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BMC Ophthalmology
Published in: BMC Ophthalmology 1/2014

Open Access 01-12-2014 | Study protocol

The Nakuru eye disease cohort study: methodology & rationale

Authors: Andrew Bastawrous, Wanjiku Mathenge, Tunde Peto, Helen A Weiss, Hillary Rono, Allen Foster, Matthew Burton, Hannah Kuper

Published in: BMC Ophthalmology | Issue 1/2014

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Abstract

Background

No longitudinal data from population-based studies of eye disease in sub-Saharan-Africa are available. A population-based survey was undertaken in 2007/08 to estimate the prevalence and determinants of blindness and low vision in Nakuru district, Kenya. This survey formed the baseline to a six-year prospective cohort study to estimate the incidence and progression of eye disease in this population.

Methods/Design

A nationally representative sample of persons aged 50 years and above were selected between January 2007 and November 2008 through probability proportionate to size sampling of clusters, with sampling of individuals within clusters through compact segment sampling. Selected participants underwent detailed ophthalmic examinations which included: visual acuity, autorefraction, visual fields, slit lamp assessment of the anterior and posterior segments, lens grading and fundus photography. In addition, anthropometric measures were taken and risk factors were assessed through structured interviews. Six years later (2013/2014) all subjects were invited for follow-up assessment, repeating the baseline examination methodology.

Discussion

The methodology will provide estimates of the progression of eye diseases and incidence of blindness, visual impairment, and eye diseases in an adult Kenyan population.
Appendix
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Metadata
Title
The Nakuru eye disease cohort study: methodology & rationale
Authors
Andrew Bastawrous
Wanjiku Mathenge
Tunde Peto
Helen A Weiss
Hillary Rono
Allen Foster
Matthew Burton
Hannah Kuper
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Ophthalmology / Issue 1/2014
Electronic ISSN: 1471-2415
DOI
https://doi.org/10.1186/1471-2415-14-60

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