Published in:
Open Access
01-12-2015 | Oral presentation
O046. Color vision and visual cortex excitability are impaired in episodic migraine. Simply coexisting or pathophysiologically related dysfunctions?
Authors:
Filippo Brighina, Viviana Firpo, Simona Maccora, Vittoria Calabró, Fabio Lombardo, Giuseppe Cosentino, Roberta Baschi, Nadia Bolognini, Giuseppe Vallar, Brigida Fierro
Published in:
The Journal of Headache and Pain
|
Special Issue 1/2015
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Excerpt
Evidence of abnormal color vision processing in migraine comes from observation of positive symptoms during visual aura, effects of strong color contrast triggering attacks and of colored-spectacles reducing migraine frequency. Although the central or peripheral basis of such color misperception remains unclear, several authors reported a selective deficit of shortwavelength cones (S-cones)[
1]. Sound-induced flash illusions (SIFI) are a simple way to describe visual distorsion induced by acoustic perception. SIFI critically depend on excitability of primary visual cortex (V1) as they are reduced by facilitatory anodal transcranial direct current stimulation (tDCS) over V1 in healthy subjects[
2]. We observed diminished SIFI in episodic migraine patients, especially in those with aura (MA) and during the attack[
3] in agreement with the hypothesis of visual cortex hyperexcitability. Aim of the present study was to explore the potential correlation between cones dysfunction (evaluated by colorimetric scales) and visual cortex hyperexcitability (tested by SIFI) in episodic migraine without aura patients (MoA). …