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Published in: The Journal of Headache and Pain 1/2015

Open Access 01-12-2015 | Invited speaker presentation

Proteomic research of proteins involved in pain expression in an animal model of chronic pain

Authors: Elisa Bellei, Stefania Bergamini, Emanuela Monari, Aurora Cuoghi, Michele Zoli, Aldo Tomasi, Maria Michela Cainazzo, Simona Guerzoni, Luigi Alberto Pini

Published in: The Journal of Headache and Pain | Special Issue 1/2015

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Excerpt

Pain is defined as an unpleasant sensory and emotional experience, associated with a real or potential tissue damage. Chronic pain (CP) can arise from tissue injuries or inflammation (inflammatory pain), or from lesions of the peripheral or central nervous system (neuropathic pain). The purpose of this study was to search proteins potentially involved in the expression or mediation of pain utilizing proteomic techniques, in an animal model of CP obtained by the ligation of the sciatic nerve. …
Literature
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go back to reference Seltzer Z, Dubner R, Shir Y: A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain. 1990, 43: 205-218. 10.1016/0304-3959(90)91074-S.CrossRefPubMed Seltzer Z, Dubner R, Shir Y: A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain. 1990, 43: 205-218. 10.1016/0304-3959(90)91074-S.CrossRefPubMed
2.
go back to reference Bellei E, Monari E, Cuoghi A, Bergamini S, Guerzoni S, Ciccarese M, Ozben T, Tomasi A, Pini LA: Discovery by a proteomic approach of possible early biomarkers of drug-induced nephrotoxicity in medication-overuse headache. J Headache Pain. 2013, 14: 6-10.1186/1129-2377-14-6.PubMedCentralCrossRefPubMed Bellei E, Monari E, Cuoghi A, Bergamini S, Guerzoni S, Ciccarese M, Ozben T, Tomasi A, Pini LA: Discovery by a proteomic approach of possible early biomarkers of drug-induced nephrotoxicity in medication-overuse headache. J Headache Pain. 2013, 14: 6-10.1186/1129-2377-14-6.PubMedCentralCrossRefPubMed
Metadata
Title
Proteomic research of proteins involved in pain expression in an animal model of chronic pain
Authors
Elisa Bellei
Stefania Bergamini
Emanuela Monari
Aurora Cuoghi
Michele Zoli
Aldo Tomasi
Maria Michela Cainazzo
Simona Guerzoni
Luigi Alberto Pini
Publication date
01-12-2015
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue Special Issue 1/2015
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1186/1129-2377-16-S1-A8

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