Skip to main content
Top
Published in: BMC Psychiatry 1/2013

Open Access 01-12-2013 | Research article

The psychosocial difficulties in brain disorders that explain short term changes in health outcomes

Authors: Alarcos Cieza, Cristina Bostan, Jose Luis Ayuso-Mateos, Cornelia Oberhauser, Jerome Bickenbach, Alberto Raggi, Matilde Leonardi, Eduard Vieta, Somnath Chatterji

Published in: BMC Psychiatry | Issue 1/2013

Login to get access

Abstract

Background

This study identifies a set of psychosocial difficulties that are associated with short term changes in health outcomes across a heterogeneous set of brain disorders, neurological and psychiatric.

Methods

Longitudinal observational study over approximately 12 weeks with three time points of assessment and 741 patients with bipolar disorders, depression, migraine, multiple sclerosis, parkinson’s disease, stroke and traumatic brain injury. The data on disability was collected with the checklist of the International Classification of Functioning, Disability and Health. The selected health outcomes were the Short Form 36 and the World Health Organization Disability Assessment Schedule. Multilevel models for change were applied controlling for age, gender and disease severity.

Results

The psychosocial difficulties that explain the variability and change over time of the selected health outcomes were energy and drive, sleep, and emotional functions, and a broad range of activities and participation domains, such as solving problems, conversation, areas of mobility and self-care, relationships, community life and recreation and leisure.

Conclusions

Our findings are of interest to researchers and clinicians for interventions and health systems planning as they show that in addition to difficulties that are diagnostic criteria of these disorders, there are other difficulties that explain small changes in health outcomes over short periods of time.
Appendix
Available only for authorised users
Literature
1.
go back to reference Wittchen HU, Jacobi F: Size and burden of mental disorders in Europe—a critical review and appraisal of 27 studies. Eur Neuropsychopharmacol. 2005, 15: 357-376. 10.1016/j.euroneuro.2005.04.012.CrossRefPubMed Wittchen HU, Jacobi F: Size and burden of mental disorders in Europe—a critical review and appraisal of 27 studies. Eur Neuropsychopharmacol. 2005, 15: 357-376. 10.1016/j.euroneuro.2005.04.012.CrossRefPubMed
2.
go back to reference Wittchen HU: Critical issues in the evaluation of comorbidity of psychiatric disorders. Br J Psychiatry. 1996, 168 (Suppl.30): 9-16. Wittchen HU: Critical issues in the evaluation of comorbidity of psychiatric disorders. Br J Psychiatry. 1996, 168 (Suppl.30): 9-16.
3.
4.
go back to reference Olesen J, Leonardi M: The burden of brain diseases in Europe. Eur J Neurol. 2003, 10: 471-477. 10.1046/j.1468-1331.2003.00682.x.CrossRefPubMed Olesen J, Leonardi M: The burden of brain diseases in Europe. Eur J Neurol. 2003, 10: 471-477. 10.1046/j.1468-1331.2003.00682.x.CrossRefPubMed
5.
go back to reference The Global Burden of Disease: A comprehensive assessment of mortality and disability from diseases, injuries and risk factors in 1990 and projected to 2020. Edited by: Murray CJL, Lopez AD. 1996, Cambridge, Massachusetts: Harvard School of Public Health on behalf of the World Health Organization and the World Bank The Global Burden of Disease: A comprehensive assessment of mortality and disability from diseases, injuries and risk factors in 1990 and projected to 2020. Edited by: Murray CJL, Lopez AD. 1996, Cambridge, Massachusetts: Harvard School of Public Health on behalf of the World Health Organization and the World Bank
6.
go back to reference World Health Organization: Neurological Disorders: public health challenges. 2006, Geneva, Switzerland: WHO World Health Organization: Neurological Disorders: public health challenges. 2006, Geneva, Switzerland: WHO
7.
go back to reference World Health Organization: Mental Health Atlas. 2005, Geneva, Switzerland: WHO World Health Organization: Mental Health Atlas. 2005, Geneva, Switzerland: WHO
8.
go back to reference World Health Organization: Atlas: Country Resources for Neurological Disorders. 2004, Geneva, Switzerland: WHO World Health Organization: Atlas: Country Resources for Neurological Disorders. 2004, Geneva, Switzerland: WHO
9.
go back to reference World Health Organization: International Classification of Functioning, Disability and Health: ICF. 2001, Geneva, Switzerland: WHO World Health Organization: International Classification of Functioning, Disability and Health: ICF. 2001, Geneva, Switzerland: WHO
10.
go back to reference Holper L, Coenen M, Weise A, Stucki G, Cieza A, Kesselring J: Characterization of functioning in multiple sclerosis using the ICF. J Neurol. 2010, 257 (1): 103-113. 10.1007/s00415-009-5282-4.CrossRefPubMed Holper L, Coenen M, Weise A, Stucki G, Cieza A, Kesselring J: Characterization of functioning in multiple sclerosis using the ICF. J Neurol. 2010, 257 (1): 103-113. 10.1007/s00415-009-5282-4.CrossRefPubMed
11.
go back to reference Cieza A, Chatterji S, Andersen C, Cantista P, Herceg M, Melvin J, Stucki G, de Bie R: ICF core sets for depression. J Rehabil Med. 2004, 44: 128-134.CrossRefPubMed Cieza A, Chatterji S, Andersen C, Cantista P, Herceg M, Melvin J, Stucki G, de Bie R: ICF core sets for depression. J Rehabil Med. 2004, 44: 128-134.CrossRefPubMed
12.
go back to reference Aiachini B, Pisoni C, Cieza A, Cazzulani B, Giustini A, Pistarini C: Developing ICF core set for subjects with traumatic brain injury: an Italian clinical perspective. Eur J Phys Rehabil Med. 2010, 46 (1): 27-36.PubMed Aiachini B, Pisoni C, Cieza A, Cazzulani B, Giustini A, Pistarini C: Developing ICF core set for subjects with traumatic brain injury: an Italian clinical perspective. Eur J Phys Rehabil Med. 2010, 46 (1): 27-36.PubMed
13.
go back to reference Avila CC, Cabello M, Cieza A, Vieta E, Ayuso-Mateos JL: Functioning and disability in bipolar disorders: a systematic review of literature using the ICF as a reference. Bipolar Disord. 2010, 12 (5): 473-482. 10.1111/j.1399-5618.2010.00833.x.CrossRefPubMed Avila CC, Cabello M, Cieza A, Vieta E, Ayuso-Mateos JL: Functioning and disability in bipolar disorders: a systematic review of literature using the ICF as a reference. Bipolar Disord. 2010, 12 (5): 473-482. 10.1111/j.1399-5618.2010.00833.x.CrossRefPubMed
14.
go back to reference Raggi A, Leonardi M, Ajovalasit D, D’Amico D, Bussone G: Disability and functional profiles of patients with migraine measured with ICF classification. Int J Rehabil Res. 2010, 32: 225-231.CrossRef Raggi A, Leonardi M, Ajovalasit D, D’Amico D, Bussone G: Disability and functional profiles of patients with migraine measured with ICF classification. Int J Rehabil Res. 2010, 32: 225-231.CrossRef
15.
go back to reference Wittchen HU, Jacobi F, Rehm J, Gustavsson A, Svensson M, Jönsson B, Olesen J, Allgulander C, Alonso J, Faravelli C, Fratiglioni L, Jennum P, Lieb R, Maercker A, van Os J, Preisig M, Salvador-Carulla L, Simon R, Steinhausen HC: The size and burden of mental disorders and other disorders of the brain in Europe 2010. Eur Neuropsychopharmacol. 2011, 21 (9): 655-679. 10.1016/j.euroneuro.2011.07.018.CrossRefPubMed Wittchen HU, Jacobi F, Rehm J, Gustavsson A, Svensson M, Jönsson B, Olesen J, Allgulander C, Alonso J, Faravelli C, Fratiglioni L, Jennum P, Lieb R, Maercker A, van Os J, Preisig M, Salvador-Carulla L, Simon R, Steinhausen HC: The size and burden of mental disorders and other disorders of the brain in Europe 2010. Eur Neuropsychopharmacol. 2011, 21 (9): 655-679. 10.1016/j.euroneuro.2011.07.018.CrossRefPubMed
16.
go back to reference World Health Organization: ICF Checklist Version 2.1a, Clinical Form for International Classification of Functioning, Disability and Health: ICF. 2001, Geneva, Switzerland: WHO World Health Organization: ICF Checklist Version 2.1a, Clinical Form for International Classification of Functioning, Disability and Health: ICF. 2001, Geneva, Switzerland: WHO
17.
go back to reference Ware JE, Sherbourne CD: The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992, 30: 473-483. 10.1097/00005650-199206000-00002.CrossRefPubMed Ware JE, Sherbourne CD: The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992, 30: 473-483. 10.1097/00005650-199206000-00002.CrossRefPubMed
18.
go back to reference Üstün TB, Kostanjsek N, Chatterji S, Rehm J: Measuring Health and Disability: Manual for WHO Disability Assessment Schedule (WHODAS 2.0). 2010, Geneva, Switzerland: WHO Üstün TB, Kostanjsek N, Chatterji S, Rehm J: Measuring Health and Disability: Manual for WHO Disability Assessment Schedule (WHODAS 2.0). 2010, Geneva, Switzerland: WHO
19.
go back to reference Garin O, Ayuso-Mateos JL, Almansa J, Nieto M, Chatterji S, Vilagut G, Alonso J, Cieza A, Svestkova O, Burger H, Racca V, Francescutti C, Vieta E, Kostanjsek N, Raggi A, Leonardi M, Ferrer M, the MHADIE consortium: Validation of the “World Health Organization Disability Assessment Schedule, WHODAS-2” in patients with chronic diseases. Health Qual Life Outcomes. 2010, 8: 51-10.1186/1477-7525-8-51.CrossRefPubMedPubMedCentral Garin O, Ayuso-Mateos JL, Almansa J, Nieto M, Chatterji S, Vilagut G, Alonso J, Cieza A, Svestkova O, Burger H, Racca V, Francescutti C, Vieta E, Kostanjsek N, Raggi A, Leonardi M, Ferrer M, the MHADIE consortium: Validation of the “World Health Organization Disability Assessment Schedule, WHODAS-2” in patients with chronic diseases. Health Qual Life Outcomes. 2010, 8: 51-10.1186/1477-7525-8-51.CrossRefPubMedPubMedCentral
20.
go back to reference Francescutti C, Fusaro G, Leonardi M, Martinuzzi A, Sala M, Russo E, Frare M, Pradal M, Zampogna D, Cosentino A, Raggi A: Italian ICF training programs: describing and promoting human functioning and research. Disabil Rehabil. 2009, 31: S46-S49. 10.3109/09638280903317757.CrossRefPubMed Francescutti C, Fusaro G, Leonardi M, Martinuzzi A, Sala M, Russo E, Frare M, Pradal M, Zampogna D, Cosentino A, Raggi A: Italian ICF training programs: describing and promoting human functioning and research. Disabil Rehabil. 2009, 31: S46-S49. 10.3109/09638280903317757.CrossRefPubMed
21.
go back to reference World Health Organization: World Health Report 2000. The world health report 2000 - Health systems: improving performance. 2000, Geneva, Switzerland: WHO World Health Organization: World Health Report 2000. The world health report 2000 - Health systems: improving performance. 2000, Geneva, Switzerland: WHO
22.
go back to reference The WHO world mental health surveys. Global perspectives of mental health surveys. Edited by: Kessler RC, Ustun B. 2008, New York: Cambridge University Press, First The WHO world mental health surveys. Global perspectives of mental health surveys. Edited by: Kessler RC, Ustun B. 2008, New York: Cambridge University Press, First
23.
go back to reference Cieza A, Stucki G: Content comparison of Health Related Quality of Life (HRQOL) instruments based on the International Classification of Functioning, Disability and Health (ICF). Qual Life Res. 2005, 14: 1225-1237. 10.1007/s11136-004-4773-0.CrossRefPubMed Cieza A, Stucki G: Content comparison of Health Related Quality of Life (HRQOL) instruments based on the International Classification of Functioning, Disability and Health (ICF). Qual Life Res. 2005, 14: 1225-1237. 10.1007/s11136-004-4773-0.CrossRefPubMed
24.
go back to reference Chwastiak LA, Von Korff M: Disability in depression and back pain Evaluation of the World Health Organization Disability Assessment Schedule (WHO DAS II) in a primary care setting. J Clin Epidemiol. 2003, 56: 507-514. 10.1016/S0895-4356(03)00051-9.CrossRefPubMed Chwastiak LA, Von Korff M: Disability in depression and back pain Evaluation of the World Health Organization Disability Assessment Schedule (WHO DAS II) in a primary care setting. J Clin Epidemiol. 2003, 56: 507-514. 10.1016/S0895-4356(03)00051-9.CrossRefPubMed
25.
go back to reference Leonardi A, Raggi A, Bussone G, D’Amico D: Health-related quality of life, disability and severity of disease in patients with migraine attending to a Specialty Headache Center. Headache. 2010, 50 (10): 1576-1586. 10.1111/j.1526-4610.2010.01770.x.CrossRefPubMed Leonardi A, Raggi A, Bussone G, D’Amico D: Health-related quality of life, disability and severity of disease in patients with migraine attending to a Specialty Headache Center. Headache. 2010, 50 (10): 1576-1586. 10.1111/j.1526-4610.2010.01770.x.CrossRefPubMed
26.
go back to reference Bickenbach JE, Chatterji S, Badley EM, Ustün TB: Models of disablement, universalism and the international classification of impairments, disabilities and handicaps. Soc Sci Med. 1999, 48 (9): 1173-1187. 10.1016/S0277-9536(98)00441-9.CrossRefPubMed Bickenbach JE, Chatterji S, Badley EM, Ustün TB: Models of disablement, universalism and the international classification of impairments, disabilities and handicaps. Soc Sci Med. 1999, 48 (9): 1173-1187. 10.1016/S0277-9536(98)00441-9.CrossRefPubMed
27.
go back to reference Pescosolido BA, Martin JK, Long JS, Medina TR, Phelan JC, Link BG: “A disease like any other"? A decade of change in public reactions to schizophrenia, depression, and alcohol dependence. Am J Psychiatry. 2010, 167 (11): 1321-1330. 10.1176/appi.ajp.2010.09121743.CrossRefPubMedPubMedCentral Pescosolido BA, Martin JK, Long JS, Medina TR, Phelan JC, Link BG: “A disease like any other"? A decade of change in public reactions to schizophrenia, depression, and alcohol dependence. Am J Psychiatry. 2010, 167 (11): 1321-1330. 10.1176/appi.ajp.2010.09121743.CrossRefPubMedPubMedCentral
28.
go back to reference Rose D, Thornicroft G: Service user perspectives on the impact of a mental illness diagnosis. Epidemiol Psichiatr Soc. 2010, 19 (2): 140-147.CrossRefPubMed Rose D, Thornicroft G: Service user perspectives on the impact of a mental illness diagnosis. Epidemiol Psichiatr Soc. 2010, 19 (2): 140-147.CrossRefPubMed
29.
go back to reference Corrigan PW, Wassel A: Understanding and influencing the stigma of mental illness. J Psychosoc Nurs Ment Health Serv. 2008, 46 (1): 42-48. 10.3928/02793695-20080101-04.CrossRefPubMed Corrigan PW, Wassel A: Understanding and influencing the stigma of mental illness. J Psychosoc Nurs Ment Health Serv. 2008, 46 (1): 42-48. 10.3928/02793695-20080101-04.CrossRefPubMed
30.
go back to reference Rao D, Choi SW, Victorson D, Bode R, Peterman A, Heinemann A, Cella D: Measuring stigma across neurological conditions: the development of the stigma scale for chronic illness (SSCI). Qual Life Res. 2009, 18 (5): 585-595. 10.1007/s11136-009-9475-1.CrossRefPubMedPubMedCentral Rao D, Choi SW, Victorson D, Bode R, Peterman A, Heinemann A, Cella D: Measuring stigma across neurological conditions: the development of the stigma scale for chronic illness (SSCI). Qual Life Res. 2009, 18 (5): 585-595. 10.1007/s11136-009-9475-1.CrossRefPubMedPubMedCentral
31.
go back to reference Killeen MB, O'Day BL: Challenging expectations: how individuals with psychiatric disabilities find and keep work. Psychiatr Rehabil J. 2004, 28 (2): 157-163.CrossRefPubMed Killeen MB, O'Day BL: Challenging expectations: how individuals with psychiatric disabilities find and keep work. Psychiatr Rehabil J. 2004, 28 (2): 157-163.CrossRefPubMed
32.
go back to reference Dunn EC, Wewiorski NJ, Rogers ES: A qualitative investigation of individual and contextual factors associated with vocational recovery among people with serious mental illness. Am J Orthopsychiatry. 2010, 80 (2): 185-194. 10.1111/j.1939-0025.2010.01022.x.CrossRefPubMed Dunn EC, Wewiorski NJ, Rogers ES: A qualitative investigation of individual and contextual factors associated with vocational recovery among people with serious mental illness. Am J Orthopsychiatry. 2010, 80 (2): 185-194. 10.1111/j.1939-0025.2010.01022.x.CrossRefPubMed
Metadata
Title
The psychosocial difficulties in brain disorders that explain short term changes in health outcomes
Authors
Alarcos Cieza
Cristina Bostan
Jose Luis Ayuso-Mateos
Cornelia Oberhauser
Jerome Bickenbach
Alberto Raggi
Matilde Leonardi
Eduard Vieta
Somnath Chatterji
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2013
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/1471-244X-13-78

Other articles of this Issue 1/2013

BMC Psychiatry 1/2013 Go to the issue