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Published in: BMC Psychiatry 1/2011

Open Access 01-12-2011 | Research article

Cognitive behaviour therapy in medication-treated adults with ADHD and persistent Symptoms: A randomized controlled trial

Authors: Brynjar Emilsson, Gisli Gudjonsson, Jon F Sigurdsson, Gisli Baldursson, Emil Einarsson, Halldora Olafsdottir, Susan Young

Published in: BMC Psychiatry | Issue 1/2011

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Abstract

Background

Attention deficit hyperactivity disorder (ADHD) in adulthood is not fully treated by psychopharmacological treatment alone. The main aim of the current study was to evaluate a newly developed cognitive behaviour therapy (CBT) based group programme, the Reasoning and Rehabilitation for ADHD Youths and Adults (R&R2ADHD), using a randomized controlled trial.

Methods

54 adults with ADHD already receiving psychopharmacological treatment were randomly allocated to an experimental (CBT/MED) treatment condition (n = 27) and a 'treatment as usual' (TAU/MED) control condition (n = 27) that did not receive the CBT intervention. The outcome measures were obtained before treatment (baseline), after treatment and at three month follow-up and included ADHD symptoms and impairments rated by independent assessors, self-reported current ADHD symptoms, and comorbid problems.

Results

The findings suggested medium to large treatment effects for ADHD symptoms, which increased further at three month follow-up. Additionally, comorbid problems also improved at follow-up with large effect sizes.

Conclusions

The findings give support for the effectiveness of R&R2ADHD in reducing ADHD symptoms and comorbid problems, an improving functions associated with impairment. The implications are that the benefits of R&R2ADHD are multifaceted and that combined psychopharmacological and CBT based treatments may add to and improve pharmacological interventions.
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Literature
1.
go back to reference Barkley RA, Murphy KR, Fischer M: ADHD in adults: What the science says. 2008, New York: The Guilford Press Barkley RA, Murphy KR, Fischer M: ADHD in adults: What the science says. 2008, New York: The Guilford Press
2.
go back to reference Kessler RC, Adler L, Barkley R, Biederman J, Conners CK, Demler O, Faraone SV, Greenhill LL, Howes MJ, Secnik K, Spencer T, Ustun TB, Walters EE, Zaslavsky AM: The prevalence and correlates of adult ADHD in the United States: Results from the National Comorbidity Survey Replication. American Journal of Psychiatry. 2006, 163 (Suppl 4): 716-23.CrossRefPubMedPubMedCentral Kessler RC, Adler L, Barkley R, Biederman J, Conners CK, Demler O, Faraone SV, Greenhill LL, Howes MJ, Secnik K, Spencer T, Ustun TB, Walters EE, Zaslavsky AM: The prevalence and correlates of adult ADHD in the United States: Results from the National Comorbidity Survey Replication. American Journal of Psychiatry. 2006, 163 (Suppl 4): 716-23.CrossRefPubMedPubMedCentral
3.
go back to reference Young S, Gudjonsson GH, Wells J, Asherson P, Theobald D, Oliver B, Scott C, Mooney A: Attention Deficit Hyperactivity Disorder and critical incidents in a Scottish prison population. Personality and Individual Difference. 2009, 46: 265-269. 10.1016/j.paid.2008.10.003.CrossRef Young S, Gudjonsson GH, Wells J, Asherson P, Theobald D, Oliver B, Scott C, Mooney A: Attention Deficit Hyperactivity Disorder and critical incidents in a Scottish prison population. Personality and Individual Difference. 2009, 46: 265-269. 10.1016/j.paid.2008.10.003.CrossRef
4.
go back to reference Young S, Wells J, Gudjonsson GH: Predictors of offending among prisoners. The role of Attention Deficit Hyperactivity Disorder (ADHD) and substance use. Journal of Psychopharmacology. Published Online First: 17 June 2010, Young S, Wells J, Gudjonsson GH: Predictors of offending among prisoners. The role of Attention Deficit Hyperactivity Disorder (ADHD) and substance use. Journal of Psychopharmacology. Published Online First: 17 June 2010,
5.
go back to reference Simon V, Czobor P, Balint S, Meszaros A, Bitter I: Prevalence and correlates of adult attention-deficit hyperactivity disorder: Meta-analysis. British Journal of Psychiatry. 2009, 194 (Suppl 3): 204-211.CrossRefPubMed Simon V, Czobor P, Balint S, Meszaros A, Bitter I: Prevalence and correlates of adult attention-deficit hyperactivity disorder: Meta-analysis. British Journal of Psychiatry. 2009, 194 (Suppl 3): 204-211.CrossRefPubMed
6.
go back to reference Dalsgaard S, Mortensen PB, Frydenberg M, Thomsen PH: Conduct problems, gender and adult psychiatric outcome of children with attention-deficit hyperactivity disorder. British Journal of Psychiatry. 2003, 181: 416-421.CrossRef Dalsgaard S, Mortensen PB, Frydenberg M, Thomsen PH: Conduct problems, gender and adult psychiatric outcome of children with attention-deficit hyperactivity disorder. British Journal of Psychiatry. 2003, 181: 416-421.CrossRef
7.
go back to reference Langley K, Fowler T, Ford T, Thapar AK, van den Bree M, Harold G, Owen MJ, O'Donovan MC, Thapar A: Adolescent clinical outcomes for young people with attention-deficit hyperactivity disorder. The British Journal of Psychiatry. 2010, 196: 235-240. 10.1192/bjp.bp.109.066274.CrossRefPubMed Langley K, Fowler T, Ford T, Thapar AK, van den Bree M, Harold G, Owen MJ, O'Donovan MC, Thapar A: Adolescent clinical outcomes for young people with attention-deficit hyperactivity disorder. The British Journal of Psychiatry. 2010, 196: 235-240. 10.1192/bjp.bp.109.066274.CrossRefPubMed
8.
go back to reference National Institute for Health and Clinical Excellence: Attention deficit hyperactivity disorder: Diagnosis and management of ADHD in children, young people and adults. 2009, London: The British Psychological Society and the Royal College of Psychiatrists National Institute for Health and Clinical Excellence: Attention deficit hyperactivity disorder: Diagnosis and management of ADHD in children, young people and adults. 2009, London: The British Psychological Society and the Royal College of Psychiatrists
9.
go back to reference Gudjonsson GH, Wells J, Young S: Personality disorders and clinical syndromes in ADHD prisoners. Journal of Attention Disorders. Gudjonsson GH, Wells J, Young S: Personality disorders and clinical syndromes in ADHD prisoners. Journal of Attention Disorders.
10.
go back to reference Young S: Coping Strategies used by ADHD adults. Personality and Individual Differences. 2005, 38 (Suppl 4): 809-816.CrossRef Young S: Coping Strategies used by ADHD adults. Personality and Individual Differences. 2005, 38 (Suppl 4): 809-816.CrossRef
11.
go back to reference Gudjonsson GH, Sigurdsson JF, Eyjolfsdottir GA, Smari J, Young S: The relationship between satisfaction with life, ADHD symptoms and associated problems among university students. Journal of Attention Disorders. 2009, 12: 507-515.CrossRefPubMed Gudjonsson GH, Sigurdsson JF, Eyjolfsdottir GA, Smari J, Young S: The relationship between satisfaction with life, ADHD symptoms and associated problems among university students. Journal of Attention Disorders. 2009, 12: 507-515.CrossRefPubMed
12.
go back to reference Kooij SJ, Bejerot S, Blackwell A, Caci H, Casas-Brugué M, Carpentier PJ, Edvinsson D, Fayyad J, Foeken K, Fitzgerald M, Gaillac V, Ginsberg Y, Henry C, Krause J, Lensing MB, Manor I, Niederhofer H, Nunes-Filipe C, Ohlmeier MD, Oswald P, Pallanti S, Pehlivanidis A, Ramos-Quiroga JA, Rastam M, Ryffel-Rawak D, Stes S, Asherson P: European consensus statement on diagnosis and treatment of adult ADHD: The European Network Adult ADHD. BMC Psychiatry. 2010, 3 (Suppl 10): 67-CrossRef Kooij SJ, Bejerot S, Blackwell A, Caci H, Casas-Brugué M, Carpentier PJ, Edvinsson D, Fayyad J, Foeken K, Fitzgerald M, Gaillac V, Ginsberg Y, Henry C, Krause J, Lensing MB, Manor I, Niederhofer H, Nunes-Filipe C, Ohlmeier MD, Oswald P, Pallanti S, Pehlivanidis A, Ramos-Quiroga JA, Rastam M, Ryffel-Rawak D, Stes S, Asherson P: European consensus statement on diagnosis and treatment of adult ADHD: The European Network Adult ADHD. BMC Psychiatry. 2010, 3 (Suppl 10): 67-CrossRef
13.
go back to reference Wilens TE, Spencer TJ, Biederman J: A review of the pharmacotherapy of adults with attention-deficit/hyperactivity disorder. Journal of Attention Problems. 2002, 5 (Suppl 4): 189-202. Wilens TE, Spencer TJ, Biederman J: A review of the pharmacotherapy of adults with attention-deficit/hyperactivity disorder. Journal of Attention Problems. 2002, 5 (Suppl 4): 189-202.
14.
go back to reference McCarthy S, Asherson P, Coghill D, Hollis C, Murray M, Potts L, Sayal K, de Soysa R, Taylor E, Williams T, Wong IC: Attention-deficit hyperactivity disorder. Treatment discontinuation in adolescents and young adults. British Journal of Psychiatry. 2009, 194 (Suppl 3): 273-277.CrossRefPubMed McCarthy S, Asherson P, Coghill D, Hollis C, Murray M, Potts L, Sayal K, de Soysa R, Taylor E, Williams T, Wong IC: Attention-deficit hyperactivity disorder. Treatment discontinuation in adolescents and young adults. British Journal of Psychiatry. 2009, 194 (Suppl 3): 273-277.CrossRefPubMed
15.
go back to reference Fayyad J, De Graaf R, Kessler R, Alonso J, Angermeyer M, Demyttenaere K, De Girolamo G, Haro JM, Karam EG, Lara C, Lépine JP, Ormel J, Posada-Villa J, Zaslavsky AM, Jin R: Cross-national prevalence and correlates of adult attention-deficit hyperactivity disorder. British Journal of Psychiatry. 2007, 190: 402-409. 10.1192/bjp.bp.106.034389.CrossRefPubMed Fayyad J, De Graaf R, Kessler R, Alonso J, Angermeyer M, Demyttenaere K, De Girolamo G, Haro JM, Karam EG, Lara C, Lépine JP, Ormel J, Posada-Villa J, Zaslavsky AM, Jin R: Cross-national prevalence and correlates of adult attention-deficit hyperactivity disorder. British Journal of Psychiatry. 2007, 190: 402-409. 10.1192/bjp.bp.106.034389.CrossRefPubMed
16.
go back to reference Safren SA, Otto MW, Sprich S, Winett CL, Wilens TE, Biederman J: Cognitive-behavioral therapy for ADHD in medication-treated adults with continued symptoms. Behaviour Research and Therapy. 2005, 43 (Suppl 7): 831-842.CrossRefPubMed Safren SA, Otto MW, Sprich S, Winett CL, Wilens TE, Biederman J: Cognitive-behavioral therapy for ADHD in medication-treated adults with continued symptoms. Behaviour Research and Therapy. 2005, 43 (Suppl 7): 831-842.CrossRefPubMed
17.
go back to reference Safren SA, Sprich S, Mimiaga MJ, Surman C, Knouse L, Groves M, Otto MW: Cognitive behavioural therapy vs relaxation with educational support for medication-treated adults with ADHD and persistent symptoms: A randomized controlled trial. The Journal of the American Medical Association. 2010, 304 (Suppl 8): 875-880.CrossRefPubMed Safren SA, Sprich S, Mimiaga MJ, Surman C, Knouse L, Groves M, Otto MW: Cognitive behavioural therapy vs relaxation with educational support for medication-treated adults with ADHD and persistent symptoms: A randomized controlled trial. The Journal of the American Medical Association. 2010, 304 (Suppl 8): 875-880.CrossRefPubMed
18.
go back to reference Virta M, Salakari A, Antila M, Chydenius E, Partinen M, Kaski M, Vataja R, Kalska H, Iivanainen M: Short cognitive behavioural therapy and cognitive training for adults with ADHD - a randomized controlled pilot study. Neuropsychiatric Disease and Treatment. 2010, 7 (Suppl 6): 443-53.CrossRef Virta M, Salakari A, Antila M, Chydenius E, Partinen M, Kaski M, Vataja R, Kalska H, Iivanainen M: Short cognitive behavioural therapy and cognitive training for adults with ADHD - a randomized controlled pilot study. Neuropsychiatric Disease and Treatment. 2010, 7 (Suppl 6): 443-53.CrossRef
19.
go back to reference Solanto MV, Marks DJ, Wasserstein J, Mitchell K, Abikoff H, Alvir JM, Kofman MD: Efficacy of meta-cognitive therapy for adult ADHD. The American Journal of Psychiatry. 2010, 167 (Suppl 8): 958-968.CrossRefPubMedPubMedCentral Solanto MV, Marks DJ, Wasserstein J, Mitchell K, Abikoff H, Alvir JM, Kofman MD: Efficacy of meta-cognitive therapy for adult ADHD. The American Journal of Psychiatry. 2010, 167 (Suppl 8): 958-968.CrossRefPubMedPubMedCentral
20.
go back to reference Hirvikoski T, Waaler E, Alfredsson J, Pihlgren C, Holmström A, Johnson A, Rück J, Wiwe C, Bothén P, Nordström AL: Reduced ADHD symptoms in adults with ADHD after structured skills training group: Results from a randomized controlled trial. Behavior Research and Therapy. 2011, 49 (Suppl 3): 175-85.CrossRef Hirvikoski T, Waaler E, Alfredsson J, Pihlgren C, Holmström A, Johnson A, Rück J, Wiwe C, Bothén P, Nordström AL: Reduced ADHD symptoms in adults with ADHD after structured skills training group: Results from a randomized controlled trial. Behavior Research and Therapy. 2011, 49 (Suppl 3): 175-85.CrossRef
21.
go back to reference Stevenson CS, Whitmont S, Bornholt L, Livesey D, Stevenson RJ: A cognitive remediation programme for adults with attention deficit hyperactivity disorder. Australian and New Zealand Journal of Psychiatry. 2002, 36 (Suppl 5): 610-616.CrossRefPubMed Stevenson CS, Whitmont S, Bornholt L, Livesey D, Stevenson RJ: A cognitive remediation programme for adults with attention deficit hyperactivity disorder. Australian and New Zealand Journal of Psychiatry. 2002, 36 (Suppl 5): 610-616.CrossRefPubMed
22.
go back to reference Bramham J, Young S, Bickerdike A, Spain D, McCarten D, Xenitidis K: Evaluation of group cognitive behavioural therapy for adults with ADHD. Journal of Attention Disorders. 2009, 12 (Suppl 5): 434-441.CrossRefPubMed Bramham J, Young S, Bickerdike A, Spain D, McCarten D, Xenitidis K: Evaluation of group cognitive behavioural therapy for adults with ADHD. Journal of Attention Disorders. 2009, 12 (Suppl 5): 434-441.CrossRefPubMed
23.
go back to reference Young S, Bramham J: ADHD in Adults: A Psychological Guide to Practice. 2007, Chichester: John Wiley & Sons Young S, Bramham J: ADHD in Adults: A Psychological Guide to Practice. 2007, Chichester: John Wiley & Sons
24.
go back to reference Young S, Toone B, Tyson C: Comorbidity and psychosocial profile of adults with Attention Deficit Hyperactivity Disorder. Personality and Individual Differences. 2003, 35: 743-755. 10.1016/S0191-8869(02)00267-2.CrossRef Young S, Toone B, Tyson C: Comorbidity and psychosocial profile of adults with Attention Deficit Hyperactivity Disorder. Personality and Individual Differences. 2003, 35: 743-755. 10.1016/S0191-8869(02)00267-2.CrossRef
25.
go back to reference Kaufman J, Birmaher B, Brent D, Rao U, Ryan N: Kiddie-SADS-Present and Lifetime Version(K-SADS-PL). 1996, Pittsburgh, Penn: The Department of Psychiatry, University of Pittsburgh School of Medicine Kaufman J, Birmaher B, Brent D, Rao U, Ryan N: Kiddie-SADS-Present and Lifetime Version(K-SADS-PL). 1996, Pittsburgh, Penn: The Department of Psychiatry, University of Pittsburgh School of Medicine
26.
go back to reference Magnusson P, Smari J, Sigurdardottir D, Baldursson G, Sigmundsson J, Kristjansson K, Sigurdardottir S, Hreidarsson S, Sigurbjornsdottir S, Gudmundsson OO: Validity of self-report and informant rating scales of adult ADHD symptoms in comparison with a semistructured diagnostic interview. Journal of Attention disorders. 2006, 9 (Suppl 3): 494-503.CrossRefPubMed Magnusson P, Smari J, Sigurdardottir D, Baldursson G, Sigmundsson J, Kristjansson K, Sigurdardottir S, Hreidarsson S, Sigurbjornsdottir S, Gudmundsson OO: Validity of self-report and informant rating scales of adult ADHD symptoms in comparison with a semistructured diagnostic interview. Journal of Attention disorders. 2006, 9 (Suppl 3): 494-503.CrossRefPubMed
27.
go back to reference National Institute of Mental Health: CGI Clinical Global Impression Scale-NIMH. Psychopharmacology Bulletin. 1985, 21: 839-844. National Institute of Mental Health: CGI Clinical Global Impression Scale-NIMH. Psychopharmacology Bulletin. 1985, 21: 839-844.
28.
go back to reference Spencer TJ, Adler LA, Meihua Qiao, Saylor KE, Brown TE, Holdnack JA, Schuh KJ, Trzepacz PT, Kelsey DK: Validation of the Adult ADHD Investigator Symptom Rating Scale (AISRS). Journal of Attention Disorders. 2010, 14 (Suppl 1): 57-68.CrossRefPubMed Spencer TJ, Adler LA, Meihua Qiao, Saylor KE, Brown TE, Holdnack JA, Schuh KJ, Trzepacz PT, Kelsey DK: Validation of the Adult ADHD Investigator Symptom Rating Scale (AISRS). Journal of Attention Disorders. 2010, 14 (Suppl 1): 57-68.CrossRefPubMed
29.
go back to reference Zhang S, Faries DE, Vowles M, Michelson D: ADHD rating scale IV: psychometric properties from a multinational study as clinician-administered instrument. International Journal of Methods in Psychiatric Research. 2005, 14 (Suppl 4): 186-201.CrossRefPubMed Zhang S, Faries DE, Vowles M, Michelson D: ADHD rating scale IV: psychometric properties from a multinational study as clinician-administered instrument. International Journal of Methods in Psychiatric Research. 2005, 14 (Suppl 4): 186-201.CrossRefPubMed
30.
go back to reference Barkley RA: Attention deficit/hyperactivity disorder: A handbook for diagnosis and treatment. 1998, New York; Guilford Press, 2 Barkley RA: Attention deficit/hyperactivity disorder: A handbook for diagnosis and treatment. 1998, New York; Guilford Press, 2
31.
go back to reference Beck AT, Steer RA: Beck Anxiety Inventory Manual. 1993, San Antonio: The Psychological Corporation Beck AT, Steer RA: Beck Anxiety Inventory Manual. 1993, San Antonio: The Psychological Corporation
32.
go back to reference Beck AT, Ward C, Mendelson M: Beck Depression Inventory (BDI). Archives of General Psychiatry. 1961, 4: 561-571.CrossRefPubMed Beck AT, Ward C, Mendelson M: Beck Depression Inventory (BDI). Archives of General Psychiatry. 1961, 4: 561-571.CrossRefPubMed
33.
go back to reference Young S, Ross RR: R&R2 ADHD for Youths and Adults: A Prosocial Training Program. 2007, Ottawa: Cognitive Centre of Canada Young S, Ross RR: R&R2 ADHD for Youths and Adults: A Prosocial Training Program. 2007, Ottawa: Cognitive Centre of Canada
34.
go back to reference Gudjonsson GH, Sigurdsson JF, Gudmundsdottir HB, Sigurjonsdottir S: The relationship between ADHD symptoms in college students and core components of maladaptive personality. Personality and Individual Differences. 2010, 48: 601-606. 10.1016/j.paid.2009.12.015.CrossRef Gudjonsson GH, Sigurdsson JF, Gudmundsdottir HB, Sigurjonsdottir S: The relationship between ADHD symptoms in college students and core components of maladaptive personality. Personality and Individual Differences. 2010, 48: 601-606. 10.1016/j.paid.2009.12.015.CrossRef
35.
go back to reference Ross RR, Fabiano EA: Time to think: A cognitive model of delinquency prevention and offender rehabilitation. 1985, Johnson City, TN: Institute of Social Sciences and Arts Ross RR, Fabiano EA: Time to think: A cognitive model of delinquency prevention and offender rehabilitation. 1985, Johnson City, TN: Institute of Social Sciences and Arts
36.
go back to reference Clarke AY, Cullen AE, Walwyn R, Fahy T: A quasi-experimental pilot study of the Reasoning and Rehabilitation programme with mentally disordered offenders. The Journal of Forensic Psychiatry and Psychology. 2010, 21: 490-500. 10.1080/14789940903236391.CrossRef Clarke AY, Cullen AE, Walwyn R, Fahy T: A quasi-experimental pilot study of the Reasoning and Rehabilitation programme with mentally disordered offenders. The Journal of Forensic Psychiatry and Psychology. 2010, 21: 490-500. 10.1080/14789940903236391.CrossRef
37.
go back to reference Tong LS, Farrington DP: How effective is the "Reasoning and Rehabilitation" programme in reducing reoffending? A meta-analysis of evaluations in four countries. Psychology, Crime and Law. 2006, 12 (Suppl 1): 3-24.CrossRef Tong LS, Farrington DP: How effective is the "Reasoning and Rehabilitation" programme in reducing reoffending? A meta-analysis of evaluations in four countries. Psychology, Crime and Law. 2006, 12 (Suppl 1): 3-24.CrossRef
38.
go back to reference Young S, Gudjonsson G, Chick K: A preliminary Evaluation of Reasoning and Rehabilitation 2 in Mentally Disordered Offenders (R&R2M) Across Two Secure Forensic Settings in the United Kingdom. Journal of Forensic Psychiatry and Psychology. 2010, 21 (Suppl 3): 336-349.CrossRef Young S, Gudjonsson G, Chick K: A preliminary Evaluation of Reasoning and Rehabilitation 2 in Mentally Disordered Offenders (R&R2M) Across Two Secure Forensic Settings in the United Kingdom. Journal of Forensic Psychiatry and Psychology. 2010, 21 (Suppl 3): 336-349.CrossRef
Metadata
Title
Cognitive behaviour therapy in medication-treated adults with ADHD and persistent Symptoms: A randomized controlled trial
Authors
Brynjar Emilsson
Gisli Gudjonsson
Jon F Sigurdsson
Gisli Baldursson
Emil Einarsson
Halldora Olafsdottir
Susan Young
Publication date
01-12-2011
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2011
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/1471-244X-11-116

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