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Published in: BMC Psychiatry 1/2011

Open Access 01-12-2011 | Research article

Treating postnatal depressive symptoms in primary care: a randomised controlled trial of GP management, with and without adjunctive counselling

Authors: Jeannette Milgrom, Christopher J Holt, Alan W Gemmill, Jennifer Ericksen, Bronwyn Leigh, Anne Buist, Charlene Schembri

Published in: BMC Psychiatry | Issue 1/2011

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Abstract

Background

Postnatal depression (PND) is under-diagnosed and most women do not access effective help. We aimed to evaluate comparative management of (PND) following screening with the Edinburgh Postnatal Depression Scale, using three best-practice care pathways by comparing management by general practitioners (GPs) alone compared to adjunctive counselling, based on cognitive behavioural therapy (CBT), delivered by postnatal nurses or psychologists.

Methods

This was a parallel, three-group randomised controlled trial conducted in a primary care setting (general practices and maternal & child health centres) and a psychology clinic. A total of 3,531 postnatal women were screened for symptoms of depression; 333 scored above cut-off on the screening tool and 169 were referred to the study. Sixty-eight of these women were randomised between the three treatment groups.

Results

Mean scores on the Beck Depression Inventory (BDI-II) at entry were in the moderate-to-severe range. There was significant variation in the post-study frequency of scores exceeding the threshold indicative of mild-to-severe depressive symptoms, such that more women receiving only GP management remained above the cut-off score after treatment (p = .028). However, all three treatment conditions were accompanied by significant reductions in depressive symptoms and mean post-study BDI-II scores were similar between groups. Compliance was high in all three groups. Women rated the treatments as highly effective. Rates of both referral to the study (51%), and subsequent treatment uptake (40%) were low.

Conclusions

Data from this small study suggest that GP management of PND when augmented by a CBT-counselling package may be successful in reducing depressive symptoms in more patients compared to GP management alone. The relatively low rates of referral and treatment uptake, suggest that help-seeking remains an issue for many women with PND, consistent with previous research.

Trial Registration

The study is registered at ClinicalTrials.gov, Trial Registration Number NCT01002027.
Appendix
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Metadata
Title
Treating postnatal depressive symptoms in primary care: a randomised controlled trial of GP management, with and without adjunctive counselling
Authors
Jeannette Milgrom
Christopher J Holt
Alan W Gemmill
Jennifer Ericksen
Bronwyn Leigh
Anne Buist
Charlene Schembri
Publication date
01-12-2011
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2011
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/1471-244X-11-95

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