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Published in: BMC Psychiatry 1/2005

Open Access 01-12-2005 | Research article

The hospital anxiety and depression rating scale: A cross-sectional study of psychometrics and case finding abilities in general practice

Authors: Ingrid Olssøn, Arnstein Mykletun, Alv A Dahl

Published in: BMC Psychiatry | Issue 1/2005

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Abstract

Background

General practitioners' (GPs) diagnostic skills lead to underidentification of generalized anxiety disorders (GAD) and major depressive episodes (MDE). Supplement of brief questionnaires could improve the diagnostic accuracy of GPs for these common mental disorders.
The aims of this study were to examine the usefulness of The Hospital Anxiety and Depression Rating Scale (HADS) for GPs by: 1) Examining its psychometrics in the GPs' setting; 2) Testing its case-finding properties compared to patient-rated GAD and MDE (DSM-IV); and 3) Comparing its case finding abilities to that of the GPs using Clinical Global Impression-Severity (CGI-S) rating.

Methods

In a cross-sectional survey study 1,781 patients in three consecutive days in September 2001 attended 141 GPs geographically spread in Norway. Sensitivity, specificity, optimal cut off score, and Area under the curve (AUC) for the HADS and the CGI-S were calculated with Generalized Anxiety Questionnaire (GAS-Q) as reference standard for GAD, and Depression Screening Questionnaire (DSQ) for MDE.

Results

The HADS-A had optimal cut off ≥8 (sensitivity 0.89, specificity 0.75), AUC 0.88 and 76% of patients were correctly classified in relation to GAD. The HADS-D had by optimal cut off ≥8 (sensitivity 0.80 and specificity 0.88) AUC 0.93 and 87% of the patients were correctly classified in relation to MDE. Proportions of the total correctly classified at the CGI-S optimal cut-off ≥3 were 83% of patients for GAD and 81% for MDE.

Conclusion

The results indicate that addition of the patients' HADS scores to GPs' information could improve their diagnostic accuracy of GAD and MDE.
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Literature
1.
go back to reference Üstün TB, Sartorius N: Mental illness in general health care. 1995, Chichester: Wiley Üstün TB, Sartorius N: Mental illness in general health care. 1995, Chichester: Wiley
2.
go back to reference Goldberg D, Steele JJ, Johnsen A, Smith C: Ability of primary care physicians to make accurate ratings of psychiatric symptoms. Arch Gen Psychiatry. 1982, 39: 829-33.CrossRefPubMed Goldberg D, Steele JJ, Johnsen A, Smith C: Ability of primary care physicians to make accurate ratings of psychiatric symptoms. Arch Gen Psychiatry. 1982, 39: 829-33.CrossRefPubMed
3.
go back to reference Jencks SF: Recognition of mental distress and diagnosis of mental disorders in primary care. JAMA. 1985, 253: 1903-7. 10.1001/jama.253.13.1903.CrossRefPubMed Jencks SF: Recognition of mental distress and diagnosis of mental disorders in primary care. JAMA. 1985, 253: 1903-7. 10.1001/jama.253.13.1903.CrossRefPubMed
4.
go back to reference Feinstein RE, Brewer AA, Editors: Primary care psychiatry and behavioral medicine. 1999, New York: Springer Feinstein RE, Brewer AA, Editors: Primary care psychiatry and behavioral medicine. 1999, New York: Springer
5.
go back to reference Munk-Jørgensen P, Fink P, Brevik JI, Dalgard OS, Engberg M, Hansson L, Holm M, Joukamaa M, Karlsson H, Lehtinen V, Nettbladt P, Stefansson C, Sørensem L, Jensen J, Borgquist L, Sandanger I, Nordström G: Psychiatric morbidity inn primary public health care: a multicentre investigation. Part II. Hidden morbidity and choice of treatment. Acta Psychiatr Scand. 1997, 95: 6-12.CrossRefPubMed Munk-Jørgensen P, Fink P, Brevik JI, Dalgard OS, Engberg M, Hansson L, Holm M, Joukamaa M, Karlsson H, Lehtinen V, Nettbladt P, Stefansson C, Sørensem L, Jensen J, Borgquist L, Sandanger I, Nordström G: Psychiatric morbidity inn primary public health care: a multicentre investigation. Part II. Hidden morbidity and choice of treatment. Acta Psychiatr Scand. 1997, 95: 6-12.CrossRefPubMed
6.
go back to reference Kessler RC: The epidemiology of pure and comorbid generalized anxiety disorder: a review and evaluation of recent research. Acta Psychiatr Scand Suppl. 2000, 7-13. 10.1111/j.0065-1591.2000.acp29[dash]02.x. 406 Kessler RC: The epidemiology of pure and comorbid generalized anxiety disorder: a review and evaluation of recent research. Acta Psychiatr Scand Suppl. 2000, 7-13. 10.1111/j.0065-1591.2000.acp29[dash]02.x. 406
7.
go back to reference Olfson M, Marcus SC, Druss B, Elinson L, Tanielian T, Pincus HA: National trends in the outpatient treatment of depression. JAMA. 2002, 287: 203-9. 10.1001/jama.287.2.203.CrossRefPubMed Olfson M, Marcus SC, Druss B, Elinson L, Tanielian T, Pincus HA: National trends in the outpatient treatment of depression. JAMA. 2002, 287: 203-9. 10.1001/jama.287.2.203.CrossRefPubMed
8.
go back to reference Wittchen HU, Kessler RC, Beesdo K, Krause P, Höfler M, Hoyer J: Generalized anxiety and depression in primary care: prevalence, recognition, and management. J Clin Psychiatry. 2002, 63 (Suppl 8): 24-34.PubMed Wittchen HU, Kessler RC, Beesdo K, Krause P, Höfler M, Hoyer J: Generalized anxiety and depression in primary care: prevalence, recognition, and management. J Clin Psychiatry. 2002, 63 (Suppl 8): 24-34.PubMed
9.
go back to reference Henkel V, Mergl R, Kohnen R, Maier W, Möller HJ, Hegerl U: Identifying depression in primary care: a comparison of different methods in a prospective cohort study. BMJ. 2003, 326: 200-201. 10.1136/bmj.326.7382.200.CrossRefPubMedPubMedCentral Henkel V, Mergl R, Kohnen R, Maier W, Möller HJ, Hegerl U: Identifying depression in primary care: a comparison of different methods in a prospective cohort study. BMJ. 2003, 326: 200-201. 10.1136/bmj.326.7382.200.CrossRefPubMedPubMedCentral
10.
go back to reference Hoyer von J, Krause P, Höfler M, Beesdo H, Wittchen HU: When and how well does the family physician recognize generalized anxiety disorders and depressions?. Fortschr Medizin. 2001, 119 (Suppl 1): 26-35. (in German) Hoyer von J, Krause P, Höfler M, Beesdo H, Wittchen HU: When and how well does the family physician recognize generalized anxiety disorders and depressions?. Fortschr Medizin. 2001, 119 (Suppl 1): 26-35. (in German)
11.
go back to reference Beesdo K, Krause P, Höfler M, Witchen HU: Do primary care physicians know generalized anxiety disorders? Estimations of prevalence, attitudes and interventions. Fortschr Medizin. 2001, 119 (Suppl 1): 13-16. (in German) Beesdo K, Krause P, Höfler M, Witchen HU: Do primary care physicians know generalized anxiety disorders? Estimations of prevalence, attitudes and interventions. Fortschr Medizin. 2001, 119 (Suppl 1): 13-16. (in German)
12.
go back to reference Herrmann C: International experiences with the hospital anxiety and depression scale – a review of validation data and clinical results. J Psychosom Res. 1997, 42: 17-41. 10.1016/S0022-3999(96)00216-4.CrossRefPubMed Herrmann C: International experiences with the hospital anxiety and depression scale – a review of validation data and clinical results. J Psychosom Res. 1997, 42: 17-41. 10.1016/S0022-3999(96)00216-4.CrossRefPubMed
13.
go back to reference Bjelland I, Dahl AA, Haug TT, Neckelmann D: The validity of the hospital anxiety and depression scale. An updated literature review. J Psychosom Res. 2002, 52: 69-77. 10.1016/S0022-3999(01)00296-3.CrossRefPubMed Bjelland I, Dahl AA, Haug TT, Neckelmann D: The validity of the hospital anxiety and depression scale. An updated literature review. J Psychosom Res. 2002, 52: 69-77. 10.1016/S0022-3999(01)00296-3.CrossRefPubMed
14.
go back to reference Zigmond AS, Snaith RP: The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983, 67: 361-70.CrossRefPubMed Zigmond AS, Snaith RP: The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983, 67: 361-70.CrossRefPubMed
15.
go back to reference Moorey S, Greer S, Watson M, Gorman C, Rowden L, Tunmore R, Robertson B, Bliss J: The factor structure and factor stability of the hospital anxiety and depression scale in patients with cancer. Br J Psychiatry. 1991, 158: 255-259.CrossRefPubMed Moorey S, Greer S, Watson M, Gorman C, Rowden L, Tunmore R, Robertson B, Bliss J: The factor structure and factor stability of the hospital anxiety and depression scale in patients with cancer. Br J Psychiatry. 1991, 158: 255-259.CrossRefPubMed
16.
go back to reference Mykletun A, Stordal E, Dahl AA: Hospital anxiety and depression (HAD) scale: factor structure, item analyses and internal consistency in a large population. Br J Psychiatry. 2001, 179: 540-544. 10.1192/bjp.179.6.540.CrossRefPubMed Mykletun A, Stordal E, Dahl AA: Hospital anxiety and depression (HAD) scale: factor structure, item analyses and internal consistency in a large population. Br J Psychiatry. 2001, 179: 540-544. 10.1192/bjp.179.6.540.CrossRefPubMed
17.
go back to reference EL Rufaie OE, Absood GH: Retesting the validity of the arabic version of the hospital anxiety and depression (HAD) scale in primary heath care. Soc Psychiatry Psychiatr Epidemiol. 1995, 30: 26-31. 10.1007/BF00784431.CrossRefPubMed EL Rufaie OE, Absood GH: Retesting the validity of the arabic version of the hospital anxiety and depression (HAD) scale in primary heath care. Soc Psychiatry Psychiatr Epidemiol. 1995, 30: 26-31. 10.1007/BF00784431.CrossRefPubMed
18.
go back to reference Lam CL, Pan PC, Chan AW, Chan CY, Munro C: Can the hospital anxiety and depression (HAD) scale be used on Chinese elderly in general practice?. Family Pract. 1995, 12: 149-154.CrossRef Lam CL, Pan PC, Chan AW, Chan CY, Munro C: Can the hospital anxiety and depression (HAD) scale be used on Chinese elderly in general practice?. Family Pract. 1995, 12: 149-154.CrossRef
19.
go back to reference Wilkinson MJ, Barczak P: Psychiatric screening in general practice: comparison of the general health questionnaire and the hospital anxiety depression scale. J Royal Coll Gen Practit. 1988, 38: 311-313. Wilkinson MJ, Barczak P: Psychiatric screening in general practice: comparison of the general health questionnaire and the hospital anxiety depression scale. J Royal Coll Gen Practit. 1988, 38: 311-313.
20.
go back to reference Löwe B, Spitzer RL, Gräfe K, Kroenke K, Quenter A, Zipfel S, Buchholz C, Witte S, Herzog W: Comparative validity of three screening questionnaires for DSM-IV depressive disorders and physicians diagnoses. J Affect Dis. 2004, 78: 131-140. 10.1016/S0165-0327(02)00237-9.CrossRefPubMed Löwe B, Spitzer RL, Gräfe K, Kroenke K, Quenter A, Zipfel S, Buchholz C, Witte S, Herzog W: Comparative validity of three screening questionnaires for DSM-IV depressive disorders and physicians diagnoses. J Affect Dis. 2004, 78: 131-140. 10.1016/S0165-0327(02)00237-9.CrossRefPubMed
21.
go back to reference Allgulander C, Nilsson B: A nationwide study in primary health care. One out of four patients suffers from anxiety and depression. Lakartidningen. 2003, 100: 832-838. (in Swedish)PubMed Allgulander C, Nilsson B: A nationwide study in primary health care. One out of four patients suffers from anxiety and depression. Lakartidningen. 2003, 100: 832-838. (in Swedish)PubMed
22.
go back to reference Wittchen HU, Boyer P: Sensitivity and specificity of the anxiety screening questionnaire (ASQ-15). Br J Psychiatry. 1998, 173 (Suppl 34): 10-17. Wittchen HU, Boyer P: Sensitivity and specificity of the anxiety screening questionnaire (ASQ-15). Br J Psychiatry. 1998, 173 (Suppl 34): 10-17.
23.
go back to reference Krause P, Wittchen HU, Höfler M, Winter S, Spiegel B, Pfister H: Generalisierte angst und depression in der allgemeinartztpraxis (GAD-P). Fortschr Medizin. 2001, 119 (suppl 1): 5-12. Krause P, Wittchen HU, Höfler M, Winter S, Spiegel B, Pfister H: Generalisierte angst und depression in der allgemeinartztpraxis (GAD-P). Fortschr Medizin. 2001, 119 (suppl 1): 5-12.
24.
go back to reference Winter S, Wittchen HU, Höfler M, Spiegel B, Ormel H, Müller N, Pfister H: Design und metoden der studie "Depression 2000". Fortschr Medizin. 2000, 118 (suppl 1): 11-21. Winter S, Wittchen HU, Höfler M, Spiegel B, Ormel H, Müller N, Pfister H: Design und metoden der studie "Depression 2000". Fortschr Medizin. 2000, 118 (suppl 1): 11-21.
25.
go back to reference Höfler M., Wittchen HU: Why do primary care doctors diagnose depression when diagnostic criteria are not met?. Int J Methods Psychiat Res. 2000, 9: 110-120.CrossRef Höfler M., Wittchen HU: Why do primary care doctors diagnose depression when diagnostic criteria are not met?. Int J Methods Psychiat Res. 2000, 9: 110-120.CrossRef
26.
go back to reference Wittchen HU, Höfler M, Meister W: Prevalence and recognition of depressive syndromes in German primary care settings: poorly recognized and treated?. Int Clin Psychopharmacol. 2001, 16: 121-135. 10.1097/00004850-200105000-00001.CrossRefPubMed Wittchen HU, Höfler M, Meister W: Prevalence and recognition of depressive syndromes in German primary care settings: poorly recognized and treated?. Int Clin Psychopharmacol. 2001, 16: 121-135. 10.1097/00004850-200105000-00001.CrossRefPubMed
27.
go back to reference Watson D, Clark LA, Weber K, Assenheimer JC, Strauss ME, McCormick RA: Testing a tripartite model: II. Exploring the symptom structure of anxiety and depression in student, adult, and patient samples. J Abnorm Psychol. 1995, 104: 15-25. 10.1037/0021-843X.104.1.15.CrossRefPubMed Watson D, Clark LA, Weber K, Assenheimer JC, Strauss ME, McCormick RA: Testing a tripartite model: II. Exploring the symptom structure of anxiety and depression in student, adult, and patient samples. J Abnorm Psychol. 1995, 104: 15-25. 10.1037/0021-843X.104.1.15.CrossRefPubMed
28.
go back to reference Guy W: Clinical global impressions scale. ECDEU assessment manual for psychopharmacology. US Dept Health, Education, and Welfare publication (AMD) 76–338. 1976, Rockville, Md: National Institute of Mental Health, 221-227. Guy W: Clinical global impressions scale. ECDEU assessment manual for psychopharmacology. US Dept Health, Education, and Welfare publication (AMD) 76–338. 1976, Rockville, Md: National Institute of Mental Health, 221-227.
30.
go back to reference Engstrom S, Foldevi M, Borgquist L: Is general practice effective? A systematic literature review. Scand J Prim Health Care. 2001, 19: 131-144. 10.1080/028134301750235394.CrossRefPubMed Engstrom S, Foldevi M, Borgquist L: Is general practice effective? A systematic literature review. Scand J Prim Health Care. 2001, 19: 131-144. 10.1080/028134301750235394.CrossRefPubMed
31.
go back to reference Crawford JR, Henry JD, Crombie C, Taylor EP: Normative data for the HADS from a large non-clinical sample. Br J Clin Psychol. 2001, 40: 429-434. 10.1348/014466501163904.CrossRefPubMed Crawford JR, Henry JD, Crombie C, Taylor EP: Normative data for the HADS from a large non-clinical sample. Br J Clin Psychol. 2001, 40: 429-434. 10.1348/014466501163904.CrossRefPubMed
32.
go back to reference Spinhoven PH, Ormel J, Sloekers PPA, Kempen GI, Speckens AE, Van Hemert AM: A validation study of the hospital anxiety and depression scale (HADS) in different groups of Dutch subjects. Psychol Med. 1997, 27: 363-370. 10.1017/S0033291796004382.CrossRefPubMed Spinhoven PH, Ormel J, Sloekers PPA, Kempen GI, Speckens AE, Van Hemert AM: A validation study of the hospital anxiety and depression scale (HADS) in different groups of Dutch subjects. Psychol Med. 1997, 27: 363-370. 10.1017/S0033291796004382.CrossRefPubMed
Metadata
Title
The hospital anxiety and depression rating scale: A cross-sectional study of psychometrics and case finding abilities in general practice
Authors
Ingrid Olssøn
Arnstein Mykletun
Alv A Dahl
Publication date
01-12-2005
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2005
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/1471-244X-5-46

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