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The Journal of Headache and Pain
Published in: The Journal of Headache and Pain 1/2015

Open Access 01-12-2015 | Oral presentation

O044. Frequency-dependent habituation deficit of the nociceptive blink reflex in migraine with and without aura

Authors: Maria Grazia Anastasio, Armando Perrotta, Gianluca Coppola, Anna Ambrosini, Giorgio Sandrini, Roberto De Icco, Francesco Pierelli

Published in: The Journal of Headache and Pain | Special Issue 1/2015

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Excerpt

The habituation phenomenon is a frequency-dependent form of non-associative learning which reflects the excitability level of both sensory and pain systems. We previously demonstrated a frequency-dependent deficit of habituation of the conventional blink reflex in migraine[1]. We investigated the habituation of the trigeminal nociceptive system by studying the habituation of the late component (R2) of the nociceptive blink reflex (nBR) in a wide range of stimulation frequencies in subjects with migraine without aura (MWoA) and with aura (MWA). …
Literature
1.
Perrotta A, Serrao M, Sandrini G, Bogdanova D, Tassorelli C, Bartolo M, Coppola G, Pierelli F, Nappi G: Reduced habituation of trigeminal reflexes in patients with episodic cluster headache during cluster period. Cephalalgia. 2008, 28 (9): 950-9. 10.1111/j.1468-2982.2008.01631.x.CrossRefPubMed
Metadata
Title
O044. Frequency-dependent habituation deficit of the nociceptive blink reflex in migraine with and without aura
Authors
Maria Grazia Anastasio
Armando Perrotta
Gianluca Coppola
Anna Ambrosini
Giorgio Sandrini
Roberto De Icco
Francesco Pierelli
Publication date
01-12-2015
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue Special Issue 1/2015
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1186/1129-2377-16-S1-A59

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