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Published in: BMC Primary Care 1/2011

Open Access 01-12-2011 | Research article

Management of asthma in pregnant women by general practitioners: A cross sectional survey

Authors: Angelina S Lim, Kay Stewart, Michael J Abramson, Johnson George

Published in: BMC Primary Care | Issue 1/2011

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Abstract

Background

Poorly controlled asthma can lead to maternal and fetal complications. Despite the known risks of poorly controlled asthma during pregnancy and the need for stepping up therapy when appropriate, there are concerns that management is suboptimal in primary care.
Our objective was to investigate the management of asthma during pregnancy by general practitioners providing shared maternity care.

Methods

A pre-piloted, anonymous mail survey was sent to all general practitioners (n = 842) involved in shared maternity care at six maternity hospitals in Victoria, Australia. Respondents were asked about their perceived safety of individual asthma medications during pregnancy. Approach to asthma management during pregnancy was further explored using scenarios of pregnant women with stable and deteriorating asthma and poor medication adherence.

Results

Inhaled corticosteroids (ICS) were perceived to be the safest and were the preferred preventive medication in first trimester (74.1%), whilst leukotriene receptor antagonists were the least preferred (2.9%). A quarter (25.8%) of respondents would stop or decrease patients' ICS doses during pregnancy, even when their asthma was well controlled by current therapy. In addition, 12.1% of respondents were not sure how to manage deteriorating asthma during pregnancy and opted to refer to another health professional. Almost half the respondents (48.9%) reported encountering medication nonadherence during pregnancy.

Conclusion

A lack of confidence and/or knowledge among general practitioners in managing deteriorating asthma in pregnancy was observed despite a good understanding of the safety of asthma medications during pregnancy, compliance with evidence-based guidelines in the selection of preventive medications, and self reported good asthma knowledge.
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Literature
1.
go back to reference Murphy VE, Namazy JA, Powell H, Schatz M, Chambers C, Attia J, Gibson PG: A meta-analysis of adverse perinatal outcomes in women with asthma. BJOG. 2011, 118: 1314-1323. 10.1111/j.1471-0528.2011.03055.x.CrossRefPubMed Murphy VE, Namazy JA, Powell H, Schatz M, Chambers C, Attia J, Gibson PG: A meta-analysis of adverse perinatal outcomes in women with asthma. BJOG. 2011, 118: 1314-1323. 10.1111/j.1471-0528.2011.03055.x.CrossRefPubMed
2.
go back to reference Sugai K, Ito M, Tateishi I, Funabiki T, Nishikawa M: Neonatal periventricular leukomalacia due to severe, poorly controlled asthma in the mother. Allergol Int. 2006, 55: 207-212. 10.2332/allergolint.55.207.CrossRefPubMed Sugai K, Ito M, Tateishi I, Funabiki T, Nishikawa M: Neonatal periventricular leukomalacia due to severe, poorly controlled asthma in the mother. Allergol Int. 2006, 55: 207-212. 10.2332/allergolint.55.207.CrossRefPubMed
3.
go back to reference Whincup P, Cook D, Papacosta O, Walker M: Birth weight and blood pressure: cross sectional and longitudinal relations in childhood. BMJ. 1995, 311: 773-776. 10.1136/bmj.311.7008.773.CrossRefPubMedPubMedCentral Whincup P, Cook D, Papacosta O, Walker M: Birth weight and blood pressure: cross sectional and longitudinal relations in childhood. BMJ. 1995, 311: 773-776. 10.1136/bmj.311.7008.773.CrossRefPubMedPubMedCentral
4.
go back to reference Benediktsson R, Lindsay RS, Noble J, Seckl JR, Edwards CRW: Glucocorticoid exposure in utero: new model for adult hypertension. The Lancet. 1993, 341: 339-341. 10.1016/0140-6736(93)90138-7.CrossRef Benediktsson R, Lindsay RS, Noble J, Seckl JR, Edwards CRW: Glucocorticoid exposure in utero: new model for adult hypertension. The Lancet. 1993, 341: 339-341. 10.1016/0140-6736(93)90138-7.CrossRef
5.
go back to reference Levine RS, Hennekens CH, Jesse MJ: Blood pressure in prospective population based cohort of newborn and infant twins. BMJ. 1994, 308: 298-302. 10.1136/bmj.308.6924.298.CrossRefPubMedPubMedCentral Levine RS, Hennekens CH, Jesse MJ: Blood pressure in prospective population based cohort of newborn and infant twins. BMJ. 1994, 308: 298-302. 10.1136/bmj.308.6924.298.CrossRefPubMedPubMedCentral
6.
go back to reference Barker DJP: Fetal nutrition and cardiovascular disease in later life. Br Med Bull. 1997, 53: 96-108.CrossRefPubMed Barker DJP: Fetal nutrition and cardiovascular disease in later life. Br Med Bull. 1997, 53: 96-108.CrossRefPubMed
7.
go back to reference Edwards CRW, Benediktsson R, Lindsay RS, Seckl JR: Dysfunction of placental glucocorticoid barrier: link between fetal environment and adult hypertension?. The Lancet. 1993, 341: 355-357. 10.1016/0140-6736(93)90148-A.CrossRef Edwards CRW, Benediktsson R, Lindsay RS, Seckl JR: Dysfunction of placental glucocorticoid barrier: link between fetal environment and adult hypertension?. The Lancet. 1993, 341: 355-357. 10.1016/0140-6736(93)90148-A.CrossRef
8.
go back to reference Lao TT, Huengsburg M: Labour and delivery in mothers with asthma. Eur J Obstet Gynecol Reprod Biol. 1990, 35: 183-190. 10.1016/0028-2243(90)90160-3.CrossRefPubMed Lao TT, Huengsburg M: Labour and delivery in mothers with asthma. Eur J Obstet Gynecol Reprod Biol. 1990, 35: 183-190. 10.1016/0028-2243(90)90160-3.CrossRefPubMed
9.
11.
go back to reference Murphy VE, Clifton VL, Gibson PG: Asthma exacerbations during pregnancy: incidence and association with adverse pregnancy outcomes. Thorax. 2006, 61: 169-176. 10.1136/thx.2005.049718.CrossRefPubMedPubMedCentral Murphy VE, Clifton VL, Gibson PG: Asthma exacerbations during pregnancy: incidence and association with adverse pregnancy outcomes. Thorax. 2006, 61: 169-176. 10.1136/thx.2005.049718.CrossRefPubMedPubMedCentral
12.
go back to reference Chambers K: Asthma education and outcomes for women of childbearing age. Case Manager. 2003, 14: 58-61.CrossRefPubMed Chambers K: Asthma education and outcomes for women of childbearing age. Case Manager. 2003, 14: 58-61.CrossRefPubMed
13.
go back to reference Olesen C, Thrane N, Nielsen GL, Sørensen HT, Olsen J: A Population-Based Prescription Study of Asthma Drugs during Pregnancy: Changing the Intensity of Asthma Therapy and Perinatal Outcomes. Respiration. 2001, 68: 256-261. 10.1159/000050507.CrossRefPubMed Olesen C, Thrane N, Nielsen GL, Sørensen HT, Olsen J: A Population-Based Prescription Study of Asthma Drugs during Pregnancy: Changing the Intensity of Asthma Therapy and Perinatal Outcomes. Respiration. 2001, 68: 256-261. 10.1159/000050507.CrossRefPubMed
14.
go back to reference British Thoracic Society. Asthma in pregnancy. British guidelines on the management of asthma. 2009, Edinburgh, Scottish Intercollegiate Guideline Networks, 71-72. British Thoracic Society. Asthma in pregnancy. British guidelines on the management of asthma. 2009, Edinburgh, Scottish Intercollegiate Guideline Networks, 71-72.
15.
go back to reference Global Initiative for Asthma. Special considerations- pregnancy. Global strategy for asthma management and prevention. 2008, Cape town, Medical Communication Resources Inc, 70-71. update Global Initiative for Asthma. Special considerations- pregnancy. Global strategy for asthma management and prevention. 2008, Cape town, Medical Communication Resources Inc, 70-71. update
16.
go back to reference National Asthma Council of Australia. Pregnancy and asthma. Asthma Management Handbook. 2006, Melbourne, National Asthma Council Ltd, 101-103. National Asthma Council of Australia. Pregnancy and asthma. Asthma Management Handbook. 2006, Melbourne, National Asthma Council Ltd, 101-103.
17.
go back to reference National Heart, Lung and Blood Institute: NAEPP expert panel report. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. J Allergy Clin Immunol. 2005, 115: 34-46. 10.1016/j.jaci.2004.10.023.CrossRef National Heart, Lung and Blood Institute: NAEPP expert panel report. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. J Allergy Clin Immunol. 2005, 115: 34-46. 10.1016/j.jaci.2004.10.023.CrossRef
18.
go back to reference American College of Obstetricians and Gynecologists and the American College of Allergy, Asthma and Immunology. Position statement: the use of newer asthma and allergy medications during pregnancy. Ann Allergy Asthma Immunol. 2000, 84: 475-80. 10.1016/S1081-1206(10)62505-7. American College of Obstetricians and Gynecologists and the American College of Allergy, Asthma and Immunology. Position statement: the use of newer asthma and allergy medications during pregnancy. Ann Allergy Asthma Immunol. 2000, 84: 475-80. 10.1016/S1081-1206(10)62505-7.
19.
go back to reference Lim A, Stewart K, König K, George J: Systematic Review of the Safety of Regular Preventive Asthma Medications During Pregnancy. Ann Pharmacother. 2011, 45: 931-945. 10.1345/aph.1P764.CrossRefPubMed Lim A, Stewart K, König K, George J: Systematic Review of the Safety of Regular Preventive Asthma Medications During Pregnancy. Ann Pharmacother. 2011, 45: 931-945. 10.1345/aph.1P764.CrossRefPubMed
20.
go back to reference Morgan MA, Cragan JD, Goldenberg RL, Rasmussen SA, Schulkin J: Management of prescription and nonprescription drug use during pregnancy. J Matern Fetal Neonatal Med. 2010, 23: 813-819. 10.3109/14767050903387045.CrossRefPubMed Morgan MA, Cragan JD, Goldenberg RL, Rasmussen SA, Schulkin J: Management of prescription and nonprescription drug use during pregnancy. J Matern Fetal Neonatal Med. 2010, 23: 813-819. 10.3109/14767050903387045.CrossRefPubMed
21.
go back to reference Piette J, Heisler M, Wagner T: Cost-related medication underuse: do patients with chronic illness tell their doctors?. Arch Intern Med. 2004, 164: 1749-1755. 10.1001/archinte.164.16.1749.CrossRefPubMed Piette J, Heisler M, Wagner T: Cost-related medication underuse: do patients with chronic illness tell their doctors?. Arch Intern Med. 2004, 164: 1749-1755. 10.1001/archinte.164.16.1749.CrossRefPubMed
22.
go back to reference National Asthma Council of Australia. Ongoing Care. Asthma Management Handbook. 2006, Melbourne, National Asthma Council Ltd, 78- National Asthma Council of Australia. Ongoing Care. Asthma Management Handbook. 2006, Melbourne, National Asthma Council Ltd, 78-
23.
go back to reference Morgan MA, Cragan JD, Goldenberg RL, Rasmussen SA, Schulkin J: Obstetrician-gynaecologist knowledge of and access to information about the risks of medication use during pregnancy. J Matern Fetal Neonatal Med. 2010, 23: 1143-1150. 10.3109/14767051003653252.CrossRefPubMed Morgan MA, Cragan JD, Goldenberg RL, Rasmussen SA, Schulkin J: Obstetrician-gynaecologist knowledge of and access to information about the risks of medication use during pregnancy. J Matern Fetal Neonatal Med. 2010, 23: 1143-1150. 10.3109/14767051003653252.CrossRefPubMed
24.
go back to reference Britt H, Miller G, Charles J, Valenti L, Fahridin S, Pan Y, Harrison C, Bayram C, O'Halloran J, Henderson J: General Practice activity in Australia 2009-10. General practice series no.27. Cat no. GEP 27. 2010, Canberra: AIHW Britt H, Miller G, Charles J, Valenti L, Fahridin S, Pan Y, Harrison C, Bayram C, O'Halloran J, Henderson J: General Practice activity in Australia 2009-10. General practice series no.27. Cat no. GEP 27. 2010, Canberra: AIHW
25.
go back to reference Pilotto LS, Smith BJ, Heard AR, McElroy HJ, Weekley J, Bennett P: Trial of nurse-run asthma clinics based in general practice versus usual medical care. Respirology. 2004, 9: 356-362. 10.1111/j.1440-1843.2004.00589.x.CrossRefPubMed Pilotto LS, Smith BJ, Heard AR, McElroy HJ, Weekley J, Bennett P: Trial of nurse-run asthma clinics based in general practice versus usual medical care. Respirology. 2004, 9: 356-362. 10.1111/j.1440-1843.2004.00589.x.CrossRefPubMed
26.
go back to reference Barclay S, Todd C, Finlay I, Grande G, Wyatt P: Not another questionnaire! Maximizing the response rate, predicting non-response and assessing non-response bias in postal questionnaire studies of GPs. Fam Pract. 2002, 19: 105-111. 10.1093/fampra/19.1.105.CrossRefPubMed Barclay S, Todd C, Finlay I, Grande G, Wyatt P: Not another questionnaire! Maximizing the response rate, predicting non-response and assessing non-response bias in postal questionnaire studies of GPs. Fam Pract. 2002, 19: 105-111. 10.1093/fampra/19.1.105.CrossRefPubMed
Metadata
Title
Management of asthma in pregnant women by general practitioners: A cross sectional survey
Authors
Angelina S Lim
Kay Stewart
Michael J Abramson
Johnson George
Publication date
01-12-2011
Publisher
BioMed Central
Published in
BMC Primary Care / Issue 1/2011
Electronic ISSN: 2731-4553
DOI
https://doi.org/10.1186/1471-2296-12-121

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