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Open Access 01-12-2009 | Case report

Case report: Malignant teratoma of the uterine corpus

Authors: Thomas Newsom-Davis, Daniel Poulter, Rebecca Gray, Mohammed Ameen, Iain Lindsay, Kyriakos Papanikolaou, Simon Butler-Manuel, Timothy Christmas, Peter Townsend, Michael Seckl

Published in: BMC Cancer | Issue 1/2009

Abstract

Background

Teratomas are the commonest germ cell tumours and are most frequently found in the testes and ovary. Extragonadal teratomas are rare and mainly occur in midline structures. Uterine teratomas are extremely rare with only a few previous case reports, usually involving mature teratomas of the uterine cervix.

Case Presentation

We report an 82-year-old lady presenting with post-menopausal bleeding. Initial investigations revealed a benign teratoma of the uterus which was removed. Her symptoms persisted and a recurrent, now malignant, teratoma of the uterine corpus was resected at hysterectomy. Six months after surgery she relapsed with para-aortic lymphadenopathy and was treated with a taxane, etoposide and cisplatin-containing chemotherapy regimen followed by retroperitoneal lymph node dissection.

Conclusion

In this report we discuss the aetiology, diagnosis and management of uterine teratomas, and review previous case studies.

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The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2407/9/195/prepub

Title: Case report: Malignant teratoma of the uterine corpus
Authors: Thomas Newsom-Davis
Daniel Poulter
Rebecca Gray
Mohammed Ameen
Iain Lindsay
Kyriakos Papanikolaou
Simon Butler-Manuel
Timothy Christmas
Peter Townsend
Michael Seckl
Publication date: 01-12-2009
Publisher: BioMed Central
Published in: BMC Cancer / Issue 1/2009
Electronic ISSN: 1471-2407
DOI: https://doi.org/10.1186/1471-2407-9-195

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Abstract

Background

Case Presentation

Conclusion

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