Skip to main content
Top
Published in: BMC Pregnancy and Childbirth 1/2012

Open Access 01-12-2012 | Research article

Striving for scientific stringency: a re-analysis of a randomised controlled trial considering first-time mothers’ obstetric outcomes in relation to birth position

Authors: Li Thies-Lagergren, Linda J Kvist, Kyllike Christensson, Ingegerd Hildingsson

Published in: BMC Pregnancy and Childbirth | Issue 1/2012

Login to get access

Abstract

Background

The aim of this study was to compare maternal labour and birth outcomes between women who gave birth on a birth seat or in any other position for vaginal birth and further, to study the relationship between synthetic oxytocin augmentation and maternal blood loss, in a stratified sample.

Methods

A re-analysis of a randomized controlled trial in Sweden. An on-treatment analysis was used to study obstetrical outcomes for nulliparous women who gave birth on a birth seat (birth seat group) compared to birth in any other position for vaginal birth (control group). Data were collected between November 2006 and July 2009. The outcome measurements included perineal outcome, post partum blood loss, epidural analgesia, synthetic oxytocin augmentation and duration of labour.

Results

The major findings of this paper were that women giving birth on the birth seat had shorter duration of labour and were significantly less likely to receive synthetic oxytocin for augmentation in the second stage of labour. Significantly more women had an increased blood loss when giving birth on the birth seat, but had no difference in perineal outcomes. Blood loss was increased regardless of birth position if women had been exposed to synthetic oxytocin augmentation during the first stage of labour.

Conclusions

The results of this analysis imply that women with a straightforward birth process may well benefit from giving birth on a birth seat without risk for any adverse obstetrical outcomes. However it is important to bear in mind that, women who received synthetic oxytocin during the first stage of labour may have an increased risk for greater blood loss when giving birth on a birth seat. Finally it is of vital importance to scrutinize the influence of synthetic oxytocin administered during the first stage of labour on blood loss postpartum, since excessive blood loss is a well-documented cause of maternal mortality worldwide and may cause severe maternal morbidity in high-income countries.

Trial registration

Unique Protocol ID: NCT01182038 (http://​register.​clinicaltrials.​gov)
Literature
1.
go back to reference O'dowd MJ, Philipp EE: The history of obstetrics and gynaecology. 1994, England: Parthenon Pub Group O'dowd MJ, Philipp EE: The history of obstetrics and gynaecology. 1994, England: Parthenon Pub Group
2.
go back to reference Lewis G: Saving Mothers’ Lives: The Continuing Benefits for Maternal Health From the United Kingdom (UK) Confidential Enquires Into Maternal Deaths. Semin Perinatol. 2012, 36 (1): 19-26. 10.1053/j.semperi.2011.09.005.CrossRefPubMed Lewis G: Saving Mothers’ Lives: The Continuing Benefits for Maternal Health From the United Kingdom (UK) Confidential Enquires Into Maternal Deaths. Semin Perinatol. 2012, 36 (1): 19-26. 10.1053/j.semperi.2011.09.005.CrossRefPubMed
3.
go back to reference Van Teijlingen E: A Critical Analysis of the Medical Model as used in the Study of Pregnancy and Childbirth. Sociological Research Online. 2005, 10 (2): Van Teijlingen E: A Critical Analysis of the Medical Model as used in the Study of Pregnancy and Childbirth. Sociological Research Online. 2005, 10 (2):
4.
go back to reference Jordan RG, Murphy PA: Risk assessment and risk distortion: finding the balance. J Midwifery Womens Health. 2009, 54 (3): 191-200. 10.1016/j.jmwh.2009.02.001.CrossRefPubMed Jordan RG, Murphy PA: Risk assessment and risk distortion: finding the balance. J Midwifery Womens Health. 2009, 54 (3): 191-200. 10.1016/j.jmwh.2009.02.001.CrossRefPubMed
5.
go back to reference Tracy SK, Sullivan E, Wang YA, Black D, Tracy M: Birth outcomes associated with interventions in labour amongst low risk women: A population-based study. Women Birth. 2007, 20 (2): 41-48. 10.1016/j.wombi.2007.03.005.CrossRefPubMed Tracy SK, Sullivan E, Wang YA, Black D, Tracy M: Birth outcomes associated with interventions in labour amongst low risk women: A population-based study. Women Birth. 2007, 20 (2): 41-48. 10.1016/j.wombi.2007.03.005.CrossRefPubMed
6.
go back to reference Kukla R, Wayne K: The Stanford Encyclopedia of Philosophy. Pregnancy, Birth, and Medicine. 2011 Kukla R, Wayne K: The Stanford Encyclopedia of Philosophy. Pregnancy, Birth, and Medicine. 2011
7.
go back to reference Lavender T, Mlay R: The WHO Reproductive Health Library. Position in the second stage of labour for women without epidural anaesthesia: RHL commentary. 2006 Lavender T, Mlay R: The WHO Reproductive Health Library. Position in the second stage of labour for women without epidural anaesthesia: RHL commentary. 2006
8.
go back to reference de Jonge A, Lagro-Janssen AL: Increased blood loss in upright positions originates from perineal damage. BJOG. 2007, 114 (3): 349-355. 10.1111/j.1471-0528.2006.01210.x.CrossRefPubMed de Jonge A, Lagro-Janssen AL: Increased blood loss in upright positions originates from perineal damage. BJOG. 2007, 114 (3): 349-355. 10.1111/j.1471-0528.2006.01210.x.CrossRefPubMed
9.
go back to reference Thies-Lagergren L, Kvist LJ, Christensson K, Hildingsson I: No reduction in instrumental vaginal births and no increased risk for adverse perineal outcome in nulliparous women giving birth on a birth seat: results of a Swedish randomized controlled trial. BMC Pregnancy Childbirth. 2011, 11: 22-10.1186/1471-2393-11-22.CrossRefPubMedPubMedCentral Thies-Lagergren L, Kvist LJ, Christensson K, Hildingsson I: No reduction in instrumental vaginal births and no increased risk for adverse perineal outcome in nulliparous women giving birth on a birth seat: results of a Swedish randomized controlled trial. BMC Pregnancy Childbirth. 2011, 11: 22-10.1186/1471-2393-11-22.CrossRefPubMedPubMedCentral
10.
go back to reference Waldenström U, Gottval K: Randomized trial of birthing stool or conventional semi-recumbent position for second-stage labor. Birth. 1991, 18 (1): 5-10. 10.1111/j.1523-536X.1991.tb00045.x.CrossRefPubMed Waldenström U, Gottval K: Randomized trial of birthing stool or conventional semi-recumbent position for second-stage labor. Birth. 1991, 18 (1): 5-10. 10.1111/j.1523-536X.1991.tb00045.x.CrossRefPubMed
11.
go back to reference Thies-Lagergren L, Kvist LJ, Sandin-Bojö AK, Christensson K, Hildingsson I: Augmentation of labour and fetal outcomes in relation to birth positions: a secondary analysis of an RCT evaluating birth seat births. Midwifery. 2012, In Press Thies-Lagergren L, Kvist LJ, Sandin-Bojö AK, Christensson K, Hildingsson I: Augmentation of labour and fetal outcomes in relation to birth positions: a secondary analysis of an RCT evaluating birth seat births. Midwifery. 2012, In Press
12.
go back to reference Foureur M: Randomised Controlled Trials in Nursing and Midwifery: An Interview with Maralyn Foureur. Nurs Prax NZ. 2002, 18: 4-16. Foureur M: Randomised Controlled Trials in Nursing and Midwifery: An Interview with Maralyn Foureur. Nurs Prax NZ. 2002, 18: 4-16.
13.
go back to reference Jadad AR, Enkin MW: Bias in Randomized Controlled Trials, in Randomized Controlled Trials: Questions, Answers, and Musings. 2008, Oxford, UK: Blackwell Publishing Ltd, 2 Jadad AR, Enkin MW: Bias in Randomized Controlled Trials, in Randomized Controlled Trials: Questions, Answers, and Musings. 2008, Oxford, UK: Blackwell Publishing Ltd, 2
14.
go back to reference Clausen JA: Promoting Normal Birth: Research, Reflections and Guidelines. RCTs and everyday practices… a troubled relationship. 2011, UK: Fresh Heart Books for Better Birth, 127-138. Clausen JA: Promoting Normal Birth: Research, Reflections and Guidelines. RCTs and everyday practices… a troubled relationship. 2011, UK: Fresh Heart Books for Better Birth, 127-138.
15.
go back to reference Johnson KC: Childbirth and authoritative knowledge: cross-cultural perspectives. Randomized Controlled Trials as Authoritative Knowledge. 1997, 350- Johnson KC: Childbirth and authoritative knowledge: cross-cultural perspectives. Randomized Controlled Trials as Authoritative Knowledge. 1997, 350-
16.
go back to reference Hernan MA, Hernandez-Diaz S: Beyond the intention-to-treat in comparative effectiveness research. Clin Trials. 2012, 9 (1): 48-55. 10.1177/1740774511420743.CrossRefPubMed Hernan MA, Hernandez-Diaz S: Beyond the intention-to-treat in comparative effectiveness research. Clin Trials. 2012, 9 (1): 48-55. 10.1177/1740774511420743.CrossRefPubMed
18.
go back to reference Hewitt CE, Torgerson DJ, Miles JN: Is there another way to take account of noncompliance in randomized controlled trials?. CMAJ. 2006, 175 (4): 347-10.1503/cmaj.051625.CrossRefPubMedPubMedCentral Hewitt CE, Torgerson DJ, Miles JN: Is there another way to take account of noncompliance in randomized controlled trials?. CMAJ. 2006, 175 (4): 347-10.1503/cmaj.051625.CrossRefPubMedPubMedCentral
19.
go back to reference Gardosi J, Sylvester S, B-Lynch C: Alternative positions in the second stage of labour: a randomised controlled trial. Br J Obstet Gynaecol. 1989, 96: 1290-1296. 10.1111/j.1471-0528.1989.tb03226.x.CrossRefPubMed Gardosi J, Sylvester S, B-Lynch C: Alternative positions in the second stage of labour: a randomised controlled trial. Br J Obstet Gynaecol. 1989, 96: 1290-1296. 10.1111/j.1471-0528.1989.tb03226.x.CrossRefPubMed
20.
go back to reference de Jong P, Johanson R, Baxen P, Adrians V, vander Westhuisen S, Jones P: Randomised trial comparing the upright and supine positions for the second stage of labour. Br J Obstet Gynaecol. 1997, 104 (5): 567-571. 10.1111/j.1471-0528.1997.tb11534.x.CrossRefPubMed de Jong P, Johanson R, Baxen P, Adrians V, vander Westhuisen S, Jones P: Randomised trial comparing the upright and supine positions for the second stage of labour. Br J Obstet Gynaecol. 1997, 104 (5): 567-571. 10.1111/j.1471-0528.1997.tb11534.x.CrossRefPubMed
21.
go back to reference Bodner-Adler B, Bodner K, Kimberger O, Lozanov P, Husslein P, Mayerhofer K: Women’s position during labour: influence on maternal and neonatal outcome. Wien Klin Wochenschr. 2003, 115 (19): 720-723. 10.1007/BF03040889.CrossRefPubMed Bodner-Adler B, Bodner K, Kimberger O, Lozanov P, Husslein P, Mayerhofer K: Women’s position during labour: influence on maternal and neonatal outcome. Wien Klin Wochenschr. 2003, 115 (19): 720-723. 10.1007/BF03040889.CrossRefPubMed
22.
go back to reference Gupta J, Justus HG, Shehmar M: Cochrane Database of Systematic Reviews. Position in the second stage of labour for women without epidural anaesthesia. 2012CrossRef Gupta J, Justus HG, Shehmar M: Cochrane Database of Systematic Reviews. Position in the second stage of labour for women without epidural anaesthesia. 2012CrossRef
23.
go back to reference de Jonge A, Teunissen DAM, Van Diem MT, Scheepers PLH, Lagro-Jansen ALM: Women’s positions during the second stage of labour: views of primary care midwives. J Adv Nurs. 2008, 63 (4): 347-356. 10.1111/j.1365-2648.2008.04703.x.CrossRefPubMed de Jonge A, Teunissen DAM, Van Diem MT, Scheepers PLH, Lagro-Jansen ALM: Women’s positions during the second stage of labour: views of primary care midwives. J Adv Nurs. 2008, 63 (4): 347-356. 10.1111/j.1365-2648.2008.04703.x.CrossRefPubMed
24.
go back to reference Enkin M, Keirse M, Neilson J, Crowther C, Duley L, Hodnett E: The Second Stage ofLabor. A Guide to Effective Care in Pregnancy and Childbirth. 2000, Oxford, UK: Oxford University PressCrossRef Enkin M, Keirse M, Neilson J, Crowther C, Duley L, Hodnett E: The Second Stage ofLabor. A Guide to Effective Care in Pregnancy and Childbirth. 2000, Oxford, UK: Oxford University PressCrossRef
25.
go back to reference Prata N, Hamza S, Bell S, Karasek D, Vahidnia F, Holston M: Inability to predict postpartum haemorrhage: insights from Egyptian intervention data. BMC Pregnancy Childbirth. 2011, 11: 97-10.1186/1471-2393-11-97.CrossRefPubMedPubMedCentral Prata N, Hamza S, Bell S, Karasek D, Vahidnia F, Holston M: Inability to predict postpartum haemorrhage: insights from Egyptian intervention data. BMC Pregnancy Childbirth. 2011, 11: 97-10.1186/1471-2393-11-97.CrossRefPubMedPubMedCentral
26.
go back to reference Belghiti J, Kayem G, Dupont C, Rudigoz RC, Bouvier-Colle MH, Deneux-Tharaux C: Oxytocin during labour and risk of severe postpartum haemorrhage: a population-based, cohort-nested case–control study. BMJ Open. 2011, 1 (2): 1-9.CrossRef Belghiti J, Kayem G, Dupont C, Rudigoz RC, Bouvier-Colle MH, Deneux-Tharaux C: Oxytocin during labour and risk of severe postpartum haemorrhage: a population-based, cohort-nested case–control study. BMJ Open. 2011, 1 (2): 1-9.CrossRef
27.
go back to reference Scamell M, Alaszewski A: Fateful moments and the categorisation of risk: Midwifery practice and the ever-narrowing window of normality during childbirth. Health, Risk & Society. 2012, 14 (2): 207-221. 10.1080/13698575.2012.661041.CrossRef Scamell M, Alaszewski A: Fateful moments and the categorisation of risk: Midwifery practice and the ever-narrowing window of normality during childbirth. Health, Risk & Society. 2012, 14 (2): 207-221. 10.1080/13698575.2012.661041.CrossRef
28.
go back to reference Wiklund I, Wallin J, Vikström M, Ransjö-Arvidson AB: Swedish midwives’ rating of risks during labour progress and their attitudes toward performing intrapartum interventions: a web-based survey. Midwifery. 2011, 28 (4): 516-520.CrossRef Wiklund I, Wallin J, Vikström M, Ransjö-Arvidson AB: Swedish midwives’ rating of risks during labour progress and their attitudes toward performing intrapartum interventions: a web-based survey. Midwifery. 2011, 28 (4): 516-520.CrossRef
29.
go back to reference Hundley V, Cheyne H: The trials and tribulations of intrapartum studies. Midwifery. 2004, 20 (1): 27-36. 10.1016/S0266-6138(03)00050-0.CrossRefPubMed Hundley V, Cheyne H: The trials and tribulations of intrapartum studies. Midwifery. 2004, 20 (1): 27-36. 10.1016/S0266-6138(03)00050-0.CrossRefPubMed
30.
go back to reference Herigon JC, Newland JG: The Role of Intention-to-Treat Analyses in Randomized Trials. Infect Control Hosp Epidemiol. 2012, 33 (2): 207-208. 10.1086/663963.CrossRefPubMed Herigon JC, Newland JG: The Role of Intention-to-Treat Analyses in Randomized Trials. Infect Control Hosp Epidemiol. 2012, 33 (2): 207-208. 10.1086/663963.CrossRefPubMed
Metadata
Title
Striving for scientific stringency: a re-analysis of a randomised controlled trial considering first-time mothers’ obstetric outcomes in relation to birth position
Authors
Li Thies-Lagergren
Linda J Kvist
Kyllike Christensson
Ingegerd Hildingsson
Publication date
01-12-2012
Publisher
BioMed Central
Published in
BMC Pregnancy and Childbirth / Issue 1/2012
Electronic ISSN: 1471-2393
DOI
https://doi.org/10.1186/1471-2393-12-135

Other articles of this Issue 1/2012

BMC Pregnancy and Childbirth 1/2012 Go to the issue