
5.
go back to reference Aspray TJ, Mugusi F, Rashid S, Whiting D, Edwards R, Alberti KG, Unwin NC: Essential Non-Communicable Disease Health Intervention Project: Rural and urban differences in diabetes prevalence in Tanzania: the role of obesity,physical inactivity and urban living. Transactions of the Royal Society of Tropical Medicine & Hygiene. 2000, 94 (6): 637-644. 10.1016/S0035-9203(00)90216-5.CrossRef Aspray TJ, Mugusi F, Rashid S, Whiting D, Edwards R, Alberti KG, Unwin NC: Essential Non-Communicable Disease Health Intervention Project: Rural and urban differences in diabetes prevalence in Tanzania: the role of obesity,physical inactivity and urban living. Transactions of the Royal Society of Tropical Medicine & Hygiene. 2000, 94 (6): 637-644. 10.1016/S0035-9203(00)90216-5.CrossRef
6.
go back to reference Edwards R, Unwin N, Mugusi F, Whiting D, Rashid S, Kissima J, Aspray TJ, Alberti KG: Hypertension prevalence and care in an urban and rural area of Tanzania. Journal of Hypertension. 2000, 18 (2): 145-152. 10.1097/00004872-200018020-00003.CrossRefPubMed Edwards R, Unwin N, Mugusi F, Whiting D, Rashid S, Kissima J, Aspray TJ, Alberti KG: Hypertension prevalence and care in an urban and rural area of Tanzania. Journal of Hypertension. 2000, 18 (2): 145-152. 10.1097/00004872-200018020-00003.CrossRefPubMed
7.
go back to reference Unwin N, Setel P, Rashid S, Mugusi F, Mbanya JC, Kitange H, Hayes L, Edwards R, Aspray T, Alberti KGMM: Non-communicable diseases in sub-Saharan Africa: where do they feature in the health research agenda?. Bulletin of the World Health Organisation. 2001, 79: 947-953. Unwin N, Setel P, Rashid S, Mugusi F, Mbanya JC, Kitange H, Hayes L, Edwards R, Aspray T, Alberti KGMM: Non-communicable diseases in sub-Saharan Africa: where do they feature in the health research agenda?. Bulletin of the World Health Organisation. 2001, 79: 947-953.
8.
go back to reference Walker RW, McLarty DG, Kitange HM, Whiting D, Masuki G, Mtasiwa DM, Machibya H, Unwin N, Alberti KG, for the Adult Morbidity and Mortality Project: Stroke mortality in urban and rural Tanzania. Lancet. 2000, 355 (9216): 1684-1687. 10.1016/S0140-6736(00)02240-6.CrossRefPubMed Walker RW, McLarty DG, Kitange HM, Whiting D, Masuki G, Mtasiwa DM, Machibya H, Unwin N, Alberti KG, for the Adult Morbidity and Mortality Project: Stroke mortality in urban and rural Tanzania. Lancet. 2000, 355 (9216): 1684-1687. 10.1016/S0140-6736(00)02240-6.CrossRefPubMed
9.
go back to reference Popkin BM: The nutrition transition: an overview of world patterns of change. Nutrition Reviews. 2004, 62 (7 Pt 2): S140-S143. 10.1111/j.1753-4887.2004.tb00084.x.CrossRefPubMed Popkin BM: The nutrition transition: an overview of world patterns of change. Nutrition Reviews. 2004, 62 (7 Pt 2): S140-S143. 10.1111/j.1753-4887.2004.tb00084.x.CrossRefPubMed
10.
go back to reference Unwin N, McLarty D, Machibya H, Aspray T, Tamin B, Carlin L, Patel S, Walker M, Alberti KGMM: Changes in blood pressure and lipids associated with rural to urban migration in Tanzania. Journal of Human Hypertension. 2006, 20 (9): 704-706. 10.1038/sj.jhh.1002056.CrossRefPubMed Unwin N, McLarty D, Machibya H, Aspray T, Tamin B, Carlin L, Patel S, Walker M, Alberti KGMM: Changes in blood pressure and lipids associated with rural to urban migration in Tanzania. Journal of Human Hypertension. 2006, 20 (9): 704-706. 10.1038/sj.jhh.1002056.CrossRefPubMed
11.
go back to reference Kitange HM, Machibya H, Black J, Mtasiwa DM, Masuki G, Whiting D, Unwin N, Moshiro C, Klima PM, Lewanga M, Alberti KGMM, McLarty D: Outlook for survivors of childhood in sub-Saharan Africa: adult mortality in Tanzania. BMJ. 1996, 312 (7025): 216-220.CrossRefPubMedPubMedCentral Kitange HM, Machibya H, Black J, Mtasiwa DM, Masuki G, Whiting D, Unwin N, Moshiro C, Klima PM, Lewanga M, Alberti KGMM, McLarty D: Outlook for survivors of childhood in sub-Saharan Africa: adult mortality in Tanzania. BMJ. 1996, 312 (7025): 216-220.CrossRefPubMedPubMedCentral
12.
go back to reference Setel P, Unwin N, Alberti K, Hemed Y: Cause-Specific Adult Mortality: Evidence From Community-Based Surveillance --- Selected Sites, Tanzania, 1992-1998. Morbidity and Mortality Weekly Report. 2000, 49: 416-419. Setel P, Unwin N, Alberti K, Hemed Y: Cause-Specific Adult Mortality: Evidence From Community-Based Surveillance --- Selected Sites, Tanzania, 1992-1998. Morbidity and Mortality Weekly Report. 2000, 49: 416-419.
13.
go back to reference Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clinical Chemistry. 1972, 18 (6): 499-502.PubMed Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clinical Chemistry. 1972, 18 (6): 499-502.PubMed
14.
go back to reference McLarty DG, Swai AB, Kitange HM, Masuki G, Mtinangi BL, Kilima PM, Makene WJ, Chuwa LM, Alberti KGMM: Prevalence of diabetes and impaired glucose tolerance in rural Tanzania. Lancet. 1989, 1: 871-875. 10.1016/S0140-6736(89)92866-3.CrossRefPubMed McLarty DG, Swai AB, Kitange HM, Masuki G, Mtinangi BL, Kilima PM, Makene WJ, Chuwa LM, Alberti KGMM: Prevalence of diabetes and impaired glucose tolerance in rural Tanzania. Lancet. 1989, 1: 871-875. 10.1016/S0140-6736(89)92866-3.CrossRefPubMed
15.
go back to reference Swai AB, McLarty DG, Kitange HM, Kilima PM, Tatalla S, Keen N, Chuwa LM, Alberti KG: Low prevalence of risk factors for coronary heart disease in rural Tanzania. International Journal of Epidemiology. 1993, 22: 651-659. 10.1093/ije/22.4.651.CrossRefPubMed Swai AB, McLarty DG, Kitange HM, Kilima PM, Tatalla S, Keen N, Chuwa LM, Alberti KG: Low prevalence of risk factors for coronary heart disease in rural Tanzania. International Journal of Epidemiology. 1993, 22: 651-659. 10.1093/ije/22.4.651.CrossRefPubMed
16.
go back to reference McLean RA, Sanders WL, Stroup WW: A unified approach to mixed linear models. The American Statistician. 1991, 45: 54-64. 10.2307/2685241. McLean RA, Sanders WL, Stroup WW: A unified approach to mixed linear models. The American Statistician. 1991, 45: 54-64. 10.2307/2685241.
17.
go back to reference Marshall JA, Scarbro S, Shetterly SM, Jones RH, Marshall JA, Scarbro S, Shetterly SM, Jones RH: Improving power with repeated measures: diet and serum lipids. American Journal of Clinical Nutrition. 1998, 67 (5): 934-939.PubMed Marshall JA, Scarbro S, Shetterly SM, Jones RH, Marshall JA, Scarbro S, Shetterly SM, Jones RH: Improving power with repeated measures: diet and serum lipids. American Journal of Clinical Nutrition. 1998, 67 (5): 934-939.PubMed
18.
go back to reference SAS Institute Inc: Statistical Analysis Software. 2009, Cary, North Carolina: SAS Institute Inc SAS Institute Inc: Statistical Analysis Software. 2009, Cary, North Carolina: SAS Institute Inc
19.
go back to reference Tanner M, Kent N, Smith B, Fletcher S, Lewer M: Stability of common biochemical analytes in serum gel tubes subjected to various storage temperatures and times pre-centrifugation. Annals of Clinical Biochemistry. 2008, 45 (Pt 4): 375-379. 10.1258/acb.2007.007183.CrossRefPubMed Tanner M, Kent N, Smith B, Fletcher S, Lewer M: Stability of common biochemical analytes in serum gel tubes subjected to various storage temperatures and times pre-centrifugation. Annals of Clinical Biochemistry. 2008, 45 (Pt 4): 375-379. 10.1258/acb.2007.007183.CrossRefPubMed
20.
go back to reference Bovet P, Gervasoni JP, Ross AG, Mkamba M, Mtasiwa DM, Lengeler C, Burnier M, Paccaud F: Assessing the prevalence of hypertension in populations: are we doing it right?. Journal of Hypertension. 2003, 21 (3): 509-517. 10.1097/00004872-200303000-00016.CrossRefPubMed Bovet P, Gervasoni JP, Ross AG, Mkamba M, Mtasiwa DM, Lengeler C, Burnier M, Paccaud F: Assessing the prevalence of hypertension in populations: are we doing it right?. Journal of Hypertension. 2003, 21 (3): 509-517. 10.1097/00004872-200303000-00016.CrossRefPubMed
21.
go back to reference Poulter NR, Lury JD, Thompson AV: Blood pressures higher in the home than in the clinic in rural Kenya. Journal of Epidemiology & Community Health. 1986, 40 (2): 186-187. 10.1136/jech.40.2.186.CrossRef Poulter NR, Lury JD, Thompson AV: Blood pressures higher in the home than in the clinic in rural Kenya. Journal of Epidemiology & Community Health. 1986, 40 (2): 186-187. 10.1136/jech.40.2.186.CrossRef
22.
go back to reference Poulter NR, Khaw KT, Hopwood BE, Mugambi M, Peart WS, Rose G, Sever PS: The Kenyan Luo migration study: observations on the initiation of a rise in blood pressure. BMJ. 1990, 300 (6730): 967-972. 10.1136/bmj.300.6730.967.CrossRefPubMedPubMedCentral Poulter NR, Khaw KT, Hopwood BE, Mugambi M, Peart WS, Rose G, Sever PS: The Kenyan Luo migration study: observations on the initiation of a rise in blood pressure. BMJ. 1990, 300 (6730): 967-972. 10.1136/bmj.300.6730.967.CrossRefPubMedPubMedCentral
23.
go back to reference Chahoud G, Aude YW, Mehta JL: Dietary recommendations in the prevention and treatment of coronary heart disease: do we have the ideal diet yet?. American Journal of Cardiology. 2004, 94 (10): 1260-1267. 10.1016/j.amjcard.2004.07.109.CrossRefPubMed Chahoud G, Aude YW, Mehta JL: Dietary recommendations in the prevention and treatment of coronary heart disease: do we have the ideal diet yet?. American Journal of Cardiology. 2004, 94 (10): 1260-1267. 10.1016/j.amjcard.2004.07.109.CrossRefPubMed
24.
go back to reference Vorster HH, Venter CS, Wissing MP, Margetts BM: The nutrition and health transition in the North West Province of South Africa: a review of the THUSA (Transition and Health during Urbanisation of South Africans) study. Public Health Nutrition. 2005, 8 (5): 480-490. 10.1079/PHN2005784.CrossRefPubMed Vorster HH, Venter CS, Wissing MP, Margetts BM: The nutrition and health transition in the North West Province of South Africa: a review of the THUSA (Transition and Health during Urbanisation of South Africans) study. Public Health Nutrition. 2005, 8 (5): 480-490. 10.1079/PHN2005784.CrossRefPubMed
Metadata
Title
Rural to urban migration and changes in cardiovascular risk factors in Tanzania: a prospective cohort study
Authors
Nigel Unwin
Peter James
Dorothy McLarty
Harun Machybia
Peter Nkulila
Bushiri Tamin
Mkay Nguluma
Richard McNally
Publication date
01-12-2010
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2010
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-10-272

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