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BMC Cancer
Published in: BMC Cancer 1/2011

Open Access 01-12-2011 | Research article

Fish consumption and the risk of gastric cancer: systematic review and meta-analysis

Authors: Shengjun Wu, Jie Liang, Lei Zhang, Xia Zhu, Xufeng Liu, Danmin Miao

Published in: BMC Cancer | Issue 1/2011

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Abstract

Background

Gastric cancer is the fourth most frequently occurring malignancy after lung, breast, and colorectal cancer, and the second most common cause of death from cancer worldwide. Epidemiologic studies have examined the possible association between fish consumption and gastric cancer, but the results were inconclusive. We conducted a systematic review and meta-analysis to examine the association between fish intake and the risk of gastric cancer.

Methods

PubMed was searched for studies published in English-language journals from 1991 through 2009. We identified 17 epidemiologic studies (15 case-control and 2 cohort studies) that included relative risks (RRs) or odds ratios (ORs) estimates with 95% confidence intervals (CIs) of the relationship between gastric cancer and fish consumption. Data were extracted using standardized data forms. Summary RRs or ORs for the highest versus non/lowest fish consumption levels were calculated using random-effects model. Heterogeneity among studies was examined using Q and I2 statistics.

Results

In this study, 5,323 cases of gastric cancer and over 130,000 non-cases were included. The combined results from all studies indicated that the association between high fish consumption and reduced gastric cancer risk was not statistically insignificant (RR = 0.87, 95% CI = 0.71-1.07).

Conclusions

Current evidence indicated that the association between fish consumption and risk of gastric cancer remains unclear.
Appendix
Available only for authorised users
Literature
1.
Parkin DM, Bray F, Ferlay J, Pisani P: Global cancer statistics, 2002. CA Cancer J Clin. 2005, 55: 74-108. 10.3322/canjclin.55.2.74.CrossRefPubMed
2.
Brenner H, Rothenbacher D, Arndt V: Epidemiology of stomach cancer. Methods Mol Biol. 2009, 472: 467-477. full_text.CrossRefPubMed
3.
Nomura A: Stomach cancer. Cancer epidemiology and prevention. Edited by: Schottenfeld D, Fraumeni J. 1996, New York, Oxford University Press, 707-724.
4.
Riboli E, Norat T: Cancer prevention and diet: opportunities in Europe. Public Health Nutr. 2001, 4 (2B): 475-484. 10.1079/PHN2001158.CrossRefPubMed
5.
Key TJ, Schatzkin A, Willett WC, Allen NE, Spencer EA, Travis RC: Diet, nutrition and the prevention of cancer. Public Health Nutr. 2004, 7 (1A): 187-200. 10.1079/PHN2003588.CrossRefPubMed
6.
Gonzalez CA: Nutrition and cancer: the current epidemiological evidence. Br J Nutr. 2006, 96 (Suppl 1): 42-45. 10.1079/BJN20061699.CrossRef
7.
Wiseman M: The second World Cancer Research Fund/American Institute for Cancer Research expert report. Food, nutrition, physical activity, and the prevention of cancer: a global perspective. Proc Nutr Soc. 2008, 67: 253-256. 10.1017/S002966510800712X.CrossRefPubMed
8.
Simopoulos AP: Omega-3 fatty acids in health and disease and in growth and development. Am J Clin Nutr. 1991, 54: 438-463.PubMed
9.
Fernandez E, Chatenoud L, La Vecchia C, Negri E, Franceschi S: Fish consumption and cancer risk. Am J Clin Nutr. 1999, 70: 85-90.PubMed
10.
Karmali RA: n-3 Fatty acids and cancer. J Intern Med Suppl. 1989, 225: 197-200.CrossRef
11.
Rose DP, Connolly JM: Omega-3 fatty acids as cancer chemopreventive agents. Pharmacol Ther. 1999, 83: 217-244. 10.1016/S0163-7258(99)00026-1.CrossRefPubMed
12.
Buiatti E, Palli D, Bianchi S, Decarli A, Amadori D, Avellini C, Cipriani F, Cocco P, Giacosa A, Lorenzini L, Marubini E, Puntoni R, Saragoni A, Fraumeni JF, Blot WJ: A case-control study of gastric cancer and diet in Italy. III. Risk patterns by histologic type. Int J Cancer. 1991, 48: 369-374. 10.1002/ijc.2910480310.CrossRefPubMed
13.
Chen H, Ward MH, Graubard BI, Heineman EF, Markin RM, Potischman NA, Russell RM, Weisenburger DD, Tucker KL: Dietary patterns and adenocarcinoma of the esophagus and distal stomach. Am J Clin Nutr. 2002, 75: 137-144.PubMed
14.
Cornée J, Pobel D, Riboli E, Guyader M, Hémon B: A case-control study of gastric cancer and nutritional factors in Marseille, France. Eur J Epidemiol. 1995, 11: 55-65.CrossRefPubMed
15.
De Stefani E, Correa P, Boffetta P, Deneo-Pellegrini H, Ronco AL, Mendilaharsu M: Dietary patterns and risk of gastric cancer: a case-control study in Uruguay. Gastric Cancer. 2004, 7: 211-220. 10.1007/s10120-004-0295-2.CrossRefPubMed
16.
Fernandez E, Chatenoud L, La Vecchia C, Negri E, Franceschi S: Fish consumption and cancer risk. Am J Clin Nutr. 1999, 70: 85-90.PubMed
17.
Hamada GS, Kowalski LP, Nishimoto IN, Rodrigues JJ, Iriya K, Sasazuki S, Hanaoka T, Tsugane S, São Paulo--Japan Cancer Project Gastric Cancer Study Group: Risk factors for stomach cancer in Brazil (II): a case-control study among Japanese Brazilians in São Paulo. Jpn J Clin Oncol. 2002, 32: 284-290. 10.1093/jjco/hyf061.CrossRefPubMed
18.
Hoshiyama Y, Sasaba T: A case-control study of single and multiple stomach cancers in Saitama Prefecture, Japan. Jpn J Cancer Res. 1992, 83: 937-943.CrossRefPubMed
19.
Hu J, La Vecchia C, DesMeules M, Negri E, Mery L, Canadian Cancer Registries Epidemiology Research Group: Meat and fish consumption and cancer in Canada. Nutr Cancer. 2008, 60: 313-324. 10.1080/01635580701759724.CrossRefPubMed
20.
Muñoz N, Plummer M, Vivas J, Moreno V, De Sanjosé S, Lopez G, Oliver W: A case-control study of gastric cancer in Venezuela. Int J Cancer. 2001, 93: 417-423.CrossRefPubMed
21.
Phukan RK, Narain K, Zomawia E, Hazarika NC, Mahanta J: Dietary habits and stomach cancer in Mizoram, India. J Gastroenterol. 2006, 41: 418-424. 10.1007/s00535-006-1761-x.CrossRefPubMed
22.
Pourfarzi F, Whelan A, Kaldor J, Malekzadeh R: The role of diet and other environmental factors in the causation of gastric cancer in Iran--a population based study. Int J Cancer. 2009, 125: 1953-1960. 10.1002/ijc.24499.CrossRefPubMed
23.
Rao DN, Ganesh B, Dinshaw KA, Mohandas KM: A case-control study of stomach cancer in Mumbai, India. Int J Cancer. 2002, 99: 727-731. 10.1002/ijc.10339.CrossRefPubMed
24.
Ito LS, Inoue M, Tajima K, Yamamura Y, Kodera Y, Hirose K, Takezaki T, Hamajima N, Kuroishi T, Tominaga S: Dietary factors and the risk of gastric cancer among Japanese women: a comparison between the differentiated and non-differentiated subtypes. Ann Epidemiol. 2003, 13: 24-31. 10.1016/S1047-2797(02)00269-7.CrossRefPubMed
25.
Takezaki T, Gao CM, Wu JZ, Ding JH, Liu YT, Zhang Y, Li SP, Su P, Liu TK, Tajima K: Dietary protective and risk factors for esophageal and stomach cancers in a low-epidemic area for stomach cancer in Jiangsu Province, China: comparison with those in a high-epidemic area. Jpn J Cancer Res. 2001, 92: 1157-1165.CrossRefPubMed
26.
Ward MH, López-Carrillo L: Dietary factors and the risk of gastric cancer in Mexico City. Am J Epidemiol. 1999, 149: 925-932.CrossRefPubMed
27.
Larsson SC, Bergkvist L, Wolk A: Processed meat consumption, dietary nitrosamines and stomach cancer risk in a cohort of Swedish women. Int J Cancer. 2006, 119: 915-919. 10.1002/ijc.21925.CrossRefPubMed
28.
Ngoan LT, Mizoue T, Fujino Y, Tokui N, Yoshimura T: Dietary factors and stomach cancer mortality. Br J Cancer. 2002, 87: 37-42. 10.1038/sj.bjc.6600415.CrossRefPubMedPubMedCentral
29.
Key TJ, Appleby PN, Spencer EA, Travis RC, Allen NE, Thorogood M, Mann JI: Cancer incidence in British vegetarians. Br J Cancer. 2009, 101: 192-197. 10.1038/sj.bjc.6605098.CrossRefPubMedPubMedCentral
30.
DerSimonian R, Laird N: Meta-analysis in clinical trials. Control Clin Trials. 1986, 7: 177-188. 10.1016/0197-2456(86)90046-2.CrossRefPubMed
31.
32.
Hedges LV, Pigott TD: The power of statistical tests in meta-analysis. Psychol Method. 2001, 6: 203-217. 10.1037/1082-989X.6.3.203.CrossRef
33.
Thornton A, Lee P: Publication bias in meta-analysis: its causes and consequences. J Clin Epidemiol. 2000, 53: 207-216. 10.1016/S0895-4356(99)00161-4.CrossRefPubMed
34.
35.
Campbell PT, Sloan M, Kreiger N: Dietary patterns and risk of incident gastric adenocarcinoma. Am J Epidemiol. 2008, 167: 295-304. 10.1093/aje/kwm294.CrossRefPubMed
36.
Nomura AM, Hankin JH, Kolonel LN, Wilkens LR, Goodman MT, Stemmermann GN: Case-control study of diet and other risk factors for gastric cancer in Hawaii (United States). Cancer Causes Control. 2003, 14: 547-558. 10.1023/A:1024887411846.CrossRefPubMed
37.
Kim MK, Sasaki S, Sasazuki S, Tsugane S, Japan Public Health Center-based Prospective Study Group: Prospective study of three major dietary patterns and risk of gastric cancer in Japan. Int J Cancer. 2004, 110: 435-342. 10.1002/ijc.20132.CrossRefPubMed
38.
Geelen A, Schouten JM, Kamphuis C, Stam BE, Burema J, Renkema JM, Bakker EJ, van't Veer P, Kampman E: Fish consumption, n-3 fatty acids, and colorectal cancer: a meta-analysis of prospective cohort studies. Am J Epidemiol. 2007, 166: 1116-1125. 10.1093/aje/kwm197.CrossRefPubMed
39.
Lunet N, Valbuena C, Vieira AL, Lopes C, Lopes C, David L, Carneiro F, Barros H: Fruit and vegetable consumption and gastric cancer by location and histological type: case-control and meta-analysis. Eur J Cancer Prev. 2007, 16: 312-327. 10.1097/01.cej.0000236255.95769.22.CrossRefPubMed
40.
Liu CY, Hsu YH, Wu MT, Pan PC, Ho CK, Su L, Xu X, Li Y, Christiani DC, Kaohsiung Leukemia Research Group: Cured meat, vegetables, and bean-curd foods in relation to childhood acute leukemia risk: a population based case-control study. BMC Cancer. 2009, 9: 15-10.1186/1471-2407-9-15.CrossRefPubMedPubMedCentral
41.
Engeset D, Dyachenko A, Ciampi A, Lund E: Dietary patterns and risk of cancer of various sites in the Norwegian European Prospective Investigation into Cancer and Nutrition cohort: the Norwegian Women and Cancer study. Eur J Cancer Prev. 2009, 18: 69-75. 10.1097/CEJ.0b013e328305a091.CrossRefPubMed
42.
Gonzalez CA, Riboli E: Diet and cancer prevention: where we are, where we are going. Nutr Cancer. 2006, 56: 225-231. 10.1207/s15327914nc5602_14.CrossRefPubMed
43.
Kim J, Lim SY, Shin A, Sung MK, Ro J, Kang HS, Lee KS, Kim SW, Lee ES: Fatty fish and fish omega-3 fatty acid intakes decrease the breast cancer risk: a case-control study. BMC Cancer. 2009, 9: 216-10.1186/1471-2407-9-216.CrossRefPubMedPubMedCentral
44.
Pot GK, Majsak-Newman G, Geelen A, Harvey LJ, Nagengast FM, Witteman BJ, van de Meeberg PC, Timmer R, Tan A, Wahab PJ, Hart AR, Williams MP, Przybylska-Phillips K, Dainty JR, Schaafsma G, Kampman E, Lund EK, FISHGASTRO Study Group: Fish consumption and markers of colorectal cancer risk: a multicenter randomized controlled trial. Am J Clin Nutr. 2009, 90: 354-361. 10.3945/ajcn.2009.27630.CrossRefPubMed
45.
Tsugane S: Salt, salted food intake, and risk of gastric cancer: epidemiologic evidence. Cancer Sci. 2005, 96: 1-6. 10.1111/j.1349-7006.2005.00006.x.CrossRefPubMed
46.
Kono S, Hirohata T: Nutrition and stomach cancer. Cancer Causes Control. 1996, 7: 41-55. 10.1007/BF00115637.CrossRefPubMed
47.
World Cancer Research Fund, American Institute for Cancer Research: Food, Nutrition and the Prevention of Cancer: a Global Perspective. 1997, Washington: American Institute for Cancer Research
48.
Ward MH, Lopez-Carrillo L: Dietary factors and the risk of gastric cancer in Mexico City. Am J Epidemiol. 1999, 149: 925-932.CrossRefPubMed
49.
Tsugane S, Sasazuki S, Kobayashi M, Sasaki S: Salt and salted food intake and subsequent risk of gastric cancer among middle-aged Japanese men and women. Br J Cancer. 2004, 90: 128-134. 10.1038/sj.bjc.6601511.CrossRefPubMedPubMedCentral
50.
Kim HJ, Chang WK, Kim MK, Lee SS, Choi BY: Dietary factors and gastric cancer in Korea: a case-control study. Int J Cancer. 2002, 97: 531-535. 10.1002/ijc.10111.CrossRefPubMed
51.
Larsson SC, Orsini N, Wolk A: Processed meat consumption and stomach cancer risk: a meta-analysis. J Natl Cancer Inst. 2006, 98: 1078-1087. 10.1093/jnci/djj301.CrossRefPubMed
52.
Jakszyn P, Gonzalez CA: Nitrosamine and related food intakeand gastric and oesophageal cancer risk: a systematicreview of the epidemiological evidence. World J Gastroen-terol. 2006, 12: 4296-4303.CrossRef
53.
World Cancer Research Fund/American Institute for Cancer Research: Food, nutrition, physical activity, and the prevention of cancer: a global perspective. 2007, Washington, DC: American Institute for Cancer Research
54.
Mirvish SS: Role of N-nitroso compounds (NOC) andN-nitrosation in etiology of gastric, esophageal, naso-pharyngeal and bladder cancer and contribution to cancerof known exposures to NOC. Cancer Lett. 1995, 93: 17-48. 10.1016/0304-3835(95)03786-V.CrossRefPubMed
55.
Dich J, Jarvinen R, Knekt P, Penttila PL: Dietary intakes of nitrate, nitrite and NDMA in the Finnish Mobile Clinic Health Examination Survey. Food Addit Contam. 1996, 13: 541-552.CrossRefPubMed
56.
Knekt P, Jarvinen R, Dich J, Hakulinen T: Risk of colorectal and other gastro-intestinal cancers after exposure to nitrate, nitrite and N-nitroso compounds: a follow-up study. Int J Cancer. 1999, 80: 852-856. 10.1002/(SICI)1097-0215(19990315)80:6<852::AID-IJC9>3.0.CO;2-S.CrossRefPubMed
57.
Bingham SA, Pignatelli B, Pollock JR, Ellul A, Malaveille C, Gross G, Runswick S, Cummings JH, O'Neill IK: Does increased endogenous formation of N-nitroso compounds in the human colon explain the association between red meat and colon cancer?. Carcinogenesis. 1996, 17: 515-523. 10.1093/carcin/17.3.515.CrossRefPubMed
58.
Skog KI, Johansson MA, Jagerstad MI: Carcinogenic heterocyclic amines in model systems and cooked foods: a review on formation, occurrence and intake. Food Chem Toxicol. 1998, 36: 879-896. 10.1016/S0278-6915(98)00061-1.CrossRefPubMed
59.
Chen W, Weisburger JH, Fiala ES, Spratt TE, Carmella SG, Chen D, Hecht SS: Gastric carcinogenesis: 2-chloro-4-methylthiobutanoic acid, a novel mutagen in salted, pickled Sanma hiraki fish, or similarly treated methionine. Chem Res Toxicol. 1996, 9: 58-66. 10.1021/tx9500585.CrossRefPubMed
60.
Lauren P: The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand. 1965, 64: 31-49.PubMed
61.
Palli D, Bianchi S, Cipriani F, Duca P, Amorosi A, Avellini C, Russo A, Saragoni A, Todde P, Valdes E, Vindigni C, Blot WJ, Fraumeni JF, Buiattil Jr: Reproducibility of histologic classification of gastric cancer. Br J Cancer. 1991, 63: 765-768. 10.1038/bjc.1991.171.CrossRefPubMedPubMedCentral
62.
Correa P, Shiao YH: Phenotypic and genotypic events in gastric carcinogenesis. Cancer Res. 1994, 54: 1941S-1943S.PubMed
63.
Harrison LE, Zhang ZF, Karpeh MS, Sun M, Kurtz RC: The role of dietary factors in the intestinal and diffuse histologic subtypes of gastric adenocarcinoma: a case-control study in the U.S. Cancer. 1997, 80: 1021-1028. 10.1002/(SICI)1097-0142(19970915)80:6<1021::AID-CNCR3>3.0.CO;2-C.CrossRefPubMed
64.
Koh TJ, Wang TC: Tumors of the stomach. Sleisenger and Fordtran's gastrointestinal and liver disease: pathophysiology, diagnosis, and management. Edited by: Feldman M. 2001, Philadelphia, Saunders, 829-851.
65.
Larsson SC, Giovannucci E, Wolk A: Folate intake and stomach cancer incidence in a prospective cohort of Swedish women. Cancer Epidemiol Biomarkers Prev. 2006, 15: 1409-1412. 10.1158/1055-9965.EPI-05-0830.CrossRefPubMed
66.
Larsson SC, Bergkvist L, Wolk A: Processed meat consumption, dietary nitrosamines and stomach cancer risk in a cohort of Swedish women. Int J Cancer. 2006, 119: 915-919. 10.1002/ijc.21925.CrossRefPubMed
67.
Hilakivi-Clarke L, Olivo SE, Shajahan A, Khan G, Zhu Y, Zwart A, Cho E, Clarke R: Mechanisms mediating the effects of prepubertal (n-3) polyunsaturated fatty acid diet on breast cancer risk in rats. J Nutr. 2005, 135: 2946S-2952S.PubMed
68.
Ford JH: Saturated fatty acid metabolism is key link between cell division, cancer, and senescence in cellular and whole organism aging. Age (Dordr). 2010, 32: 231-237. 10.1007/s11357-009-9128-x.CrossRef
69.
James MJ, Proudman SM, Cleland LG: Dietary n-3 fats as adjunctive therapy in a prototypic inflammatory disease: issues and obstacles for use in rheumatoid arthritis. Prostaglandins Leukot Essent Fatty Acids. 2003, 68: 399-405. 10.1016/S0952-3278(03)00064-4.CrossRefPubMed
70.
Cerchietti LC, Navigante AH, Castro MA: Effects of eicosapentaenoic and docosahexaenoic n-3 fatty acids from fish oil and preferential Cox-2 inhibition on systemic syndromes in patients with advanced lung cancer. Nutr Cancer. 2007, 59: 14-20.CrossRefPubMed
71.
Stoll BA: N-3 fatty acids and lipid peroxidation in breast cancer inhibition. Br J Nutr. 2002, 87: 193-198. 10.1079/BJN2001512.CrossRefPubMed
72.
Roynette CE, Calder PC, Dupertuis YM, Pichard C: n-3 polyunsaturated fatty acids and colon cancer prevention. Clin Nutr. 2004, 23: 139-151. 10.1016/j.clnu.2003.07.005.CrossRefPubMed
73.
Chapkin RS, Davidson LA, Ly L, Weeks BR, Lupton JR, McMurray DN: Immunomodulatory effects of (n-3) fatty acids: putative link to inflammation and colon cancer. J Nutr. 2007, 137 (Suppl 1): 200S-204S.PubMed
74.
Dai Q, Shu XO, Jin F, Gao YT, Ruan ZX, Zheng W: Consumption of animal foods, cooking methods, and risk of breast cancer. Cancer Epidemiol Biomarkers Prev. 2002, 11: 801-818.PubMed
75.
van Vliet T, Katan MB: Lower ratio of n-3 to n-6 fatty acids in cultured than in wild fish. Am J Clin Nutr. 1990, 51: 1-2.PubMed
76.
Gago-Dominguez M, Yuan JM, Sun CL, Lee HP, Yu MC: Opposing effects of dietary n-3 and n-6 fatty acids on mammary carcinogenesis: The Singapore Chinese Health Study. Br J Cancer. 2003, 89: 1686-1692. 10.1038/sj.bjc.6601340.CrossRefPubMedPubMedCentral
77.
Hall MN, Campos H, Li H, Sesso HD, Stampfer MJ, Willett WC, Ma J: Blood levels of long-chain polyunsaturated fatty acids, aspirin, and the risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2007, New York, Oxford: Oxford University Press, 16: 314-321. 10.1158/1055-9965.EPI-06-0346.
78.
Willett W: Food-frequency methods. Nutritional epidemiology. Edited by: Willett W. 1998, New York, Oxford: Oxford University Press, 74-100. full_text. 2CrossRef
79.
Mayer-Davis EJ, Vitolins MZ, Carmichael SL, Hemphill S, Tsaroucha G, Rushing J, Levin S: Validity and reproducibility of a food frequency interview in a Multi-Cultural Epidemiology Study. Ann Epidemiol. 1999, 9: 314-324. 10.1016/S1047-2797(98)00070-2.CrossRefPubMed
Metadata
Title
Fish consumption and the risk of gastric cancer: systematic review and meta-analysis
Authors
Shengjun Wu
Jie Liang
Lei Zhang
Xia Zhu
Xufeng Liu
Danmin Miao
Publication date
01-12-2011
Publisher
BioMed Central
Published in
BMC Cancer / Issue 1/2011
Electronic ISSN: 1471-2407
DOI
https://doi.org/10.1186/1471-2407-11-26

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