Skip to main content
Top
Published in: BMC Psychiatry 1/2014

Open Access 01-12-2014 | Research article

“Clozapine makes me quite drowsy, so when I wake up in the morning those first cups of coffee are really handy”: an exploratory qualitative study of excessive caffeine consumption among individuals with schizophrenia

Authors: Lisa Thompson, Amy Pennay, Adam Zimmermann, Merrilee Cox, Dan I Lubman

Published in: BMC Psychiatry | Issue 1/2014

Login to get access

Abstract

Background

Research has shown that individuals with schizophrenia use caffeine at higher rates than the general population; however, no qualitative research has been undertaken investigating problematic caffeine use and its effects on this population. This article explores the role of caffeine consumption in the lives of people with schizophrenia through a narrative analysis of the attitudes and beliefs associated with this practice, and how these, in turn, influence caffeine consumption.

Methods

A qualitative study was undertaken with individuals who had previously scored in either a ‘moderate’ or ‘high’ risk category for caffeine use on the Alcohol, Smoking and Substance Involvement Screening Tool (ASSIST). In-depth interviews were undertaken with 20 individuals, and transcripts were analysed thematically to identify prominent perspectives.

Results

Consistent with previous literature, participants’ caffeine consumption was driven largely by its stimulating properties; however, participants also identified ‘cravings’ as an important motivating factor. Participants’ behaviours related to caffeine consumption seemed to be tempered by their previous experiences of consumption; if participants had experienced positive effects such as alertness or relaxation in the past, their use was maintained at a similar level or increased. Conversely, participants who anticipated negative consequences often altered their patterns of caffeine consumption; for example, by substituting caffeinated drinks that minimised or ceased their experience of negative side effects for those that directly caused such impacts. Overall, participants largely identified caffeine consumption as a highly meaningful activity, which provided structure to their day and facilitated opportunities for social interaction.

Conclusions

The inconsistencies between individuals’ beliefs about their health and the actual risk of harm associated with health-related behaviours present significant and ongoing challenges for the implementation of relevant and effective strategies for health promotion among individuals diagnosed with mental illness. As a starting point, it would be worthwhile for services engaging with people diagnosed with mental illness, and in particular schizophrenia, to consider implementing caffeine-related health literacy strategies to educate consumers about the risk of excessive caffeine consumption and the interactions between caffeine and antipsychotic medications.
Literature
1.
go back to reference Hovermale Simmons D: Caffeine and its effect on persons with mental disorders. Arch Psychiatr Nurs. 1996, X: 116-122.CrossRef Hovermale Simmons D: Caffeine and its effect on persons with mental disorders. Arch Psychiatr Nurs. 1996, X: 116-122.CrossRef
2.
go back to reference Carey KB, Maisto SA, Carey MP, Gordon CM, Correia CJ: Use of legal drugs by psychiatric outpatients: benefits, costs, and change. Cogn Behav Pract. 1999, 6: 15-22. 10.1016/S1077-7229(99)80037-6.CrossRefPubMedPubMedCentral Carey KB, Maisto SA, Carey MP, Gordon CM, Correia CJ: Use of legal drugs by psychiatric outpatients: benefits, costs, and change. Cogn Behav Pract. 1999, 6: 15-22. 10.1016/S1077-7229(99)80037-6.CrossRefPubMedPubMedCentral
3.
go back to reference Lucas PB, Pickar D, Kelsoe J, Rapaport M, Pato C, Hommer D: Effects of the acute administration of caffeine in patients with schizophrenia. Biol Psychiatry. 1990, 28: 35-40. 10.1016/0006-3223(90)90429-6.CrossRefPubMed Lucas PB, Pickar D, Kelsoe J, Rapaport M, Pato C, Hommer D: Effects of the acute administration of caffeine in patients with schizophrenia. Biol Psychiatry. 1990, 28: 35-40. 10.1016/0006-3223(90)90429-6.CrossRefPubMed
4.
go back to reference Shisslak C, Beutler L, Scheiber S, Gaines J, La Wall J, Crago M: Patterns of caffeine use and prescribed medications in psychiatric inpatients. Psychol Rep. 1985, 57: 39-42. 10.2466/pr0.1985.57.1.39.CrossRefPubMed Shisslak C, Beutler L, Scheiber S, Gaines J, La Wall J, Crago M: Patterns of caffeine use and prescribed medications in psychiatric inpatients. Psychol Rep. 1985, 57: 39-42. 10.2466/pr0.1985.57.1.39.CrossRefPubMed
5.
go back to reference Winstead D: Coffee consumption among psychiatric inpatients. Am J Psychiatry. 1976, 133: 1447-1450.CrossRefPubMed Winstead D: Coffee consumption among psychiatric inpatients. Am J Psychiatry. 1976, 133: 1447-1450.CrossRefPubMed
6.
go back to reference Strassnig M, Brar JS, Ganguli R: Increased caffeine and nicotine consumption in community-dwelling patients with schizophrenia. Schizophr Res. 2006, 86: 269-275. 10.1016/j.schres.2006.05.013.CrossRefPubMed Strassnig M, Brar JS, Ganguli R: Increased caffeine and nicotine consumption in community-dwelling patients with schizophrenia. Schizophr Res. 2006, 86: 269-275. 10.1016/j.schres.2006.05.013.CrossRefPubMed
7.
go back to reference Gurpegui M, Aguilar MC, Martinez-Ortega JM, Diaz FJ, de Leon J: Caffeine intake in outpatients with Schizophrenia. Schizophr Bull. 2004, 30: 935-945. 10.1093/oxfordjournals.schbul.a007143.CrossRefPubMed Gurpegui M, Aguilar MC, Martinez-Ortega JM, Diaz FJ, de Leon J: Caffeine intake in outpatients with Schizophrenia. Schizophr Bull. 2004, 30: 935-945. 10.1093/oxfordjournals.schbul.a007143.CrossRefPubMed
8.
go back to reference Gurpegui M, Aguilar MC, Martinez-Ortega JM, Jurado D, Diaz FJ, Quintana HM, de Leon J: Fewer but heavier caffeine consumers in schizophrenia: a case- control study. Schizophr Res. 2006, 86: 276-283. 10.1016/j.schres.2006.04.022.CrossRefPubMed Gurpegui M, Aguilar MC, Martinez-Ortega JM, Jurado D, Diaz FJ, Quintana HM, de Leon J: Fewer but heavier caffeine consumers in schizophrenia: a case- control study. Schizophr Res. 2006, 86: 276-283. 10.1016/j.schres.2006.04.022.CrossRefPubMed
9.
go back to reference Larson CA, Carey KB: Caffeine: brewing trouble in mental health settings?. Prof Psychol-Res Pr. 1998, 29: 373-376.CrossRef Larson CA, Carey KB: Caffeine: brewing trouble in mental health settings?. Prof Psychol-Res Pr. 1998, 29: 373-376.CrossRef
10.
go back to reference Fowler IL, Carr VJ, Carter NT, Lewin TJ: Patterns of current and lifetime substance use in schizophrenia. Schizophr Bull. 1998, 24: 443-455. 10.1093/oxfordjournals.schbul.a033339.CrossRefPubMed Fowler IL, Carr VJ, Carter NT, Lewin TJ: Patterns of current and lifetime substance use in schizophrenia. Schizophr Bull. 1998, 24: 443-455. 10.1093/oxfordjournals.schbul.a033339.CrossRefPubMed
11.
go back to reference Brown J, Kreiger N, Darlington GA, Sloan M: Misclassification of exposure: coffee as a surrogate for caffeine intake. Am J Epidemiol. 2001, 153: 815-820. 10.1093/aje/153.8.815.CrossRefPubMed Brown J, Kreiger N, Darlington GA, Sloan M: Misclassification of exposure: coffee as a surrogate for caffeine intake. Am J Epidemiol. 2001, 153: 815-820. 10.1093/aje/153.8.815.CrossRefPubMed
12.
go back to reference Zimmermann A, Lubman DI, Cox M: Tobacco, caffeine, alcohol and illicit substance Use among consumers of A National Psychiatric Disability Support Service. Int J Ment Health Addict. 2012, 10: 722-736. 10.1007/s11469-011-9373-y.CrossRef Zimmermann A, Lubman DI, Cox M: Tobacco, caffeine, alcohol and illicit substance Use among consumers of A National Psychiatric Disability Support Service. Int J Ment Health Addict. 2012, 10: 722-736. 10.1007/s11469-011-9373-y.CrossRef
14.
go back to reference Koczapski A, Paredes J, Kogan C, Ledwidge B, Higenbottam J: Multisubstance intoxication among schizophrenic inpatients: reply to Hyde. Schizophr Bull. 1990, 16: 373-375. 10.1093/schbul/16.3.373.CrossRef Koczapski A, Paredes J, Kogan C, Ledwidge B, Higenbottam J: Multisubstance intoxication among schizophrenic inpatients: reply to Hyde. Schizophr Bull. 1990, 16: 373-375. 10.1093/schbul/16.3.373.CrossRef
15.
go back to reference Braun V, Clarke V: Using thematic analysis in psychology. Qual Res Psychol. 2006, 3: 77-101. 10.1191/1478088706qp063oa.CrossRef Braun V, Clarke V: Using thematic analysis in psychology. Qual Res Psychol. 2006, 3: 77-101. 10.1191/1478088706qp063oa.CrossRef
16.
go back to reference Larson M, Watts S, Clifton E: Giving voice and making sense in interpretive phenomenological analysis. Qual Res Psychol. 2006, 3: 102-120. 10.1191/1478088706qp062oa.CrossRef Larson M, Watts S, Clifton E: Giving voice and making sense in interpretive phenomenological analysis. Qual Res Psychol. 2006, 3: 102-120. 10.1191/1478088706qp062oa.CrossRef
17.
go back to reference Hides L, Cotton S, Berger G, Gleeson J, O’Donnell C, Proffitt T, Lubman DI: The reliability and validity of the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) in first-episode psychosis. Addict Behav. 2009, 34: 821-845. 10.1016/j.addbeh.2009.03.001.CrossRefPubMed Hides L, Cotton S, Berger G, Gleeson J, O’Donnell C, Proffitt T, Lubman DI: The reliability and validity of the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) in first-episode psychosis. Addict Behav. 2009, 34: 821-845. 10.1016/j.addbeh.2009.03.001.CrossRefPubMed
18.
go back to reference Guest G, Bunce A, Johnson L: How many interviews are enough? An experiment with data saturation and variability. Field Methods. 2006, 18: 59-82. 10.1177/1525822X05279903.CrossRef Guest G, Bunce A, Johnson L: How many interviews are enough? An experiment with data saturation and variability. Field Methods. 2006, 18: 59-82. 10.1177/1525822X05279903.CrossRef
19.
20.
go back to reference Proudfoot H, Teesson M, Brewin E, Gournay K: Comorbidity and Delivery of Services. Comorbid Mental Disorders and Substance Use Disorders: Epidemiology, Prevention and Treatment. Edited by: Proudfoot H. 2003, Canberra: Commonwealth of Australia Proudfoot H, Teesson M, Brewin E, Gournay K: Comorbidity and Delivery of Services. Comorbid Mental Disorders and Substance Use Disorders: Epidemiology, Prevention and Treatment. Edited by: Proudfoot H. 2003, Canberra: Commonwealth of Australia
21.
go back to reference Adolfo AB, AhnAllen CG, Tidey TW: Effects of smoking cues on caffeine urges in heavy smokers and caffeine consumers with and without schizophrenia. Schizophr Res. 2009, 2–3: 192-197.CrossRef Adolfo AB, AhnAllen CG, Tidey TW: Effects of smoking cues on caffeine urges in heavy smokers and caffeine consumers with and without schizophrenia. Schizophr Res. 2009, 2–3: 192-197.CrossRef
22.
go back to reference Jones HE, Griffiths RR: Oral caffeine maintenance potentiates the reinforcing and stimulant subjective effects of intravenous nicotine in cigarette smokers. Psychopharmacology (Berl). 2003, 165: 280-290. Jones HE, Griffiths RR: Oral caffeine maintenance potentiates the reinforcing and stimulant subjective effects of intravenous nicotine in cigarette smokers. Psychopharmacology (Berl). 2003, 165: 280-290.
23.
go back to reference Gandhi K, Williams J, Menza M, Galazyn M, Benowitz N: Higher serum caffeine in smokers with schizophrenia compared to smoking controls. Drug Alcohol Depen. 2010, 110: 151-155. 10.1016/j.drugalcdep.2010.01.021.CrossRef Gandhi K, Williams J, Menza M, Galazyn M, Benowitz N: Higher serum caffeine in smokers with schizophrenia compared to smoking controls. Drug Alcohol Depen. 2010, 110: 151-155. 10.1016/j.drugalcdep.2010.01.021.CrossRef
24.
go back to reference Elisha D, Castle D, Hocking B: Reducing social isolation in people with mental illness: the role of the psychiatrist. Australas Psychiatry. 2006, 14: 281-284. 10.1111/j.1440-1665.2006.02287.x.CrossRefPubMed Elisha D, Castle D, Hocking B: Reducing social isolation in people with mental illness: the role of the psychiatrist. Australas Psychiatry. 2006, 14: 281-284. 10.1111/j.1440-1665.2006.02287.x.CrossRefPubMed
25.
go back to reference Hooley JM: Social factors in schizophrenia. Curr Dir Psychol. 2010, 19: 238-242. 10.1177/0963721410377597.CrossRef Hooley JM: Social factors in schizophrenia. Curr Dir Psychol. 2010, 19: 238-242. 10.1177/0963721410377597.CrossRef
26.
go back to reference Lloyd C, Sullivan D, Williams P: Perceptions of social stigma and its effect on interpersonal relationships of young males who experience a psychotic disorder. Aust Occup Therap J. 2005, 52: 243-250. 10.1111/j.1440-1630.2005.00504.x.CrossRef Lloyd C, Sullivan D, Williams P: Perceptions of social stigma and its effect on interpersonal relationships of young males who experience a psychotic disorder. Aust Occup Therap J. 2005, 52: 243-250. 10.1111/j.1440-1630.2005.00504.x.CrossRef
27.
go back to reference Rajkumar AP, Poonkuzhali B, Kuruvilla A, Jacob M, Jacob KS: Clinical indicators of serum clozapine levels in patients with treatment-resistant schizophrenia. Int Clin Psychopharm. 2013, 28: 50-56. 10.1097/YIC.0b013e32835ac9da.CrossRef Rajkumar AP, Poonkuzhali B, Kuruvilla A, Jacob M, Jacob KS: Clinical indicators of serum clozapine levels in patients with treatment-resistant schizophrenia. Int Clin Psychopharm. 2013, 28: 50-56. 10.1097/YIC.0b013e32835ac9da.CrossRef
28.
go back to reference Dratcu L, Grandison A, McKay G, Bamidele A, Vasukevan V: Clozapine-resistant psychosis, smoking, and caffeine: managing the neglected effects of substances that our patients consume every day. Am J Ther. 2007, 14: 314-318. 10.1097/01.pap.0000249958.96498.ce.CrossRefPubMed Dratcu L, Grandison A, McKay G, Bamidele A, Vasukevan V: Clozapine-resistant psychosis, smoking, and caffeine: managing the neglected effects of substances that our patients consume every day. Am J Ther. 2007, 14: 314-318. 10.1097/01.pap.0000249958.96498.ce.CrossRefPubMed
29.
go back to reference Peet R: Diet, diabetes and schizophrenia: review and hypothesis. Brit J Psychiat. 2004, 204: s102-s105.CrossRef Peet R: Diet, diabetes and schizophrenia: review and hypothesis. Brit J Psychiat. 2004, 204: s102-s105.CrossRef
31.
go back to reference Aleman A, Hijman R, de Haan EHF, Kahn RS: Memory impairment in schizophrenia: a meta-analysis. Am J Psychiatry. 1999, 156: 1358-1366.PubMed Aleman A, Hijman R, de Haan EHF, Kahn RS: Memory impairment in schizophrenia: a meta-analysis. Am J Psychiatry. 1999, 156: 1358-1366.PubMed
32.
go back to reference Moskowitz DS, Young SN: Ecological momentary assessment: what it is and why it is a method of the future in clinical psychopharmacology. J Psychiatry Neurosci. 2006, 31: 13-20.PubMedPubMedCentral Moskowitz DS, Young SN: Ecological momentary assessment: what it is and why it is a method of the future in clinical psychopharmacology. J Psychiatry Neurosci. 2006, 31: 13-20.PubMedPubMedCentral
Metadata
Title
“Clozapine makes me quite drowsy, so when I wake up in the morning those first cups of coffee are really handy”: an exploratory qualitative study of excessive caffeine consumption among individuals with schizophrenia
Authors
Lisa Thompson
Amy Pennay
Adam Zimmermann
Merrilee Cox
Dan I Lubman
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2014
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/1471-244X-14-116

Other articles of this Issue 1/2014

BMC Psychiatry 1/2014 Go to the issue