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BMC Medical Research Methodology
Published in: BMC Medical Research Methodology 1/2013

Open Access 01-12-2013 | Research article

A multi-state model to estimate incidence of heroin use

Authors: Albert Sánchez-Niubò, Odd O Aalen, Antònia Domingo-Salvany, Ellen J Amundsen, Josep Fortiana, Kjetil Røysland

Published in: BMC Medical Research Methodology | Issue 1/2013

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Abstract

Background

Existing incidence estimates of heroin use are usually based on one information source. This study aims to incorporate more sources to estimate heroin use incidence trends in Spain between 1971 and 2005.

Methods

A multi-state model was constructed, whereby the initial state “heroin consumer” is followed by transition to either “admitted to first treatment” or to “left heroin use” (i.e. permanent cessation or death). Heroin use incidence and probabilities of entering first treatment ever were estimated following a back-calculation approach.

Results

The highest heroin use incidence rates in Spain, around 1.5 per 1,000 inhabitants aged 10–44, occurred between 1985 and 1990; subdividing by route of administration reveals higher incidences of injection between 1980 and 1985 (a mean of 0.62 per 1.000) and a peak for non-injectors in 1990 (0.867 per 1,000).

Conclusions

A simple conceptual model for heroin users’ trajectories related to treatment admission, provided a broader view of the historical trend of heroin use incidence in Spain.
Appendix
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Metadata
Title
A multi-state model to estimate incidence of heroin use
Authors
Albert Sánchez-Niubò
Odd O Aalen
Antònia Domingo-Salvany
Ellen J Amundsen
Josep Fortiana
Kjetil Røysland
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Medical Research Methodology / Issue 1/2013
Electronic ISSN: 1471-2288
DOI
https://doi.org/10.1186/1471-2288-13-4

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